iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134337

Ensembl Protein ID

CAG78780

UniProt Accession

Q6C044; ATG18_YARLI

Genbank Protein ID

CAG78780.1

Protein Name

Autophagy-related protein 18

Genbank Nucleotide ID

CR382132

Gene Name

ATG18; YALI0F27907g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_F27907g	CAG78780	CAG78780

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-06	24.7	194	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgt.ikvWDlr 31
           H+ +  cl++ sd tll+++sd gt i+v+++ 
   Q: 194  HKTPLACLSLnSDgTLLATASDKGTiIRVFSVP 226
           77778899999999***********99999976 PP

Organism

Yarrowia lipolytica

Functional Description
(View)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

Protein Sequence
(Fasta)

MSDSINFVSF NQDYSCVSVG TPQGYKIYNC DPFGKCFSKA DGGMGIVEML FCTSLIAVVG 60
MGDQPQNSPR RLKIVNTKRQ STICELTFPT AVLGVRLNRQ RLVVLLQDQI YIYDISNMKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGACT CGATCAACTT TGTGTCCTTC AACCAGGACT ACAGTTGTGT GTCTGTCGGC 60
ACCCCTCAGG GCTACAAAAT CTACAACTGC GACCCGTTCG GCAAATGCTT CTCCAAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0010008--C:endosome membrane
GO:0034045--C:pre-autophagosomal structure membrane
GO:0005774--C:vacuolar membrane
GO:0006914--P:autophagy
GO:0015031--P:protein transport

KEGG

yli:YALI0F27907g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000966	Aegilops tauschii	33.60	4.00e-52	196.00
IUUC-Aml-001842	Ailuropoda melanoleuca	38.05	3.00e-63	233.00
IUUC-Atr-002710	Amborella trichopoda	35.62	2.00e-51	194.00
IUUC-Apl-003390	Anas platyrhynchos	37.28	6.00e-62	229.00
IUUC-Aca-004975	Anolis carolinensis	37.59	2.00e-64	237.00
IUUC-Aly-006332	Arabidopsis lyrata	32.12	1.00e-51	194.00
IUUC-Ath-007660	Arabidopsis thaliana	32.64	1.00e-46	178.00
IUUC-Ago-007948	Ashbya gossypii	33.65	2.00e-64	238.00
IUUC-Acl-008148	Aspergillus clavatus	47.48	4.00e-103	365.00
IUUC-Afl-008562	Aspergillus flavus	48.25	1.00e-103	367.00
IUUC-Afu-008936	Aspergillus fumigatus	48.64	2.00e-103	367.00
IUUC-Ani-009254	Aspergillus nidulans	49.54	2.00e-106	377.00
IUUC-Ang-009798	Aspergillus niger	48.62	3.00e-104	369.00
IUUC-Aor-010066	Aspergillus oryzae	48.25	1.00e-103	367.00
IUUC-Ate-010266	Aspergillus terreus	48.62	1.00e-105	374.00
IUUC-Ame-010727	Astyanax mexicanus	37.59	2.00e-64	237.00
IUUC-Bta-012655	Bos taurus	37.59	7.00e-65	239.00
IUUC-Bci-013627	Botrytis cinerea	48.72	5.00e-101	359.00
IUUC-Bdi-014739	Brachypodium distachyon	33.77	3.00e-53	200.00
IUUC-Bol-015492	Brassica oleracea	33.78	3.00e-51	193.00
IUUC-Cel-018503	Caenorhabditis elegans	32.92	5.00e-51	192.00
IUUC-Cja-018829	Callithrix jacchus	35.01	3.00e-56	210.00
IUUC-Cfa-020858	Canis familiaris	37.79	4.00e-63	233.00
IUUC-Cpo-022235	Cavia porcellus	36.84	3.00e-62	230.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	38.89	5.00e-50	189.00
IUUC-Csa-023963	Chlorocebus sabaeus	35.01	7.00e-58	216.00
IUUC-Cho-024328	Choloepus hoffmanni	39.48	6.00e-60	223.00
IUUC-Cin-025343	Ciona intestinalis	36.32	7.00e-57	212.00
IUUC-Csv-025920	Ciona savignyi	37.78	1.00e-62	231.00
IUUC-Cgl-026425	Colletotrichum gloeosporioides	55.06	5.00e-39	152.00
IUUC-Cne-026947	Cryptococcus neoformans	53.63	3.00e-112	396.00
IUUC-Dre-027490	Danio rerio	37.84	7.00e-65	239.00
IUUC-Dno-030057	Dasypus novemcinctus	38.05	1.00e-62	231.00
IUUC-Dor-030472	Dipodomys ordii	37.57	4.00e-57	213.00
IUUC-Dse-031215	Dothistroma septosporum	37.47	1.00e-83	301.00
IUUC-Ete-032362	Echinops telfairi	39.33	3.00e-55	206.00
IUUC-Eca-034362	Equus caballus	37.79	2.00e-62	231.00
IUUC-Eeu-034479	Erinaceus europaeus	35.47	5.00e-21	92.40
IUUC-Fca-036230	Felis catus	37.89	2.00e-62	230.00
IUUC-Fal-036782	Ficedula albicollis	36.99	2.00e-61	227.00
IUUC-Fox-037797	Fusarium oxysporum	47.22	9.00e-100	355.00
IUUC-Fso-038174	Fusarium solani	55.22	2.00e-77	280.00
IUUC-Gmo-039706	Gadus morhua	35.23	3.00e-55	207.00
IUUC-Ggr-040113	Gaeumannomyces graminis	57.25	6.00e-83	299.00
IUUC-Gga-040690	Gallus gallus	37.38	2.00e-65	240.00
IUUC-Gac-041360	Gasterosteus aculeatus	37.82	4.00e-65	239.00
IUUC-Gma-043876	Glycine max	34.91	3.00e-58	216.00
IUUC-Hsa-046782	Homo sapiens	36.25	1.00e-58	218.00
IUUC-Hvu-047851	Hordeum vulgare	33.60	6.00e-52	196.00
IUUC-Itr-048693	Ictidomys tridecemlineatus	35.49	2.00e-59	221.00
IUUC-Kpa-049378	Komagataella pastoris	54.93	5.00e-88	316.00
IUUC-Lch-050413	Latimeria chalumnae	38.59	6.00e-60	222.00
IUUC-Lpe-051205	Leersia perrieri	33.07	7.00e-52	195.00
IUUC-Lma-052948	Leptosphaeria maculans	50.12	1.00e-111	394.00
IUUC-Laf-054007	Loxodonta africana	37.62	3.00e-65	240.00
IUUC-Mor-057125	Magnaporthe oryzae	56.13	2.00e-82	297.00
IUUC-Mtr-058609	Medicago truncatula	32.11	3.00e-39	154.00
IUUC-Mga-059795	Meleagris gallopavo	37.28	4.00e-62	229.00
IUUC-Mvi-060219	Microbotryum violaceum	50.71	8.00e-110	388.00
IUUC-Mmr-061096	Microcebus murinus	36.21	6.00e-62	229.00
IUUC-Mdo-062881	Monodelphis domestica	37.38	8.00e-66	241.00
IUUC-Mmu-063787	Mus musculus	38.10	5.00e-67	246.00
IUUC-Mac-064838	Musa acuminata	34.02	4.00e-54	203.00
IUUC-Mpu-066019	Mustela putorius furo	34.76	2.00e-59	220.00
IUUC-Mlu-068016	Myotis lucifugus	37.62	4.00e-66	243.00
IUUC-Nfi-068424	Neosartorya fischeri	48.96	9.00e-105	371.00
IUUC-Ncr-068833	Neurospora crassa	47.21	1.00e-101	361.00
IUUC-Opr-070933	Ochotona princeps	37.79	3.00e-44	170.00
IUUC-Ont-072495	Oreochromis niloticus	38.10	6.00e-66	242.00
IUUC-Oan-073084	Ornithorhynchus anatinus	38.70	3.00e-60	223.00
IUUC-Ocu-074689	Oryctolagus cuniculus	37.34	4.00e-63	233.00
IUUC-Oba-075827	Oryza barthii	33.94	1.00e-52	198.00
IUUC-Obr-076476	Oryza brachyantha	33.68	2.00e-52	197.00
IUUC-Ogl-077630	Oryza glaberrima	33.94	1.00e-52	198.00
IUUC-Ogu-078126	Oryza glumaepatula	33.42	1.00e-52	198.00
IUUC-Oin-080115	Oryza indica	33.94	1.00e-52	198.00
IUUC-Olo-080657	Oryza longistaminata	33.94	2.00e-51	196.00
IUUC-Ome-081702	Oryza meridionalis	33.42	1.00e-49	188.00
IUUC-Oni-082884	Oryza nivara	33.94	3.00e-52	197.00
IUUC-Opu-083460	Oryza punctata	33.94	5.00e-52	197.00
IUUC-Oru-084193	Oryza rufipogon	33.94	1.00e-52	198.00
IUUC-Osa-085948	Oryza sativa	33.94	1.00e-52	198.00
IUUC-Olu-087808	Ostreococcus lucimarinus	32.90	3.00e-54	203.00
IUUC-Oga-088894	Otolemur garnettii	35.25	6.00e-59	219.00
IUUC-Oar-089850	Ovis aries	37.02	2.00e-61	227.00
IUUC-Ptr-090456	Pan troglodytes	36.25	1.00e-58	218.00
IUUC-Pan-092111	Papio anubis	36.59	6.00e-62	229.00
IUUC-Psi-094095	Pelodiscus sinensis	36.99	5.00e-62	229.00
IUUC-Pno-095015	Phaeosphaeria nodorum	47.88	1.00e-100	357.00
IUUC-Ppa-095480	Physcomitrella patens	36.62	1.00e-49	188.00
IUUC-Pfo-096987	Poecilia formosa	37.84	6.00e-66	242.00
IUUC-Pab-097754	Pongo abelii	36.25	2.00e-58	218.00
IUUC-Pop-099157	Populus trichocarpa	32.07	3.00e-50	190.00
IUUC-Ppe-101799	Prunus persica	34.54	7.00e-45	172.00
IUUC-Pva-103047	Pteropus vampyrus	37.70	2.00e-61	227.00
IUUC-Pte-104139	Pyrenophora teres	48.35	3.00e-101	359.00
IUUC-Pyt-104488	Pyrenophora triticirepentis	48.82	2.00e-101	360.00
IUUC-Rno-105990	Rattus norvegicus	38.10	5.00e-67	246.00
IUUC-Sce-106327	Saccharomyces cerevisiae	37.80	5.00e-93	332.00
IUUC-Sha-106581	Sarcophilus harrisii	37.28	2.00e-61	228.00
IUUC-Sja-107913	Schizosaccharomyces japonicus	45.27	4.00e-88	316.00
IUUC-Spo-108068	Schizosaccharomyces pombe	45.60	2.00e-81	293.00
IUUC-Ssl-108418	Sclerotinia sclerotiorum	49.53	3.00e-112	396.00
IUUC-Smo-109446	Selaginella moellendorffii	37.14	1.00e-57	214.00
IUUC-Sly-111030	Solanum lycopersicum	33.25	3.00e-49	187.00
IUUC-Stu-112534	Solanum tuberosum	31.27	2.00e-47	181.00
IUUC-Sar-113276	Sorex araneus	35.47	4.00e-21	92.40
IUUC-Sbi-114020	Sorghum bicolor	32.45	6.00e-49	186.00
IUUC-Sre-115219	Sporisorium reilianum	51.14	8.00e-112	395.00
IUUC-Ssc-116360	Sus scrofa	38.10	1.00e-65	241.00
IUUC-Tgu-116951	Taeniopygia guttata	37.28	5.00e-62	229.00
IUUC-Tru-117889	Takifugu rubripes	36.54	2.00e-62	230.00
IUUC-Tre-121895	Trichoderma reesei	47.77	5.00e-108	382.00
IUUC-Tvi-122311	Trichoderma virens	46.46	3.00e-108	383.00
IUUC-Tae-124901	Triticum aestivum	33.60	3.00e-52	196.00
IUUC-Tur-126757	Triticum urartu	33.33	4.00e-51	193.00
IUUC-Uma-129438	Ustilago maydis	51.52	4.00e-103	366.00
IUUC-Vda-129782	Verticillium dahliae	55.98	8.00e-51	192.00
IUUC-Vvi-131674	Vitis vinifera	34.63	6.00e-53	199.00
IUUC-Xma-133370	Xiphophorus maculatus	37.84	6.00e-66	242.00
IUUC-Zma-135902	Zea mays	31.52	5.00e-44	169.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence