iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098511

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Sentrin-specific protease 2

Genbank Nucleotide ID

ABGA01003357

Gene Name

SENP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000014368.2	ENSPPYT00000016714.2	ENSPPYP00000016070.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/ULP	3.10e-55	187.1	381	543

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/ULP

   S: 2    svtnedlkcLeegeflnDviidfylkylvleklkkekverihifssffykklkqkerrrvktwtrkvdlfekdlifvpineaaHWslav 90
            +t+ d+++L++ ++lnD++i+fy++ l++e+ kk+ ++ +h+fs+ffy klk+ ++++vk+wt+ v+lfe+++i+vpi++++HWsl+v
   Q: 381  RITRGDIQTLKNYHWLNDEVINFYMN-LLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVV 468
           699***********************.999*********************************************************** PP
   S: 91   vcfkkksilllDSlrgasksnvvkklreylevevkkkskrefskeklkgsnpk...vpqQkNssDCGvyvlqyves 163
           ++++kk++ +lDS+ g++ ++++++l +yl++e+k+k++++++  ++ ++++k   +pqQ N+sDCG++ ++y+++
   Q: 469  IDLRKKCLKYLDSM-GQKGHRICEILLQYLQDESKTKRNIDLNLLEWTHYSMKpheIPQQLNGSDCGMFTCKYADY 543
           **************.********************************999988889*****************986 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MELSGRAGGG DVRSGGGWGP LVALGTLYLW ALESRHKSAT ELWRRWLRRR RRQRRRQLWG 60
LRLGVCRPPL LLGPGMYRWL VRILGTIFRF CDRSVPPARA LLKRRRSDST LFSTVDTDEI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCGTGCGC AGATTGAGAA TGGAGCTTTC CGGTCGGGCG GGAGGAGGTG ACGTCAGGAG 60
CGGTGGCGGG TGGGGGCCTC TGGTAGCCCT GGGGACGCTG TATCTGTGGG CTCTTGAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003653--Peptidase_C48_C

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0005643--C:nuclear pore
GO:0016605--C:PML body
GO:0016929--F:SUMO-specific protease activity
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0060711--P:labyrinthine layer development
GO:0035562--P:negative regulation of chromatin binding
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0031397--P:negative regulation of protein ubiquitination
GO:0031398--P:positive regulation of protein ubiquitination
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0031648--P:protein destabilization
GO:0016926--P:protein desumoylation
GO:0032875--P:regulation of DNA endoreduplication
GO:2000045--P:regulation of G1/S transition of mitotic cell cycle
GO:0060712--P:spongiotrophoblast layer development
GO:0060707--P:trophoblast giant cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001512	Ailuropoda melanoleuca	93.15	2.00e-154	539.00
IUUC-Apl-003602	Anas platyrhynchos	60.73	5.00e-99	354.00
IUUC-Aca-004819	Anolis carolinensis	60.58	9.00e-96	343.00
IUUC-Bta-013157	Bos taurus	93.17	6.00e-154	537.00
IUUC-Cja-018720	Callithrix jacchus	97.61	9.00e-162	563.00
IUUC-Cfa-020805	Canis familiaris	94.18	8.00e-156	543.00
IUUC-Cpo-021808	Cavia porcellus	94.20	3.00e-167	582.00
IUUC-Cre-022877	Chlamydomonas reinhardtii	31.25	4.00e-17	80.50
IUUC-Cho-024783	Choloepus hoffmanni	58.80	4.00e-140	491.00
IUUC-Cgl-026530	Colletotrichum gloeosporioides	25.43	5.00e-14	73.60
IUUC-Dno-028882	Dasypus novemcinctus	93.86	9.00e-156	543.00
IUUC-Dor-030693	Dipodomys ordii	82.12	4.00e-107	381.00
IUUC-Ete-032724	Echinops telfairi	68.94	7.00e-115	407.00
IUUC-Eca-034052	Equus caballus	94.54	6.00e-157	547.00
IUUC-Eeu-034465	Erinaceus europaeus	91.47	6.00e-150	524.00
IUUC-Fca-036319	Felis catus	93.84	5.00e-157	547.00
IUUC-Fal-037347	Ficedula albicollis	59.28	5.00e-80	290.00
IUUC-Gga-041045	Gallus gallus	58.74	2.00e-92	333.00
IUUC-Ggo-044694	Gorilla gorilla	91.13	2.00e-145	509.00
IUUC-Hsa-045920	Homo sapiens	98.29	2.00e-161	562.00
IUUC-Itr-048799	Ictidomys tridecemlineatus	94.20	3.00e-156	545.00
IUUC-Lma-052978	Leptosphaeria maculans	34.39	6.00e-20	92.40
IUUC-Laf-053368	Loxodonta africana	92.83	5.00e-154	537.00
IUUC-Mcc-055057	Macaca mulatta	97.27	3.00e-159	555.00
IUUC-Meu-056435	Macropus eugenii	72.70	1.00e-122	433.00
IUUC-Mmr-061684	Microcebus murinus	94.88	3.00e-159	555.00
IUUC-Mdo-062858	Monodelphis domestica	71.67	2.00e-117	415.00
IUUC-Mmu-063498	Mus musculus	89.76	2.00e-147	515.00
IUUC-Mpu-066611	Mustela putorius furo	93.20	5.00e-155	541.00
IUUC-Mlu-068145	Myotis lucifugus	71.13	0.00e+00	637.00
IUUC-Nle-069443	Nomascus leucogenys	99.32	3.00e-163	568.00
IUUC-Opr-070806	Ochotona princeps	74.40	2.00e-126	446.00
IUUC-Oan-073590	Ornithorhynchus anatinus	64.29	3.00e-39	155.00
IUUC-Ocu-073901	Oryctolagus cuniculus	93.86	1.00e-157	549.00
IUUC-Oga-089135	Otolemur garnettii	96.25	9.00e-158	550.00
IUUC-Oar-089942	Ovis aries	93.17	9.00e-155	540.00
IUUC-Ptr-090705	Pan troglodytes	98.63	4.00e-162	564.00
IUUC-Pan-092887	Papio anubis	96.93	1.00e-158	552.00
IUUC-Psi-093140	Pelodiscus sinensis	71.06	7.00e-114	404.00
IUUC-Pno-094805	Phaeosphaeria nodorum	34.81	1.00e-20	95.50
IUUC-Pca-100253	Procavia capensis	73.72	7.00e-114	404.00
IUUC-Ppe-101189	Prunus persica	41.08	9.00e-33	134.00
IUUC-Pva-103179	Pteropus vampyrus	94.20	6.00e-157	547.00
IUUC-Pte-104020	Pyrenophora teres	32.91	2.00e-17	84.00
IUUC-Pyt-104575	Pyrenophora triticirepentis	31.65	4.00e-18	86.70
IUUC-Rno-105258	Rattus norvegicus	89.42	6.00e-147	514.00
IUUC-Sar-113372	Sorex araneus	89.08	2.00e-134	472.00
IUUC-Ssc-115700	Sus scrofa	93.86	1.00e-149	523.00
IUUC-Tgu-117433	Taeniopygia guttata	59.55	1.00e-79	288.00
IUUC-Tsy-118960	Tarsius syrichta	75.77	2.00e-113	402.00
IUUC-Tbe-127893	Tupaia belangeri	56.79	6.00e-81	295.00
IUUC-Ttr-128910	Tursiops truncatus	94.20	3.00e-156	545.00
IUUC-Vda-129779	Verticillium dahliae	24.19	5.00e-10	59.70
IUUC-Vpa-130290	Vicugna pacos	93.17	2.00e-165	575.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence