iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002222

Ensembl Protein ID

ENSAMEP00000003616.1

UniProt Accession

G1L9P3; G1L9P3_AILME

Genbank Protein ID

ENSAMEP00000003616

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01185036

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000003383.1	ENSAMET00000003761.1	ENSAMEP00000003616.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	94.04	0.00e+00	921.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

VKMVDTESPI CPLSPLEADD LESPLSEEFL QEMGSIQEIS QSIGEDSSGS FSFTEYQYLG 60
SGPGSDGSVI TDTLSPASSP SSVTYPVAPS SADEPASVAL NIECRICGDR ASGYHYGVHA 120

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Nucleotide Sequence
(Fasta)

GTCAAGATGG TAGACACAGA AAGCCCAATT TGCCCCCTCT CCCCGCTCGA GGCTGATGAT 60
CTGGAAAGCC CATTATCTGA AGAATTTCTA CAAGAAATGG GAAGCATCCA AGAGATTTCT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003330	Anas platyrhynchos	87.34	0.00e+00	839.00
IUUC-Aca-004598	Anolis carolinensis	84.75	0.00e+00	820.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.50e-01	29.30
IUUC-Ame-011508	Astyanax mexicanus	73.73	0.00e+00	697.00
IUUC-Bta-012621	Bos taurus	93.43	0.00e+00	890.00
IUUC-Cja-019688	Callithrix jacchus	93.19	0.00e+00	879.00
IUUC-Cfa-020859	Canis familiaris	96.60	0.00e+00	944.00
IUUC-Cpo-021607	Cavia porcellus	86.60	0.00e+00	824.00
IUUC-Csa-023313	Chlorocebus sabaeus	93.40	0.00e+00	877.00
IUUC-Cho-024741	Choloepus hoffmanni	82.98	0.00e+00	745.00
IUUC-Cgl-026615	Colletotrichum gloeosporioides	34.48	3.90e-01	27.30
IUUC-Dre-027446	Danio rerio	72.03	0.00e+00	682.00
IUUC-Dno-029173	Dasypus novemcinctus	91.10	0.00e+00	856.00
IUUC-Dor-030581	Dipodomys ordii	89.34	0.00e+00	806.00
IUUC-Ete-032330	Echinops telfairi	90.21	0.00e+00	876.00
IUUC-Eca-033712	Equus caballus	93.64	0.00e+00	878.00
IUUC-Fca-036555	Felis catus	97.23	0.00e+00	957.00
IUUC-Fal-036677	Ficedula albicollis	86.38	0.00e+00	825.00
IUUC-Gmo-039240	Gadus morhua	81.12	0.00e+00	636.00
IUUC-Gga-040473	Gallus gallus	87.66	0.00e+00	837.00
IUUC-Gac-041872	Gasterosteus aculeatus	72.00	0.00e+00	700.00
IUUC-Ggo-045226	Gorilla gorilla	94.04	0.00e+00	885.00
IUUC-Hsa-046893	Homo sapiens	94.04	0.00e+00	885.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	91.06	0.00e+00	864.00
IUUC-Lch-050116	Latimeria chalumnae	78.94	0.00e+00	763.00
IUUC-Loc-052131	Lepisosteus oculatus	82.59	0.00e+00	683.00
IUUC-Laf-054323	Loxodonta africana	93.40	0.00e+00	884.00
IUUC-Mcc-054841	Macaca mulatta	93.86	0.00e+00	883.00
IUUC-Meu-056833	Macropus eugenii	82.34	0.00e+00	749.00
IUUC-Mtr-058471	Medicago truncatula	29.82	1.90e-01	30.00
IUUC-Mga-059995	Meleagris gallopavo	78.81	0.00e+00	741.00
IUUC-Mdo-061954	Monodelphis domestica	89.96	0.00e+00	773.00
IUUC-Mmu-064295	Mus musculus	89.57	0.00e+00	817.00
IUUC-Mpu-066216	Mustela putorius furo	96.60	0.00e+00	946.00
IUUC-Nle-069970	Nomascus leucogenys	93.83	0.00e+00	882.00
IUUC-Ont-071594	Oreochromis niloticus	73.05	0.00e+00	691.00
IUUC-Oan-073501	Ornithorhynchus anatinus	89.29	0.00e+00	757.00
IUUC-Ocu-074634	Oryctolagus cuniculus	82.97	0.00e+00	820.00
IUUC-Oni-082926	Oryza nivara	27.45	1.20e-02	30.80
IUUC-Ola-086585	Oryzias latipes	78.89	0.00e+00	627.00
IUUC-Oga-088738	Otolemur garnettii	94.70	0.00e+00	882.00
IUUC-Oar-090453	Ovis aries	93.43	0.00e+00	889.00
IUUC-Ptr-091518	Pan troglodytes	93.83	0.00e+00	878.00
IUUC-Pan-092006	Papio anubis	93.83	0.00e+00	879.00
IUUC-Psi-093352	Pelodiscus sinensis	85.38	0.00e+00	830.00
IUUC-Pfo-096060	Poecilia formosa	72.21	0.00e+00	686.00
IUUC-Pab-098602	Pongo abelii	87.61	0.00e+00	784.00
IUUC-Pva-102175	Pteropus vampyrus	88.30	0.00e+00	855.00
IUUC-Rno-105283	Rattus norvegicus	90.00	0.00e+00	822.00
IUUC-Sce-106436	Saccharomyces cerevisiae	27.42	4.10e-02	29.60
IUUC-Sha-106560	Sarcophilus harrisii	91.08	0.00e+00	859.00
IUUC-Smo-109075	Selaginella moellendorffii	30.00	8.20e-02	30.00
IUUC-Ssc-115266	Sus scrofa	95.11	0.00e+00	933.00
IUUC-Tgu-116778	Taeniopygia guttata	86.23	0.00e+00	828.00
IUUC-Tru-118436	Takifugu rubripes	70.95	0.00e+00	683.00
IUUC-Tsy-119642	Tarsius syrichta	81.06	0.00e+00	733.00
IUUC-Tni-119859	Tetraodon nigroviridis	71.16	0.00e+00	680.00
IUUC-Tvi-122624	Trichoderma virens	30.91	2.90e-01	27.70
IUUC-Tbe-127464	Tupaia belangeri	92.77	0.00e+00	903.00
IUUC-Ttr-129307	Tursiops truncatus	90.87	0.00e+00	842.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence