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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Spo-108214
UUCD1 version UUC-ScP-00233
Ensembl Protein ID SPAC806.02c.1:pep
UniProt Accession Q9UT57; CFD1_SCHPO
Genbank Protein ID CAB55281.1
Protein Name Probable cytosolic Fe-S cluster assembly factor SPAC806.02c
Genbank Nucleotide ID CU329670
Gene Name SPAC806.02c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPAC806.02c SPAC806.02c.1 SPAC806.02c.1:pep
Annotation
mRNA Expression
GEO
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.40e-36 120.3 376 409
UBD/Beta-Prp 2.70e-60 202.1 274 502
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH+++v c+a+  ++++l+++s+D+++ +W+ ++
   Q: 376  GHENEVKCIAWscNGNYLATCSRDKSVWIWEATE 409
           8**********9655***************9766 PP
   

   UBD/Beta-Prp
   S: 36   vwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg.hedsvlslsfsp.sgdklvsGshdrtirv.wdle 124
           ++  ++ +++ ++sgh++  ++v  +p  ++++t+s+D+ +++++ +t+  vh++ g h++s++ +++ p ++ +l+++s d+++ +  +++
   Q: 274  LYGPRKLDTITTISGHTGRLWSVAAHPMLPLFATSSQDKSVRIYNSNTYNLVHVIDGfHTRSIRRVAWRPiERPVLAVASFDSVVSInEKID 365
           5555566669**********************************************77************777**************65678 PP
   S: 125  tgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq..t 211
            +++  + l+gh+  v c++++++gn+l+++s D+ v +W        ++l  l++ ht++v+ ++++++   lvsgs+d+++ +w      
   Q: 366  DDWECTAALEGHENEVKCIAWSCNGNYLATCSRDKSVWIWEAtedDEFDCLAVLQE-HTQDVKVVTWHPTEDLLVSGSYDNSICFWRDDgdD 456
           8888888**********************************977766689999**9.******************************99554 PP
   S: 212  gecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......d 250
                +l+ght++v+ ++fspn++ l+s+  Dg +++W       d
   Q: 457  WALTCQLQGHTNTVWALAFSPNGNTLASADNDGNVFLWikissneD 502
           44466789******************************75544443 PP
   
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Fusion protein of two essential components of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. May form a heterotetramer with nubp35, functioning as a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (By similarity).
 Fusion protein of two essential components of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. May form a heterotetramer with nubp35, functioning as a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (By similarity).
Protein Sequence
(Fasta)
MDKVQHVILV LSGKGGVGKS SVTTQLALSL HDSKVYSRPL KTGILDIDLT GPSIPRMFGK 60
DAERNRIHQS SAGWVPVYTD ETKEIGLMSL GFLLTSKNDS VVWRGPKKAA MIRQFISDVS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108214|E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATTACTAAGT AAACACAGAG TTTTTACCTT TTTCCATTTT AAACTACAAT TGCTTGTTAT 60
GGGTAAATGA TATTGAGAAG TTTTTTTTTC ATTTAATTAA CTTTATAATA GATAAAGTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108214|E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0004--4Fe-4S
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0408--Iron
KW-0411--Iron-sulfur
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR028608--CIAO1/Cia1
IPR019591--Mrp/NBP35_ATP-bd
IPR000808--Mrp_CS
IPR028600--NUBP2/Cfd1_eukaryotes
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR033756--YlxH/NBP35
PROSITE

PS01215--MRP
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF10609--ParA
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0097361--C:CIA complex
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0051539--F:4 iron, 4 sulfur cluster binding
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0046872--F:metal ion binding
GO:0016226--P:iron-sulfur cluster assembly
KEGG spo:SPAC806.02c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000874 Aegilops tauschii 40.98 1.00e-47 182.00
IUUC-Aml-001317 Ailuropoda melanoleuca 37.85 2.00e-48 183.00
IUUC-Atr-003029 Amborella trichopoda 36.47 4.00e-59 219.00
IUUC-Aly-006458 Arabidopsis lyrata 36.08 2.00e-56 210.00
IUUC-Ath-006671 Arabidopsis thaliana 36.65 1.00e-57 214.00
IUUC-Ago-007820 Ashbya gossypii 41.76 9.00e-65 238.00
IUUC-Acl-008042 Aspergillus clavatus 31.40 2.00e-51 194.00
IUUC-Afl-008639 Aspergillus flavus 32.78 8.00e-58 215.00
IUUC-Afu-008899 Aspergillus fumigatus 31.65 1.00e-52 198.00
IUUC-Ani-009453 Aspergillus nidulans 33.65 2.00e-58 217.00
IUUC-Ang-009758 Aspergillus niger 40.55 5.00e-46 176.00
IUUC-Aor-010212 Aspergillus oryzae 32.78 8.00e-58 215.00
IUUC-Ate-010314 Aspergillus terreus 33.33 1.00e-57 214.00
IUUC-Ame-010676 Astyanax mexicanus 38.17 1.00e-61 228.00
IUUC-Bgr-012095 Blumeria graminis 32.45 8.00e-46 176.00
IUUC-Bta-012884 Bos taurus 38.65 6.00e-50 189.00
IUUC-Bci-013622 Botrytis cinerea 29.93 7.00e-42 162.00
IUUC-Bdi-014614 Brachypodium distachyon 36.47 9.00e-58 215.00
IUUC-Bol-016439 Brassica oleracea 35.63 5.00e-55 206.00
IUUC-Bra-016830 Brassica rapa 35.73 1.00e-55 207.00
IUUC-Cel-018709 Caenorhabditis elegans 34.50 2.00e-44 171.00
IUUC-Cja-019822 Callithrix jacchus 38.46 8.00e-50 188.00
IUUC-Cfa-020823 Canis familiaris 37.73 1.00e-48 184.00
IUUC-Cre-022811 Chlamydomonas reinhardtii 36.24 2.00e-53 200.00
IUUC-Csa-023754 Chlorocebus sabaeus 38.15 1.00e-49 187.00
IUUC-Cin-025395 Ciona intestinalis 34.71 1.00e-51 194.00
IUUC-Csv-025943 Ciona savignyi 35.69 1.00e-52 197.00
IUUC-Cgl-026435 Colletotrichum gloeosporioides 32.37 2.00e-45 174.00
IUUC-Cne-026939 Cryptococcus neoformans 30.38 2.00e-48 184.00
IUUC-Cme-027239 Cyanidioschyzon merolae 37.09 5.00e-38 150.00
IUUC-Dre-028172 Danio rerio 38.67 4.00e-61 226.00
IUUC-Dno-029472 Dasypus novemcinctus 39.45 1.00e-44 171.00
IUUC-Dor-031134 Dipodomys ordii 38.78 1.00e-34 138.00
IUUC-Dse-031535 Dothistroma septosporum 30.09 8.00e-53 199.00
IUUC-Dme-032020 Drosophila melanogaster 38.97 4.00e-62 229.00
IUUC-Eca-033700 Equus caballus 37.54 5.00e-48 182.00
IUUC-Eeu-035010 Erinaceus europaeus 37.42 2.00e-45 173.00
IUUC-Fca-036309 Felis catus 32.62 4.00e-42 162.00
IUUC-Fal-037243 Ficedula albicollis 40.18 2.00e-37 146.00
IUUC-Fox-038058 Fusarium oxysporum 33.60 1.00e-51 195.00
IUUC-Fso-038459 Fusarium solani 30.97 5.00e-45 173.00
IUUC-Gmo-039375 Gadus morhua 38.77 6.00e-53 198.00
IUUC-Ggr-040002 Gaeumannomyces graminis 35.42 5.00e-46 176.00
IUUC-Gga-040294 Gallus gallus 42.24 6.00e-39 152.00
IUUC-Gac-042499 Gasterosteus aculeatus 39.94 3.00e-50 189.00
IUUC-Gma-043543 Glycine max 38.86 7.00e-63 231.00
IUUC-Ggo-045181 Gorilla gorilla 38.15 1.00e-49 187.00
IUUC-Hsa-046528 Homo sapiens 38.15 1.00e-49 187.00
IUUC-Hvu-047341 Hordeum vulgare 48.15 7.00e-46 174.00
IUUC-Itr-048790 Ictidomys tridecemlineatus 37.73 7.00e-49 185.00
IUUC-Kpa-049353 Komagataella pastoris 41.62 2.00e-74 270.00
IUUC-Lch-049763 Latimeria chalumnae 37.28 1.00e-49 187.00
IUUC-Lpe-051500 Leersia perrieri 35.88 8.00e-57 212.00
IUUC-Loc-052021 Lepisosteus oculatus 38.89 5.00e-50 189.00
IUUC-Lma-053331 Leptosphaeria maculans 37.97 1.00e-67 249.00
IUUC-Laf-054558 Loxodonta africana 37.73 2.00e-48 183.00
IUUC-Mcc-055374 Macaca mulatta 38.15 2.00e-49 187.00
IUUC-Meu-056042 Macropus eugenii 44.71 5.00e-39 152.00
IUUC-Mor-057187 Magnaporthe oryzae 33.65 6.00e-51 192.00
IUUC-Mtr-058072 Medicago truncatula 37.43 4.00e-60 222.00
IUUC-Mla-059108 Melampsora laricipopulina 29.84 1.00e-44 171.00
IUUC-Mga-059370 Meleagris gallopavo 40.00 1.00e-23 101.00
IUUC-Mvi-060495 Microbotryum violaceum 34.05 9.00e-50 189.00
IUUC-Mmr-060902 Microcebus murinus 37.73 5.00e-49 186.00
IUUC-Mdo-062510 Monodelphis domestica 42.22 2.00e-46 177.00
IUUC-Mmu-063575 Mus musculus 37.23 7.00e-48 182.00
IUUC-Mac-065322 Musa acuminata 36.72 2.00e-61 227.00
IUUC-Mpu-065925 Mustela putorius furo 37.73 2.00e-48 183.00
IUUC-Mlu-067755 Myotis lucifugus 38.65 2.00e-49 187.00
IUUC-Nfi-068327 Neosartorya fischeri 31.82 5.00e-53 199.00
IUUC-Ncr-068845 Neurospora crassa 30.34 4.00e-42 163.00
IUUC-Nle-069406 Nomascus leucogenys 37.23 5.00e-46 176.00
IUUC-Opr-070416 Ochotona princeps 46.50 3.00e-27 113.00
IUUC-Ont-071936 Oreochromis niloticus 39.05 2.00e-51 194.00
IUUC-Oan-073452 Ornithorhynchus anatinus 45.35 5.00e-32 128.00
IUUC-Ocu-074791 Oryctolagus cuniculus 37.61 4.00e-50 189.00
IUUC-Oba-075636 Oryza barthii 37.72 3.00e-59 219.00
IUUC-Obr-076742 Oryza brachyantha 39.25 2.00e-53 200.00
IUUC-Ogl-077766 Oryza glaberrima 37.72 3.00e-59 219.00
IUUC-Ogu-079039 Oryza glumaepatula 37.43 4.00e-58 216.00
IUUC-Oin-079315 Oryza indica 38.91 1.00e-52 198.00
IUUC-Olo-080669 Oryza longistaminata 35.43 1.00e-53 201.00
IUUC-Ome-081490 Oryza meridionalis 37.72 2.00e-59 220.00
IUUC-Oni-082572 Oryza nivara 37.72 3.00e-59 219.00
IUUC-Opu-083732 Oryza punctata 37.43 1.00e-58 218.00
IUUC-Oru-084763 Oryza rufipogon 37.72 3.00e-59 219.00
IUUC-Osa-085372 Oryza sativa 37.72 3.00e-59 219.00
IUUC-Ola-087379 Oryzias latipes 39.17 2.00e-50 190.00
IUUC-Olu-087801 Ostreococcus lucimarinus 33.24 1.00e-37 148.00
IUUC-Oga-089076 Otolemur garnettii 37.73 8.00e-49 185.00
IUUC-Oar-090022 Ovis aries 38.34 2.00e-49 187.00
IUUC-Ptr-090809 Pan troglodytes 38.15 1.00e-49 187.00
IUUC-Pan-091685 Papio anubis 38.15 3.00e-50 191.00
IUUC-Psi-093046 Pelodiscus sinensis 36.62 2.00e-46 177.00
IUUC-Pma-094181 Petromyzon marinus 41.20 8.00e-58 215.00
IUUC-Pno-094882 Phaeosphaeria nodorum 34.94 3.00e-61 226.00
IUUC-Ppa-095172 Physcomitrella patens 35.43 9.00e-52 195.00
IUUC-Pfo-096396 Poecilia formosa 38.76 3.00e-51 193.00
IUUC-Pab-098427 Pongo abelii 37.96 2.00e-49 187.00
IUUC-Pop-100016 Populus trichocarpa 38.07 3.00e-61 226.00
IUUC-Pca-101048 Procavia capensis 38.04 1.00e-48 184.00
IUUC-Ppe-102050 Prunus persica 37.18 5.00e-61 226.00
IUUC-Pva-103117 Pteropus vampyrus 37.35 2.00e-48 183.00
IUUC-Pgr-103307 Puccinia graminis 33.61 3.00e-45 174.00
IUUC-Ptt-103938 Puccinia triticina 33.53 3.00e-39 153.00
IUUC-Pte-104315 Pyrenophora teres 36.91 4.00e-67 246.00
IUUC-Pyt-104825 Pyrenophora triticirepentis 36.16 2.00e-66 244.00
IUUC-Rno-105523 Rattus norvegicus 37.23 4.00e-48 182.00
IUUC-Sce-106297 Saccharomyces cerevisiae 39.07 3.00e-59 219.00
IUUC-Sha-106981 Sarcophilus harrisii 45.18 4.00e-42 162.00
IUUC-Sja-107715 Schizosaccharomyces japonicus 67.87 0.00e+00 835.00
IUUC-Smo-109034 Selaginella moellendorffii 38.38 1.00e-55 207.00
IUUC-Sit-110663 Setaria italica 35.86 5.00e-57 212.00
IUUC-Sly-110898 Solanum lycopersicum 34.96 3.00e-53 200.00
IUUC-Stu-112647 Solanum tuberosum 39.13 2.00e-51 193.00
IUUC-Sbi-114288 Sorghum bicolor 36.06 1.00e-57 214.00
IUUC-Sre-115065 Sporisorium reilianum 33.41 6.00e-61 226.00
IUUC-Ssc-115960 Sus scrofa 35.28 1.00e-51 194.00
IUUC-Tru-118382 Takifugu rubripes 39.47 7.00e-62 228.00
IUUC-Tsy-119585 Tarsius syrichta 35.19 6.00e-42 162.00
IUUC-Tni-120133 Tetraodon nigroviridis 37.39 1.00e-53 201.00
IUUC-Tca-121167 Theobroma cacao 35.47 1.00e-55 207.00
IUUC-Tre-122119 Trichoderma reesei 28.61 2.00e-41 161.00
IUUC-Tvi-122407 Trichoderma virens 30.70 1.00e-44 171.00
IUUC-Tae-124500 Triticum aestivum 35.80 1.00e-56 211.00
IUUC-Tur-126682 Triticum urartu 38.15 2.00e-49 186.00
IUUC-Tme-127095 Tuber melanosporum 39.27 2.00e-73 267.00
IUUC-Tbe-128004 Tupaia belangeri 38.15 1.00e-48 184.00
IUUC-Ttr-129284 Tursiops truncatus 37.39 5.00e-45 172.00
IUUC-Uma-129527 Ustilago maydis 34.03 9.00e-61 225.00
IUUC-Vda-129854 Verticillium dahliae 31.37 2.00e-46 177.00
IUUC-Vpa-130681 Vicugna pacos 58.10 1.00e-22 98.20
IUUC-Vvi-131004 Vitis vinifera 38.37 2.00e-60 223.00
IUUC-Xtr-131928 Xenopus tropicalis 35.80 5.00e-47 179.00
IUUC-Xma-134290 Xiphophorus maculatus 38.46 2.00e-50 190.00
IUUC-Yli-134364 Yarrowia lipolytica 46.73 3.00e-82 296.00
IUUC-Zma-135658 Zea mays 36.52 4.00e-56 209.00
Created Date 25-Jun-2017

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