iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052703

Ensembl Protein ID

ENSLOCP00000013760.1

UniProt Accession

W5MZF1; W5MZF1_LEPOC

Genbank Protein ID

ENSLOCP00000013760

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01016735

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000011178.1	ENSLOCT00000013781.1	ENSLOCP00000013752.1
ENSLOCG00000011178.1	ENSLOCT00000013789.1	ENSLOCP00000013760.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-29	99.5	1548	1582
UBD/Beta-Prp	3.10e-44	151.5	1306	1545

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++la+ ++ ++l+sG++ g +kvW+++ ++
   Q: 1548 HKDWVCALAYvPGkPMLLSGCRGGMLKVWNVDNFT 1582
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdlet.gqclee 131
           +  +gh+++v +++  ++  +l tgs+Drt k w+l tg+ ++tlkgh ++v+s++++  ++ lv + + + i+vwd++   +c+++
   Q: 1306 SVAEGHSKPVLCLDATDE--LLFTGSKDRTCKMWNLVTGQEIVTLKGHPNNVVSVKYCS-SSCLVFTVSTSFIKVWDIRDsAKCVRT 1389
           55689*********9999..9*************************************9.88888888999*******961577777 PP
   S: 132  .....................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng...ke 194
                                t ++ +  +n ++++p+g++l ++ + +tvr Wdl++++ + +ltg h +sv +l++ +++    +
   Q: 1390 ltssgqvisgdacaatttrtiTTAQGEYQINQIALNPSGSVLYAA-AGNTVRTWDLNRMQAIGKLTG-HIGSVMCLTVGQSSgcrDQ 1474
           ********************98888888999999***88544443.4579****************9.*********988888989* PP
   S: 195  lvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlq 261
           +++gs+d +vk++d+ +g++ +   +h+      d + +++    +++l sgs D+ i+ Wdl++++l++++ 
   Q: 1475 VITGSKDHYVKVFDVAEGTVGNVGPAHNfepphyDGIECLAIN--GDILFSGSRDNGIKKWDLEQQELIQQIP 1545
           ********************88888888888888999999999..**********************999876 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MATQNDCCVK VSLRIRPQMA KEKIEGCHVC TLVTPGEPQV LLGKDKAFTY DFVFDMDAQQ 60
HQIYSNCVHK LIEGCFDGYN ATVFAYGQTG SGKTYTMGTG FDLSVSEEEQ GIIPRAVRHF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGACCCCG ACTCTTCTCC TCTCAGCACC TTCATGAACG GTGGGACCGT CAAAGGCCAC 60
GATTGGTTTG GGGTTTTGTC AAGGGGCGGG ATCCTCAGGT TTGTATGGCT AAAGTGGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	78.25	0.00e+00	2329.00
IUUC-Apl-003204	Anas platyrhynchos	78.46	0.00e+00	788.00
IUUC-Aca-004506	Anolis carolinensis	78.77	0.00e+00	1514.00
IUUC-Ame-011515	Astyanax mexicanus	83.69	0.00e+00	2586.00
IUUC-Bta-013185	Bos taurus	64.58	0.00e+00	1829.00
IUUC-Cel-018402	Caenorhabditis elegans	51.62	3.00e-149	523.00
IUUC-Cja-018844	Callithrix jacchus	76.51	0.00e+00	2320.00
IUUC-Cfa-021187	Canis familiaris	79.37	0.00e+00	2398.00
IUUC-Cpo-022444	Cavia porcellus	77.49	0.00e+00	2333.00
IUUC-Csa-023852	Chlorocebus sabaeus	79.06	0.00e+00	2406.00
IUUC-Csv-026158	Ciona savignyi	58.89	5.00e-178	619.00
IUUC-Dre-027839	Danio rerio	82.65	0.00e+00	2536.00
IUUC-Dno-030058	Dasypus novemcinctus	77.72	0.00e+00	2296.00
IUUC-Dor-030673	Dipodomys ordii	76.19	0.00e+00	2239.00
IUUC-Ete-032705	Echinops telfairi	70.90	0.00e+00	769.00
IUUC-Eca-033885	Equus caballus	78.65	0.00e+00	2336.00
IUUC-Eeu-035338	Erinaceus europaeus	66.67	0.00e+00	1798.00
IUUC-Fca-035388	Felis catus	79.12	0.00e+00	2226.00
IUUC-Fal-037044	Ficedula albicollis	79.91	0.00e+00	2476.00
IUUC-Gmo-039034	Gadus morhua	74.54	0.00e+00	1376.00
IUUC-Gac-041328	Gasterosteus aculeatus	79.85	0.00e+00	2519.00
IUUC-Ggo-045392	Gorilla gorilla	78.56	0.00e+00	2385.00
IUUC-Hsa-046713	Homo sapiens	79.00	0.00e+00	2404.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	81.44	0.00e+00	1402.00
IUUC-Lch-049786	Latimeria chalumnae	79.54	0.00e+00	2476.00
IUUC-Laf-054193	Loxodonta africana	70.89	0.00e+00	2119.00
IUUC-Mcc-055484	Macaca mulatta	77.79	0.00e+00	2363.00
IUUC-Meu-056278	Macropus eugenii	75.20	0.00e+00	1057.00
IUUC-Mga-059816	Meleagris gallopavo	77.13	0.00e+00	2363.00
IUUC-Mmr-061071	Microcebus murinus	76.73	0.00e+00	2313.00
IUUC-Mdo-062845	Monodelphis domestica	79.22	0.00e+00	2457.00
IUUC-Mmu-063967	Mus musculus	78.93	0.00e+00	2374.00
IUUC-Mpu-066448	Mustela putorius furo	78.21	0.00e+00	2384.00
IUUC-Nle-070037	Nomascus leucogenys	77.51	0.00e+00	1854.00
IUUC-Opr-070325	Ochotona princeps	75.08	0.00e+00	2227.00
IUUC-Ont-071851	Oreochromis niloticus	81.68	0.00e+00	2578.00
IUUC-Oan-073615	Ornithorhynchus anatinus	78.23	0.00e+00	2220.00
IUUC-Ocu-073855	Oryctolagus cuniculus	78.78	0.00e+00	2380.00
IUUC-Ola-086703	Oryzias latipes	79.81	0.00e+00	2479.00
IUUC-Oga-088171	Otolemur garnettii	77.43	0.00e+00	2289.00
IUUC-Oar-089693	Ovis aries	67.83	0.00e+00	1044.00
IUUC-Ptr-090535	Pan troglodytes	79.96	0.00e+00	1506.00
IUUC-Pan-091917	Papio anubis	78.24	0.00e+00	2184.00
IUUC-Psi-093752	Pelodiscus sinensis	74.16	0.00e+00	1297.00
IUUC-Pfo-096827	Poecilia formosa	76.37	0.00e+00	2367.00
IUUC-Pab-098441	Pongo abelii	79.12	0.00e+00	2405.00
IUUC-Pca-100781	Procavia capensis	82.12	0.00e+00	788.00
IUUC-Rno-105872	Rattus norvegicus	79.15	0.00e+00	2410.00
IUUC-Sha-107097	Sarcophilus harrisii	78.82	0.00e+00	2295.00
IUUC-Ssc-115638	Sus scrofa	77.29	0.00e+00	2044.00
IUUC-Tgu-116504	Taeniopygia guttata	75.68	0.00e+00	1522.00
IUUC-Tru-118242	Takifugu rubripes	79.40	0.00e+00	2523.00
IUUC-Tni-119976	Tetraodon nigroviridis	82.90	0.00e+00	987.00
IUUC-Ttr-128824	Tursiops truncatus	75.86	0.00e+00	1883.00
IUUC-Xtr-131798	Xenopus tropicalis	62.72	0.00e+00	1813.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence