iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033400

UUCD1 version

UUC-EqC-00962

Ensembl Protein ID

ENSECAP00000021239.1

UniProt Accession

F6YN84; F6YN84_HORSE

Protein Name

Uncharacterized protein

Gene Name

UBE2U

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000023839.1	ENSECAT00000025532.1	ENSECAP00000021239.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.00e-35	122.6	9	143

Active Site

Position(s)	Description	Evidence
89	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkee 89
           l+k++ el++++ +gi a pv+e dl ewe++i+G ++t+++g  F+l+i+f+++Y+f PP+vkf t  fhPnv+   G+ C+++l+++
   Q: 9    LEKDFLELKENNYPGIAAFPVSE-DLLEWEAEIEGLQNTIWHGLPFQLTINFTPEYNFVPPTVKFRTIPFHPNVDLYtGRPCIDFLDNP 96
           6899*******************.9**************************************************999*********** PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkk 136
           +kWs+ ++++s+ll++q +l++p  e+p+n eaa++l kn+++y+ +
   Q: 97   DKWSTSYTLSSILLTLQVMLSNPVLENPVNLEAAQILIKNEHMYSLI 143
           ******************************************99865 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MHCRAYFLLE KDFLELKENN YPGIAAFPVS EDLLEWEAEI EGLQNTIWHG LPFQLTINFT 60
PEYNFVPPTV KFRTIPFHPN VDLYTGRPCI DFLDNPDKWS TSYTLSSILL TLQVMLSNPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACTGCA GAGCCTACTT CTTGCTGGAG AAAGACTTCC TGGAGTTGAA GGAGAACAAT 60
TATCCGGTCA GTACTGGGGA CCTGAGGGAC GTGTTTCATC GGGGTACAGA TTTCTGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0016574--P:histone ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002211	Ailuropoda melanoleuca	72.18	5.00e-47	180.00
IUUC-Aca-004682	Anolis carolinensis	53.42	2.00e-39	155.00
IUUC-Bta-013054	Bos taurus	72.90	4.00e-66	244.00
IUUC-Cja-018784	Callithrix jacchus	65.81	2.00e-54	205.00
IUUC-Cfa-020877	Canis familiaris	79.35	1.00e-71	261.00
IUUC-Cpo-022462	Cavia porcellus	63.91	5.00e-49	186.00
IUUC-Csa-023486	Chlorocebus sabaeus	72.90	2.00e-64	238.00
IUUC-Cho-024685	Choloepus hoffmanni	58.57	4.00e-31	128.00
IUUC-Dno-029061	Dasypus novemcinctus	74.34	3.00e-59	221.00
IUUC-Ete-032233	Echinops telfairi	71.68	7.00e-47	179.00
IUUC-Fca-035778	Felis catus	77.42	1.00e-67	249.00
IUUC-Ggo-044718	Gorilla gorilla	72.90	4.00e-64	238.00
IUUC-Hsa-046798	Homo sapiens	73.55	9.00e-65	239.00
IUUC-Lch-050337	Latimeria chalumnae	60.27	9.00e-49	187.00
IUUC-Loc-051819	Lepisosteus oculatus	55.56	4.00e-39	155.00
IUUC-Laf-054536	Loxodonta africana	75.97	1.00e-67	249.00
IUUC-Mcc-055028	Macaca mulatta	72.90	5.00e-64	237.00
IUUC-Mmr-061623	Microcebus murinus	69.03	2.00e-51	195.00
IUUC-Mdo-062614	Monodelphis domestica	53.64	4.00e-41	161.00
IUUC-Mmu-063194	Mus musculus	59.46	4.00e-45	175.00
IUUC-Mpu-066467	Mustela putorius furo	74.84	5.00e-59	221.00
IUUC-Mlu-067976	Myotis lucifugus	72.37	1.00e-54	206.00
IUUC-Nle-069407	Nomascus leucogenys	68.39	5.00e-60	224.00
IUUC-Opr-070526	Ochotona princeps	74.76	5.00e-33	134.00
IUUC-Oan-073005	Ornithorhynchus anatinus	55.86	2.00e-35	141.00
IUUC-Ocu-074953	Oryctolagus cuniculus	72.26	1.00e-57	216.00
IUUC-Oga-089061	Otolemur garnettii	72.90	3.00e-66	244.00
IUUC-Oar-090147	Ovis aries	72.90	3.00e-66	244.00
IUUC-Ptr-090873	Pan troglodytes	73.55	7.00e-65	240.00
IUUC-Pan-091873	Papio anubis	73.55	8.00e-65	239.00
IUUC-Psi-093780	Pelodiscus sinensis	58.11	5.00e-14	71.20
IUUC-Pab-098662	Pongo abelii	73.55	8.00e-65	239.00
IUUC-Pca-100167	Procavia capensis	70.80	5.00e-47	181.00
IUUC-Rno-105522	Rattus norvegicus	53.06	1.00e-43	170.00
IUUC-Sar-113070	Sorex araneus	57.03	2.00e-35	141.00
IUUC-Ssc-115890	Sus scrofa	76.47	7.00e-67	247.00
IUUC-Tsy-119341	Tarsius syrichta	63.28	3.00e-43	168.00
IUUC-Tbe-127433	Tupaia belangeri	50.65	5.00e-30	124.00
IUUC-Ttr-128614	Tursiops truncatus	73.79	2.00e-44	172.00
IUUC-Vpa-130777	Vicugna pacos	73.55	1.00e-65	243.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence