iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107814

Ensembl Protein ID

EEB07284

UniProt Accession

B6K2A3; B6K2A3_SCHJY

Genbank Protein ID

EEB07284.1

Protein Name

HECT domain-containing protein

Genbank Nucleotide ID

KE651166

Gene Name

SJAG_02371

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_02371	EEB07284	EEB07284

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.30e-121	401.8	2895	3226

Active Site

Position(s)	Description	Evidence
3194	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lk.krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllg 102
           +k ++l+++f++Eeg+d+gGvtre+l+ l+++++npd+ lfl   +d++t++pn+ds + np+hl++F+f Gr++gkal+dgrlld+++s+++yk++l+
   Q: 2895 VKySKLNIRFRDEEGVDAGGVTREWLQVLARQMFNPDYALFLPVVGDSTTFHPNRDSAV-NPDHLSFFKFTGRIIGKALYDGRLLDCHFSRAVYKQILK 2992
           5525899**************************************************98.89************************************* PP
   S: 103  kklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnevi 201
            +lsl+d+e++dp++yksl ++++n   +i+++ ++ +f v+++++ge++ ++L+++G+nipVt+eNk++Yv+l+v+y+lke++k q++++ +Gf+++i
   Q: 2993 CPLSLKDMESLDPDYYKSLVWMLSN---NISDI-ITEEFAVEKDVFGERTIVDLIENGRNIPVTEENKHQYVNLMVNYKLKESVKDQLQSLCDGFYDII 3087
           ***********************99...89998.9999************************************************************* PP
   S: 202  plellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirk.dasd 295
            ++l+++F+e+elelli+G +eid++d++++t+y++ yt +sp+iqwFw+++++f++eer+++LqF+Tg+s++Pl+Gf+el+     ++f i+k ++s 
   Q: 3088 APQLVQIFNERELELLISGLPEIDIDDWRNNTEYHN-YTMSSPQIQWFWRAVRSFDEEERAKLLQFTTGTSKVPLNGFKELEgmsgFQRFNIHKsYGSL 3185
           **********************************66.***********************************************99889*****88888 PP
   S: 296  drlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           +rlP+s+TCfn+L+LPeY+s+e+l+++Ll+Ai+e+ +gF++
   Q: 3186 QRLPQSHTCFNQLDLPEYESYEQLRSMLLTAINEGsEGFGF 3226
           ***************************************86 PP

Organism

Schizosaccharomyces japonicus

Protein Sequence
(Fasta)

MKITKTPPKN QYSQPPPRIQ ELIKFVSDEK SCDEEHLIDS LTRFREESWP YPRGDLYSWI 60
PVLNRFDKVL ECLTNEYKLE EVQATPFSPA AAELLLSILR FSSFLLSHCA NRALYSSSTH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCACCTGT CCTCCTTCCC CCCAATGTTG GTGGTTTTAG TGGCAGTGGG CTATGGCCGA 60
GGGCTAGGCT GACCCTCTAC CAGTTGTCCA CCAACTTTTC ATTTCACAAA TTCTTCACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006406--P:mRNA export from nucleus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	33.52	8.00e-106	378.00
IUUC-Aml-001684	Ailuropoda melanoleuca	45.77	1.00e-127	451.00
IUUC-Atr-003044	Amborella trichopoda	40.67	2.00e-131	463.00
IUUC-Aca-005263	Anolis carolinensis	45.73	4.00e-129	456.00
IUUC-Aly-006157	Arabidopsis lyrata	40.33	6.00e-133	468.00
IUUC-Ath-007160	Arabidopsis thaliana	34.96	1.00e-130	460.00
IUUC-Ago-008005	Ashbya gossypii	39.88	0.00e+00	747.00
IUUC-Acl-008254	Aspergillus clavatus	45.19	0.00e+00	895.00
IUUC-Afl-008712	Aspergillus flavus	46.71	0.00e+00	890.00
IUUC-Afu-009022	Aspergillus fumigatus	49.11	0.00e+00	868.00
IUUC-Ani-009412	Aspergillus nidulans	47.35	0.00e+00	880.00
IUUC-Ang-009771	Aspergillus niger	48.88	0.00e+00	866.00
IUUC-Aor-010186	Aspergillus oryzae	55.59	0.00e+00	757.00
IUUC-Ate-010253	Aspergillus terreus	45.38	0.00e+00	921.00
IUUC-Ame-011067	Astyanax mexicanus	50.92	1.00e-125	444.00
IUUC-Bgr-012043	Blumeria graminis	47.49	0.00e+00	834.00
IUUC-Bta-012813	Bos taurus	45.77	9.00e-128	451.00
IUUC-Bci-013995	Botrytis cinerea	55.69	0.00e+00	764.00
IUUC-Bdi-014884	Brachypodium distachyon	36.53	1.00e-128	454.00
IUUC-Bol-016533	Brassica oleracea	54.91	1.00e-92	330.00
IUUC-Bra-016637	Brassica rapa	32.54	5.00e-129	455.00
IUUC-Cel-018179	Caenorhabditis elegans	46.58	8.00e-121	428.00
IUUC-Cja-018741	Callithrix jacchus	46.37	1.00e-127	451.00
IUUC-Cfa-020083	Canis familiaris	45.77	2.00e-127	450.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	49.88	3.00e-132	462.00
IUUC-Csa-023853	Chlorocebus sabaeus	45.77	1.00e-127	451.00
IUUC-Cho-024718	Choloepus hoffmanni	53.46	8.00e-118	417.00
IUUC-Cin-025627	Ciona intestinalis	50.83	8.00e-126	445.00
IUUC-Csv-025872	Ciona savignyi	50.47	3.00e-124	436.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	44.09	0.00e+00	818.00
IUUC-Cne-027095	Cryptococcus neoformans	36.67	6.00e-175	607.00
IUUC-Cme-027267	Cyanidioschyzon merolae	50.24	4.00e-118	418.00
IUUC-Dre-028525	Danio rerio	43.42	1.00e-110	394.00
IUUC-Dno-029680	Dasypus novemcinctus	45.77	1.00e-127	451.00
IUUC-Dor-030902	Dipodomys ordii	46.53	4.00e-108	386.00
IUUC-Dse-031197	Dothistroma septosporum	45.01	0.00e+00	791.00
IUUC-Dme-032122	Drosophila melanogaster	51.42	4.00e-125	442.00
IUUC-Ete-032966	Echinops telfairi	40.05	6.00e-92	330.00
IUUC-Eca-033915	Equus caballus	45.09	7.00e-126	445.00
IUUC-Eeu-034963	Erinaceus europaeus	50.58	2.00e-124	440.00
IUUC-Fca-035824	Felis catus	45.77	1.00e-127	451.00
IUUC-Fox-037756	Fusarium oxysporum	42.83	0.00e+00	847.00
IUUC-Fso-038464	Fusarium solani	43.21	0.00e+00	827.00
IUUC-Gmo-039073	Gadus morhua	45.77	1.00e-127	450.00
IUUC-Ggr-039946	Gaeumannomyces graminis	47.47	0.00e+00	830.00
IUUC-Gga-040309	Gallus gallus	55.70	3.00e-101	359.00
IUUC-Gac-042430	Gasterosteus aculeatus	45.77	1.00e-127	450.00
IUUC-Gma-042956	Glycine max	45.68	1.00e-130	461.00
IUUC-Hsa-046879	Homo sapiens	45.77	2.00e-127	450.00
IUUC-Hvu-047697	Hordeum vulgare	33.94	4.00e-131	462.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	45.77	4.00e-128	451.00
IUUC-Kpa-049228	Komagataella pastoris	46.77	0.00e+00	813.00
IUUC-Lch-050252	Latimeria chalumnae	45.87	4.00e-127	449.00
IUUC-Lpe-051550	Leersia perrieri	45.64	1.00e-131	464.00
IUUC-Loc-052472	Lepisosteus oculatus	45.96	3.00e-128	452.00
IUUC-Lma-053159	Leptosphaeria maculans	47.86	0.00e+00	849.00
IUUC-Laf-054154	Loxodonta africana	45.77	9.00e-128	451.00
IUUC-Mcc-055085	Macaca mulatta	45.77	9.00e-128	451.00
IUUC-Mor-057201	Magnaporthe oryzae	48.14	0.00e+00	838.00
IUUC-Mpo-057597	Magnaporthe poae	57.46	0.00e+00	756.00
IUUC-Mtr-057633	Medicago truncatula	39.01	2.00e-132	466.00
IUUC-Mla-058888	Melampsora laricipopulina	57.04	2.00e-144	503.00
IUUC-Mvi-060320	Microbotryum violaceum	41.62	0.00e+00	679.00
IUUC-Mmr-060820	Microcebus murinus	45.77	1.00e-127	450.00
IUUC-Mdo-062930	Monodelphis domestica	45.73	6.00e-129	455.00
IUUC-Mmu-063601	Mus musculus	45.77	1.00e-127	450.00
IUUC-Mac-065557	Musa acuminata	40.99	2.00e-121	430.00
IUUC-Mpu-066653	Mustela putorius furo	45.77	1.00e-127	451.00
IUUC-Mlu-067418	Myotis lucifugus	45.54	2.00e-128	453.00
IUUC-Nfi-068278	Neosartorya fischeri	45.81	0.00e+00	919.00
IUUC-Ncr-068813	Neurospora crassa	57.32	0.00e+00	782.00
IUUC-Nle-069418	Nomascus leucogenys	45.77	2.00e-127	450.00
IUUC-Ont-071300	Oreochromis niloticus	45.77	1.00e-127	451.00
IUUC-Oan-073046	Ornithorhynchus anatinus	45.75	3.00e-128	453.00
IUUC-Ocu-074178	Oryctolagus cuniculus	45.77	7.00e-128	451.00
IUUC-Oba-075757	Oryza barthii	38.61	4.00e-133	469.00
IUUC-Obr-076553	Oryza brachyantha	38.76	4.00e-133	469.00
IUUC-Ogl-077520	Oryza glaberrima	38.61	5.00e-133	468.00
IUUC-Ogu-078278	Oryza glumaepatula	38.76	2.00e-133	469.00
IUUC-Oin-079767	Oryza indica	38.76	2.00e-133	469.00
IUUC-Olo-080380	Oryza longistaminata	38.53	1.00e-131	464.00
IUUC-Ome-081925	Oryza meridionalis	38.38	3.00e-131	462.00
IUUC-Oni-082619	Oryza nivara	38.76	3.00e-133	469.00
IUUC-Opu-083684	Oryza punctata	37.23	4.00e-132	465.00
IUUC-Oru-084501	Oryza rufipogon	38.76	2.00e-133	469.00
IUUC-Osa-086251	Oryza sativa	38.76	1.00e-133	468.00
IUUC-Olu-087813	Ostreococcus lucimarinus	46.93	2.00e-113	400.00
IUUC-Oga-088903	Otolemur garnettii	45.77	2.00e-127	450.00
IUUC-Oar-090210	Ovis aries	45.77	2.00e-127	450.00
IUUC-Pan-092368	Papio anubis	43.62	3.00e-111	396.00
IUUC-Pno-094871	Phaeosphaeria nodorum	47.26	0.00e+00	840.00
IUUC-Ppa-095657	Physcomitrella patens	49.19	2.00e-128	453.00
IUUC-Pfo-096232	Poecilia formosa	45.77	1.00e-127	451.00
IUUC-Pab-098583	Pongo abelii	45.77	1.00e-127	451.00
IUUC-Pop-099468	Populus trichocarpa	38.77	1.00e-134	474.00
IUUC-Ppe-101641	Prunus persica	31.46	1.00e-136	480.00
IUUC-Pva-102116	Pteropus vampyrus	43.27	2.00e-115	410.00
IUUC-Pgr-103465	Puccinia graminis	38.31	0.00e+00	649.00
IUUC-Ptt-103813	Puccinia triticina	37.81	5.00e-177	615.00
IUUC-Pte-104018	Pyrenophora teres	44.43	0.00e+00	855.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	45.07	0.00e+00	857.00
IUUC-Sce-106449	Saccharomyces cerevisiae	41.17	0.00e+00	785.00
IUUC-Sha-106961	Sarcophilus harrisii	45.73	7.00e-129	455.00
IUUC-Spo-108024	Schizosaccharomyces pombe	51.08	0.00e+00	2952.00
IUUC-Smo-109640	Selaginella moellendorffii	39.81	2.00e-132	466.00
IUUC-Sit-110598	Setaria italica	36.86	8.00e-133	468.00
IUUC-Sly-111706	Solanum lycopersicum	40.51	5.00e-132	465.00
IUUC-Sar-113291	Sorex araneus	51.45	2.00e-121	430.00
IUUC-Sbi-114042	Sorghum bicolor	31.95	4.00e-136	478.00
IUUC-Sre-114958	Sporisorium reilianum	53.73	4.00e-169	585.00
IUUC-Ssc-115754	Sus scrofa	45.77	1.00e-127	450.00
IUUC-Tru-118570	Takifugu rubripes	45.77	1.00e-127	451.00
IUUC-Tsy-119407	Tarsius syrichta	42.93	8.00e-89	319.00
IUUC-Tni-120836	Tetraodon nigroviridis	45.38	4.00e-124	438.00
IUUC-Tca-121479	Theobroma cacao	45.77	2.00e-131	463.00
IUUC-Tre-121909	Trichoderma reesei	44.49	0.00e+00	853.00
IUUC-Tvi-122370	Trichoderma virens	43.82	0.00e+00	845.00
IUUC-Tae-125214	Triticum aestivum	35.92	3.00e-125	441.00
IUUC-Tme-127172	Tuber melanosporum	45.77	0.00e+00	938.00
IUUC-Ttr-129253	Tursiops truncatus	45.77	2.00e-127	449.00
IUUC-Uma-129355	Ustilago maydis	55.05	7.00e-172	595.00
IUUC-Vda-129886	Verticillium dahliae	55.64	0.00e+00	746.00
IUUC-Vpa-130708	Vicugna pacos	45.77	3.00e-127	449.00
IUUC-Vvi-131078	Vitis vinifera	44.74	2.00e-128	453.00
IUUC-Xtr-132123	Xenopus tropicalis	43.95	9.00e-118	418.00
IUUC-Xma-133869	Xiphophorus maculatus	45.77	1.00e-127	451.00
IUUC-Yli-134657	Yarrowia lipolytica	46.86	0.00e+00	767.00
IUUC-Zma-135570	Zea mays	33.26	4.00e-134	472.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence