iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047591

Ensembl Protein ID

MLOC_12166.1

UniProt Accession

F2E9J4; F2E9J4_HORVV

Genbank Protein ID

BAK04016.1

Protein Name

Predicted protein

Genbank Nucleotide ID

AK372819

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_12166	MLOC_12166.1	MLOC_12166.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-35	120.0	242	273
UBD/Beta-Prp	4.60e-51	174.8	22	321

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v +++  +d   +v+Gs D ti++WD+
   Q: 242  GHASWVLSIDVsPDgMAVVTGSSDRTIRLWDI 273
           8***********994558*************6 PP

UBD/Beta-Prp

   S: 18   f.....spdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsg.d 107
           +     ++ + ll+tgs d+t++ w+ ++  + +    gh  +v ++  +p g i + +s D +i+v+d+++g  v tl +  ++v+ ++f+p+g  
   Q: 22   WvpaadHRPTALLLTGSIDETVRAWQPDDLAVASPPaGGHALGVVSLAAHPAGVIAAAVSIDSHIRVFDVDSGASVTTLDAAPSEVWGVQFHPKGiA 118
           445445667889*****************7775555699******************************************************9989 PP
   S: 108  klvsGshdrtirvwdletgqclee...........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng. 192
             ++G+    +++wd+e+ q + +            ++g  ++v +v+++pdg+ll+ Gs D+t+ ++d  ++k l++l g h+ +v+s+ f++   
   Q: 119  LAAAGGGSGSVKLWDTEKWQPIASlpvprpegarpDKTGSGKFVLSVAWSPDGKLLACGSMDGTIAVYDAVRMKFLHHLDG-HHMPVRSMVFSPVDp 214
           99********************99**********98999*****************************************9.************883 PP
   S: 193  kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfg.....dnvlvlgs 284
             l++g +d+ + ++d +++  + ++ gh ++v+s+++sp++  +v+gssD++ir+Wd+  +  ++t+++h ++v++va+  +g        l+++s
   Q: 215  HVLLTGCDDSHIHIYDAKEKGLIGAMSGHASWVLSIDVSPDGMAVVTGSSDRTIRLWDINARASVQTMSNHSDQVWAVAFRPPGgegvrAGRLASAS 311
           5567899999**********************************************************************555533333667799** PP
   S: 285  edskvniwkl 294
           +d+++ ++++
   Q: 312  DDKSISLYDY 321
           ********98 PP

Organism

Hordeum vulgare

Protein Sequence
(Fasta)

MKLAGFKSVD GAHEDSIWAA AWVPAADHRP TALLLTGSID ETVRAWQPDD LAVASPPAGG 60
HALGVVSLAA HPAGVIAAAV SIDSHIRVFD VDSGASVTTL DAAPSEVWGV QFHPKGIALA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCTCCCA CCTCCCCTCG CCTCAGCAGC CAGATCAAAC ACCTAGGGTT TCGTTTGCGA 60
GAGAGAAGAG AGGGTACGAT GAAGCTTGCG GGGTTCAAGT CGGTGGACGG GGCTCACGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0010452--P:histone H3-K36 methylation
GO:0051568--P:histone H3-K4 methylation
GO:0009910--P:negative regulation of flower development
GO:0016441--P:posttranscriptional gene silencing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	86.42	2.00e-160	556.00
IUUC-Aml-002245	Ailuropoda melanoleuca	37.97	7.00e-49	186.00
IUUC-Atr-003142	Amborella trichopoda	65.15	1.00e-77	280.00
IUUC-Apl-003179	Anas platyrhynchos	37.66	1.00e-51	195.00
IUUC-Aca-004880	Anolis carolinensis	38.68	2.00e-57	214.00
IUUC-Aly-005956	Arabidopsis lyrata	66.56	2.00e-124	437.00
IUUC-Ath-007230	Arabidopsis thaliana	67.49	1.00e-116	411.00
IUUC-Ame-011511	Astyanax mexicanus	39.42	3.00e-54	203.00
IUUC-Bgr-012189	Blumeria graminis	29.19	1.00e-17	82.40
IUUC-Bta-012936	Bos taurus	37.97	5.00e-49	186.00
IUUC-Bdi-015020	Brachypodium distachyon	93.17	2.00e-151	526.00
IUUC-Bol-016345	Brassica oleracea	66.87	2.00e-124	437.00
IUUC-Bra-017323	Brassica rapa	66.87	1.00e-124	437.00
IUUC-Cja-019961	Callithrix jacchus	37.97	5.00e-49	186.00
IUUC-Cfa-020862	Canis familiaris	38.29	3.00e-49	187.00
IUUC-Cpo-021356	Cavia porcellus	38.29	2.00e-49	187.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	40.71	2.00e-51	194.00
IUUC-Csa-024067	Chlorocebus sabaeus	37.97	9.00e-49	185.00
IUUC-Cho-024421	Choloepus hoffmanni	35.19	2.00e-19	87.40
IUUC-Cin-025261	Ciona intestinalis	36.91	6.00e-56	209.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	28.35	2.00e-26	111.00
IUUC-Cne-026846	Cryptococcus neoformans	30.29	7.00e-24	103.00
IUUC-Dre-027706	Danio rerio	31.03	1.00e-34	139.00
IUUC-Dno-029084	Dasypus novemcinctus	38.05	1.00e-47	182.00
IUUC-Dor-030353	Dipodomys ordii	34.17	2.00e-38	151.00
IUUC-Dme-031836	Drosophila melanogaster	33.83	6.00e-51	193.00
IUUC-Ete-032261	Echinops telfairi	37.78	7.00e-49	186.00
IUUC-Eca-034231	Equus caballus	34.81	6.00e-41	159.00
IUUC-Eeu-034828	Erinaceus europaeus	37.54	4.00e-46	176.00
IUUC-Fca-036569	Felis catus	37.97	6.00e-49	186.00
IUUC-Fal-037469	Ficedula albicollis	37.97	2.00e-52	197.00
IUUC-Fox-038047	Fusarium oxysporum	26.79	2.00e-22	97.80
IUUC-Gmo-039579	Gadus morhua	41.29	3.00e-56	210.00
IUUC-Gga-040808	Gallus gallus	37.74	3.00e-51	194.00
IUUC-Gac-042100	Gasterosteus aculeatus	40.32	6.00e-55	206.00
IUUC-Gma-044408	Glycine max	69.04	4.00e-124	436.00
IUUC-Ggo-045227	Gorilla gorilla	37.97	5.00e-49	186.00
IUUC-Hsa-045839	Homo sapiens	37.97	5.00e-49	186.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	37.97	6.00e-49	186.00
IUUC-Lch-049549	Latimeria chalumnae	35.76	2.00e-48	184.00
IUUC-Lpe-050746	Leersia perrieri	87.65	1.00e-141	494.00
IUUC-Loc-052540	Lepisosteus oculatus	39.35	1.00e-50	192.00
IUUC-Laf-053907	Loxodonta africana	37.97	6.00e-49	186.00
IUUC-Mcc-055828	Macaca mulatta	35.71	1.00e-45	175.00
IUUC-Meu-056075	Macropus eugenii	40.23	5.00e-47	179.00
IUUC-Mtr-057728	Medicago truncatula	65.94	4.00e-111	392.00
IUUC-Mga-059872	Meleagris gallopavo	37.74	1.00e-51	194.00
IUUC-Mmr-060985	Microcebus murinus	37.74	3.00e-48	184.00
IUUC-Mdo-062758	Monodelphis domestica	38.49	2.00e-52	197.00
IUUC-Mmu-063580	Mus musculus	37.66	1.00e-48	185.00
IUUC-Mac-064880	Musa acuminata	74.84	3.00e-139	486.00
IUUC-Mpu-066577	Mustela putorius furo	38.17	1.00e-48	185.00
IUUC-Nle-069573	Nomascus leucogenys	37.97	5.00e-49	186.00
IUUC-Opr-070216	Ochotona princeps	38.61	4.00e-49	187.00
IUUC-Ont-071981	Oreochromis niloticus	40.51	1.00e-54	204.00
IUUC-Oan-073223	Ornithorhynchus anatinus	41.58	2.00e-38	150.00
IUUC-Ocu-074199	Oryctolagus cuniculus	35.31	3.00e-41	160.00
IUUC-Oba-075255	Oryza barthii	77.33	6.00e-122	428.00
IUUC-Obr-076168	Oryza brachyantha	91.24	4.00e-105	372.00
IUUC-Ogl-077777	Oryza glaberrima	87.31	1.00e-141	494.00
IUUC-Ogu-078780	Oryza glumaepatula	87.31	1.00e-141	494.00
IUUC-Oin-079228	Oryza indica	87.31	2.00e-145	506.00
IUUC-Olo-080617	Oryza longistaminata	90.97	3.00e-75	272.00
IUUC-Ome-081421	Oryza meridionalis	85.76	9.00e-142	494.00
IUUC-Oni-082997	Oryza nivara	87.31	2.00e-145	506.00
IUUC-Opu-083931	Oryza punctata	88.51	7.00e-147	511.00
IUUC-Oru-084645	Oryza rufipogon	87.31	1.00e-141	494.00
IUUC-Osa-085842	Oryza sativa	87.31	2.00e-145	506.00
IUUC-Ola-086696	Oryzias latipes	40.51	4.00e-52	196.00
IUUC-Olu-087643	Ostreococcus lucimarinus	47.56	4.00e-48	182.00
IUUC-Oga-088272	Otolemur garnettii	38.49	3.00e-49	187.00
IUUC-Oar-089416	Ovis aries	37.97	5.00e-49	186.00
IUUC-Ptr-090944	Pan troglodytes	37.97	5.00e-49	186.00
IUUC-Pan-091861	Papio anubis	37.97	5.00e-49	186.00
IUUC-Psi-093750	Pelodiscus sinensis	37.66	4.00e-51	193.00
IUUC-Pma-094608	Petromyzon marinus	36.53	1.00e-46	178.00
IUUC-Ppa-095737	Physcomitrella patens	61.35	2.00e-110	390.00
IUUC-Pfo-096479	Poecilia formosa	39.68	8.00e-52	196.00
IUUC-Pab-098179	Pongo abelii	37.97	5.00e-49	186.00
IUUC-Pop-099532	Populus trichocarpa	65.42	7.00e-110	388.00
IUUC-Pca-100664	Procavia capensis	33.62	1.00e-23	102.00
IUUC-Ppe-102056	Prunus persica	66.87	2.00e-120	424.00
IUUC-Pva-102859	Pteropus vampyrus	37.66	7.00e-48	182.00
IUUC-Rno-105826	Rattus norvegicus	37.66	1.00e-48	185.00
IUUC-Sha-106660	Sarcophilus harrisii	37.66	4.00e-49	186.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	27.59	2.00e-20	92.00
IUUC-Spo-108244	Schizosaccharomyces pombe	25.86	4.00e-20	90.50
IUUC-Smo-109382	Selaginella moellendorffii	55.28	2.00e-90	324.00
IUUC-Sit-110048	Setaria italica	89.44	3.00e-137	479.00
IUUC-Sly-111249	Solanum lycopersicum	60.31	9.00e-107	378.00
IUUC-Stu-112659	Solanum tuberosum	60.62	5.00e-106	375.00
IUUC-Sar-113743	Sorex araneus	38.94	1.00e-34	139.00
IUUC-Sbi-114309	Sorghum bicolor	87.89	2.00e-134	470.00
IUUC-Ssc-115560	Sus scrofa	35.76	2.00e-43	167.00
IUUC-Tgu-117300	Taeniopygia guttata	37.66	5.00e-52	196.00
IUUC-Tru-117933	Takifugu rubripes	40.00	2.00e-55	207.00
IUUC-Tsy-119574	Tarsius syrichta	31.96	1.00e-31	128.00
IUUC-Tni-120191	Tetraodon nigroviridis	40.08	5.00e-42	162.00
IUUC-Tca-120983	Theobroma cacao	66.98	5.00e-115	405.00
IUUC-Tae-122888	Triticum aestivum	96.89	5.00e-163	565.00
IUUC-Tur-126711	Triticum urartu	95.98	2.00e-160	556.00
IUUC-Tbe-127802	Tupaia belangeri	37.97	6.00e-49	186.00
IUUC-Vda-129720	Verticillium dahliae	27.22	4.00e-19	87.00
IUUC-Vpa-130618	Vicugna pacos	38.40	6.00e-42	162.00
IUUC-Vvi-130981	Vitis vinifera	68.73	8.00e-117	411.00
IUUC-Xtr-132460	Xenopus tropicalis	38.71	2.00e-51	194.00
IUUC-Xma-134154	Xiphophorus maculatus	40.51	4.00e-52	196.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence