iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073208

UUCD1 version

UUC-OrA-00848

Ensembl Protein ID

ENSOANP00000007497.2

UniProt Accession

F7DKL7; F7DKL7_ORNAN

Protein Name

Uncharacterized protein

Gene Name

USP47

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000004734.2	ENSOANT00000007499.2	ENSOANP00000007497.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.30e-76	256.9	176	550

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+  tCY+NS+LQ+L+++pe+r++l + + e+ +    ++p +++  +lq+lf  l++skk+a++++++++++++ ++e    +q
   Q: 176  VGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEEAE----EDPVTSIPYQLQRLFVLLQNSKKRAIETTDVTRSFGWDSSE--AWQQ 258
           6******************************4444433....5799*********************************9998..9*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++++d+le++                           k++++ +li++l+qg+lk+ ++clec+ +  r ++ ld++l ++ 
   Q: 259  HDVQELCRVMFDALEQKW--------------------------KQTEQADLINQLYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRP 321
           ******************..........................678999*************************************95 PP
   S: 179  ke.etkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
              +++  s++++L++f ++e l+g n+y+ce+ckkk++a+k l++ ++P  L+l+LkRf f+ ++++r+k+n++++fp+eLd+s f  
   Q: 322  YGsSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMSFPEELDMSTFID 410
           54045678******************************************************************************999 PP
   S: 267  speekqke.....................................................kkkYeLiavvvHsGslssGHYvayvkne 302
            ++ek+ +                                                     +  YeL++v+vHsGs+ +GHY+a++k+ 
   Q: 411  VEDEKSPQtesctdsgaenegschsdqmsndfsnddgvdegiclesnsgtekvskpglekhSLLYELFSVMVHSGSAAGGHYYACIKSF 499
           9777776688899999999999999999999999999999999999999999999999999***************************6 PP
   S: 303  kgk.WllfdDskVtevkeeevleetg................staYvlfYk 336
           +++ W+ f+D++V+ ++ e++++++g                ++aY+l+Y+
   Q: 500  SDEqWYSFNDQHVSRITAEDIKKTHGgssgsrgyyssafassTNAYMLIYR 550
           5555*******************888************************8 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

QDMFWRCRQS IFDEMKKKFA QVENAAEEPR ILCIIQDTTN SKTANERLTL NLPASTPLKK 60
LFEDVASKLG YIYGTFDLAW GNGIVVAALP PLDHTSERSL LDNNFEPGKK NFLHLTDKEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGATATGT TTTGGAGATG CAGACAAAGT ATCTTTGATG AAATGAAGAA GAAATTTGCA 60
CAGGTAGCCA GCTGAAGTGA TAACCTGCGT ACTTAGTAAC AGCATGATAT GAACGAAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0006284--P:base-excision repair
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0016579--P:protein deubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002228	Ailuropoda melanoleuca	87.94	0.00e+00	2347.00
IUUC-Apl-003486	Anas platyrhynchos	86.01	0.00e+00	2218.00
IUUC-Aca-005061	Anolis carolinensis	84.71	0.00e+00	2280.00
IUUC-Ame-011206	Astyanax mexicanus	79.47	0.00e+00	2070.00
IUUC-Bta-012942	Bos taurus	88.44	0.00e+00	2332.00
IUUC-Cel-018600	Caenorhabditis elegans	37.41	2.00e-117	417.00
IUUC-Cja-018950	Callithrix jacchus	89.25	0.00e+00	2180.00
IUUC-Cfa-020299	Canis familiaris	89.14	0.00e+00	2355.00
IUUC-Cpo-021943	Cavia porcellus	88.14	0.00e+00	2323.00
IUUC-Csa-023285	Chlorocebus sabaeus	88.95	0.00e+00	2296.00
IUUC-Cho-025006	Choloepus hoffmanni	81.24	0.00e+00	2004.00
IUUC-Cin-025145	Ciona intestinalis	40.51	0.00e+00	709.00
IUUC-Csv-025839	Ciona savignyi	49.55	8.00e-163	567.00
IUUC-Dre-027959	Danio rerio	79.80	0.00e+00	2009.00
IUUC-Dno-030023	Dasypus novemcinctus	86.13	0.00e+00	2220.00
IUUC-Dor-030994	Dipodomys ordii	85.55	0.00e+00	849.00
IUUC-Dme-031604	Drosophila melanogaster	49.31	2.00e-142	499.00
IUUC-Ete-032596	Echinops telfairi	72.44	0.00e+00	1156.00
IUUC-Eca-033913	Equus caballus	88.82	0.00e+00	2340.00
IUUC-Eeu-034518	Erinaceus europaeus	82.03	0.00e+00	1979.00
IUUC-Fca-035997	Felis catus	88.96	0.00e+00	2378.00
IUUC-Fal-037088	Ficedula albicollis	86.76	0.00e+00	1988.00
IUUC-Gmo-038920	Gadus morhua	75.89	0.00e+00	1958.00
IUUC-Gga-040953	Gallus gallus	85.74	0.00e+00	2209.00
IUUC-Gac-042400	Gasterosteus aculeatus	77.55	0.00e+00	1970.00
IUUC-Ggo-044820	Gorilla gorilla	86.80	0.00e+00	2264.00
IUUC-Hsa-046634	Homo sapiens	88.82	0.00e+00	2329.00
IUUC-Lch-050440	Latimeria chalumnae	82.92	0.00e+00	2176.00
IUUC-Loc-051904	Lepisosteus oculatus	82.09	0.00e+00	2134.00
IUUC-Laf-053760	Loxodonta africana	88.09	0.00e+00	2349.00
IUUC-Mcc-054637	Macaca mulatta	88.89	0.00e+00	2335.00
IUUC-Meu-056904	Macropus eugenii	90.14	0.00e+00	1588.00
IUUC-Mga-059556	Meleagris gallopavo	85.06	0.00e+00	2196.00
IUUC-Mmr-061192	Microcebus murinus	88.96	0.00e+00	2341.00
IUUC-Mdo-061929	Monodelphis domestica	89.77	0.00e+00	2394.00
IUUC-Mmu-063726	Mus musculus	86.40	0.00e+00	2337.00
IUUC-Mpu-066014	Mustela putorius furo	89.18	0.00e+00	2347.00
IUUC-Mlu-067232	Myotis lucifugus	88.46	0.00e+00	2329.00
IUUC-Nle-069619	Nomascus leucogenys	88.80	0.00e+00	2291.00
IUUC-Opr-070224	Ochotona princeps	82.88	0.00e+00	1033.00
IUUC-Ont-071384	Oreochromis niloticus	79.25	0.00e+00	2009.00
IUUC-Ocu-074285	Oryctolagus cuniculus	88.74	0.00e+00	2335.00
IUUC-Ola-087051	Oryzias latipes	78.10	0.00e+00	1930.00
IUUC-Oga-088928	Otolemur garnettii	88.88	0.00e+00	2335.00
IUUC-Oar-090215	Ovis aries	88.68	0.00e+00	2343.00
IUUC-Ptr-091035	Pan troglodytes	88.74	0.00e+00	2331.00
IUUC-Pan-092377	Papio anubis	88.44	0.00e+00	2311.00
IUUC-Pfo-096722	Poecilia formosa	78.96	0.00e+00	2006.00
IUUC-Pab-098723	Pongo abelii	88.74	0.00e+00	2333.00
IUUC-Pca-100105	Procavia capensis	83.51	0.00e+00	2132.00
IUUC-Pva-102514	Pteropus vampyrus	91.25	0.00e+00	904.00
IUUC-Rno-105384	Rattus norvegicus	87.42	0.00e+00	2297.00
IUUC-Sha-106982	Sarcophilus harrisii	88.19	0.00e+00	2348.00
IUUC-Sar-113723	Sorex araneus	82.57	0.00e+00	890.00
IUUC-Ssc-115671	Sus scrofa	89.70	0.00e+00	1871.00
IUUC-Tgu-116722	Taeniopygia guttata	84.19	0.00e+00	2207.00
IUUC-Tru-118380	Takifugu rubripes	76.87	0.00e+00	2021.00
IUUC-Tsy-119646	Tarsius syrichta	82.33	0.00e+00	2122.00
IUUC-Tni-120762	Tetraodon nigroviridis	77.59	0.00e+00	2036.00
IUUC-Tbe-127861	Tupaia belangeri	86.42	0.00e+00	2144.00
IUUC-Ttr-129254	Tursiops truncatus	82.50	0.00e+00	1303.00
IUUC-Vpa-130141	Vicugna pacos	91.13	0.00e+00	1120.00
IUUC-Xtr-132700	Xenopus tropicalis	79.07	0.00e+00	2125.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence