iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120548

Ensembl Protein ID

ENSTNIP00000011096.1

UniProt Accession

H3CS62; H3CS62_TETNG

Protein Name

Uncharacterized protein

Gene Name

VAV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000008266.1	ENSTNIT00000011278.1	ENSTNIP00000011096.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-18	66.3	794	844

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++ y+++a +  eL+l++Gd+++++  ++   gW+kg  e  g+ GlfP+n+v 
   Q: 794  RARYNFSARDRSELSLQEGDTIKIL-SKKGHTGWWKG--EVYGRVGLFPANYVD 844
           688**********************.99999******..9************97 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MELWRQCAAW LIDCRVLPDN HRVTWQSAQV CDLAQALRDG VLLCQLLNNL LPQAVNLREI 60
NLRPQMSQFL CLKNIRTFLA ACQTKFYLKK SELFEAFDLF DVRDFGKVID TLSTLSRSHI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTTGT GGCGACAGTG CGCGGCGTGG TTGATCGACT GTCGAGTCCT TCCTGATAAC 60
CACCGGGTGA CATGGCAAAG CGCACAGGTG AGCCGGCCGC TTGGTTCGGT TGCACACCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR028530--Vav

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018578	Caenorhabditis elegans	31.43	5.00e-73	269.00
IUUC-Cja-020009	Callithrix jacchus	64.72	0.00e+00	1093.00
IUUC-Cfa-020768	Canis familiaris	65.11	0.00e+00	1076.00
IUUC-Csv-025995	Ciona savignyi	35.68	3.00e-135	475.00
IUUC-Dno-029602	Dasypus novemcinctus	65.11	0.00e+00	1077.00
IUUC-Eca-033682	Equus caballus	64.87	0.00e+00	1071.00
IUUC-Fca-035629	Felis catus	65.11	0.00e+00	1126.00
IUUC-Gmo-039693	Gadus morhua	68.27	0.00e+00	1114.00
IUUC-Gac-041567	Gasterosteus aculeatus	76.87	0.00e+00	1222.00
IUUC-Hsa-045886	Homo sapiens	64.84	0.00e+00	1094.00
IUUC-Itr-048730	Ictidomys tridecemlineatus	62.53	0.00e+00	1019.00
IUUC-Loc-051761	Lepisosteus oculatus	70.84	0.00e+00	1191.00
IUUC-Laf-054537	Loxodonta africana	65.19	0.00e+00	1088.00
IUUC-Mcc-054726	Macaca mulatta	64.95	0.00e+00	1096.00
IUUC-Mmr-060980	Microcebus murinus	63.49	0.00e+00	1060.00
IUUC-Mdo-061926	Monodelphis domestica	62.48	0.00e+00	946.00
IUUC-Mmu-063942	Mus musculus	64.99	0.00e+00	1084.00
IUUC-Mpu-066000	Mustela putorius furo	64.99	0.00e+00	1074.00
IUUC-Mlu-067818	Myotis lucifugus	63.80	0.00e+00	1062.00
IUUC-Ont-072213	Oreochromis niloticus	79.93	0.00e+00	1325.00
IUUC-Ola-087345	Oryzias latipes	74.00	0.00e+00	1226.00
IUUC-Oga-089104	Otolemur garnettii	64.64	0.00e+00	1076.00
IUUC-Oar-089459	Ovis aries	64.83	0.00e+00	1092.00
IUUC-Ptr-090766	Pan troglodytes	63.20	0.00e+00	994.00
IUUC-Pan-091994	Papio anubis	64.29	0.00e+00	1077.00
IUUC-Psi-093595	Pelodiscus sinensis	63.50	0.00e+00	1030.00
IUUC-Pfo-097210	Poecilia formosa	78.85	0.00e+00	1284.00
IUUC-Pab-098630	Pongo abelii	64.52	0.00e+00	1061.00
IUUC-Pva-102406	Pteropus vampyrus	63.93	0.00e+00	1014.00
IUUC-Rno-105763	Rattus norvegicus	62.76	0.00e+00	1030.00
IUUC-Sha-106683	Sarcophilus harrisii	65.22	0.00e+00	1139.00
IUUC-Ssc-115338	Sus scrofa	63.53	0.00e+00	1005.00
IUUC-Tru-118199	Takifugu rubripes	86.70	0.00e+00	1379.00
IUUC-Vpa-130066	Vicugna pacos	53.42	2.00e-38	154.00
IUUC-Xtr-132410	Xenopus tropicalis	64.02	0.00e+00	1073.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence