iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044518

UUCD1 version

UUC-GoG-00470

Ensembl Protein ID

ENSGGOP00000011502.2

UniProt Accession

G3R802; G3R802_GORGO

Protein Name

Uncharacterized protein

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000011793.2	ENSGGOT00000011835.2	ENSGGOP00000011502.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.20e-08	35.7	13	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle+fk+ p+++pCgH f+ +Cl + w     ++    +CP Cr
   Q: 13   CSICLEPFKE-PVTTPCGHNFCGSCLnETW----AVQGAPYLCPQCR 54
           ********99.****************9**....8999999*****8 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

TAPLLPXAEE LSCSICLEPF KEPVTTPCGH NFCGSCLNET WAVQGAPYLC PQCRAVYQAR 60
PQLHKNTVLC NVVEQFLQAD LAREPPADGW TPPARASAPS PDAQVACDHC LKEAAVKTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGCTCCAC TCCTCCCTTT GGAGGCAGCA TTTTATGGTA GGAAACTCCT GGCTTTGGAA 60
AGCAGATGGG CTGTGTGCCA ATGTCCATTC TTAGACACGT TATTTAGTTT CTCTAAGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	76.46	0.00e+00	950.00
IUUC-Apl-004101	Anas platyrhynchos	49.11	1.00e-164	572.00
IUUC-Aca-005025	Anolis carolinensis	48.75	5.00e-172	597.00
IUUC-Bta-012735	Bos taurus	74.29	0.00e+00	930.00
IUUC-Cja-019996	Callithrix jacchus	81.96	0.00e+00	709.00
IUUC-Cfa-020466	Canis familiaris	74.49	0.00e+00	949.00
IUUC-Cpo-021737	Cavia porcellus	70.19	0.00e+00	862.00
IUUC-Csa-023217	Chlorocebus sabaeus	93.50	0.00e+00	1131.00
IUUC-Cho-024346	Choloepus hoffmanni	50.50	7.00e-70	257.00
IUUC-Dre-027570	Danio rerio	34.07	4.00e-42	165.00
IUUC-Dno-030082	Dasypus novemcinctus	75.12	0.00e+00	930.00
IUUC-Dor-030335	Dipodomys ordii	52.53	2.00e-124	439.00
IUUC-Ete-032923	Echinops telfairi	69.34	0.00e+00	776.00
IUUC-Eca-033411	Equus caballus	74.92	0.00e+00	929.00
IUUC-Eeu-034656	Erinaceus europaeus	72.51	3.00e-159	555.00
IUUC-Fca-035371	Felis catus	77.17	0.00e+00	956.00
IUUC-Fal-037008	Ficedula albicollis	45.21	6.00e-156	544.00
IUUC-Gmo-038668	Gadus morhua	33.71	4.00e-101	362.00
IUUC-Gga-040608	Gallus gallus	47.28	7.00e-160	557.00
IUUC-Gac-041409	Gasterosteus aculeatus	51.65	3.00e-57	216.00
IUUC-Hsa-045828	Homo sapiens	97.78	0.00e+00	1164.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	56.47	0.00e+00	653.00
IUUC-Lch-050478	Latimeria chalumnae	39.07	6.00e-70	258.00
IUUC-Loc-052864	Lepisosteus oculatus	36.70	4.00e-112	398.00
IUUC-Laf-054325	Loxodonta africana	77.17	1.00e-169	588.00
IUUC-Mcc-054920	Macaca mulatta	94.14	0.00e+00	1137.00
IUUC-Meu-056367	Macropus eugenii	72.83	5.00e-74	272.00
IUUC-Mga-059975	Meleagris gallopavo	49.37	1.00e-162	566.00
IUUC-Mmr-060748	Microcebus murinus	81.46	0.00e+00	986.00
IUUC-Mdo-062904	Monodelphis domestica	57.81	0.00e+00	684.00
IUUC-Mmu-063891	Mus musculus	72.24	0.00e+00	922.00
IUUC-Mpu-066473	Mustela putorius furo	76.36	0.00e+00	972.00
IUUC-Mlu-068185	Myotis lucifugus	77.90	0.00e+00	934.00
IUUC-Nle-070177	Nomascus leucogenys	95.56	0.00e+00	1151.00
IUUC-Opr-070558	Ochotona princeps	60.57	2.00e-144	505.00
IUUC-Ont-071368	Oreochromis niloticus	47.80	1.00e-52	201.00
IUUC-Ocu-074461	Oryctolagus cuniculus	67.97	1.00e-150	526.00
IUUC-Ola-087394	Oryzias latipes	29.79	2.00e-61	230.00
IUUC-Oga-088937	Otolemur garnettii	74.29	0.00e+00	921.00
IUUC-Oar-089781	Ovis aries	74.72	7.00e-179	619.00
IUUC-Ptr-090771	Pan troglodytes	98.26	0.00e+00	1164.00
IUUC-Pan-092830	Papio anubis	93.66	0.00e+00	1132.00
IUUC-Psi-093664	Pelodiscus sinensis	51.96	2.00e-177	615.00
IUUC-Pma-094147	Petromyzon marinus	28.26	1.00e-60	228.00
IUUC-Pfo-096528	Poecilia formosa	34.97	1.00e-58	220.00
IUUC-Pab-097588	Pongo abelii	95.09	0.00e+00	1145.00
IUUC-Pca-100890	Procavia capensis	74.07	2.00e-158	552.00
IUUC-Pva-102314	Pteropus vampyrus	80.60	0.00e+00	950.00
IUUC-Pgr-103377	Puccinia graminis	40.38	4.00e-06	46.20
IUUC-Ptt-103758	Puccinia triticina	40.38	1.00e-05	43.50
IUUC-Rno-105234	Rattus norvegicus	69.24	0.00e+00	895.00
IUUC-Sce-106362	Saccharomyces cerevisiae	44.93	8.00e-09	54.70
IUUC-Sha-106807	Sarcophilus harrisii	53.50	0.00e+00	639.00
IUUC-Sar-113283	Sorex araneus	58.90	4.00e-131	461.00
IUUC-Ssc-115878	Sus scrofa	80.34	9.00e-106	375.00
IUUC-Tgu-117026	Taeniopygia guttata	45.38	1.00e-127	449.00
IUUC-Tru-118500	Takifugu rubripes	27.89	2.00e-52	199.00
IUUC-Tni-120550	Tetraodon nigroviridis	27.86	2.00e-66	246.00
IUUC-Tbe-127580	Tupaia belangeri	72.80	3.00e-155	541.00
IUUC-Ttr-128648	Tursiops truncatus	71.97	0.00e+00	636.00
IUUC-Vpa-130254	Vicugna pacos	89.71	2.00e-97	349.00
IUUC-Xtr-132892	Xenopus tropicalis	42.27	4.00e-73	268.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence