iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004933

Ensembl Protein ID

ENSACAP00000023411.1

UniProt Accession

R4GDF3; R4GDF3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000008157.3	ENSACAT00000030830.1	ENSACAP00000023411.1
ENSACAG00000008157.3	ENSACAT00000008238.2	ENSACAP00000008066.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.40e-29	98.5	768	805
UBD/Beta-Prp	6.10e-46	156.9	682	842

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H d vt+la  ++  +l sGs+D++i++W+l + ++++
   Q: 768  HLDAVTSLAVdPNgLYLMSGSHDCSIRLWNLESKTCIQ 805
           99*********77799***************9999987 PP

UBD/Beta-Prp

   S: 15   cvkf.spdksllatgsrdgtikvwdvttgkllrslsgheae.......vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghed 95
           +v+  s d +++++++ +g + +++++t + + +l+++ ++       ++ v  +p+ +i +t++eDr+ik +d +tgk +h++ +h d
   Q: 682  SVDLvSSDPNHMVASFNSGHTCIFNMETRQRILTLESDVDTvvtsscqINKVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVAHLD 770
           4555588999*************************999999666666666666777777****************************** PP
   S: 96   svlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlW 164
            v+sl+++p+g +l sGshd  ir+w+le+++c++e     ++hd+++  v++hp++++++s+++D   +++
   Q: 771  AVTSLAVDPNGLYLMSGSHDCSIRLWNLESKTCIQEftaHRKKHDESIHDVAFHPTKCYIASAGADALAKVF 842
           ************************************999999************************988887 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MDEQAGPGVF FSNNNNNNAL LLPPPPASSS QAGAEPGEAA AAAAAAAAVA AAGGVAGPPS 60
SSSSSPSSGA AVPASAARAQ YSVPGILHFL QHEWGRFEAE RAEWEAERAE LQAQIAFLQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGAAC AGGCGGGGCC CGGCGTCTTC TTCAGCAACA ACAACAACAA CAACGCGCTG 60
CTCCTGCCGC CGCCGCCCGC TTCCTCCTCT CAGGCCGGGG CTGAGCCCGG GGAGGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

KEGG

acs:100557274

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	81.68	0.00e+00	1196.00
IUUC-Apl-003927	Anas platyrhynchos	85.83	0.00e+00	1126.00
IUUC-Afl-008585	Aspergillus flavus	26.21	8.00e-32	132.00
IUUC-Aor-009982	Aspergillus oryzae	26.21	1.00e-31	131.00
IUUC-Ate-010457	Aspergillus terreus	25.91	7.00e-30	125.00
IUUC-Ame-010997	Astyanax mexicanus	71.43	0.00e+00	996.00
IUUC-Bta-013077	Bos taurus	81.68	0.00e+00	1179.00
IUUC-Cja-018973	Callithrix jacchus	82.46	0.00e+00	1185.00
IUUC-Cfa-020988	Canis familiaris	78.01	0.00e+00	1101.00
IUUC-Cpo-022496	Cavia porcellus	81.68	0.00e+00	1191.00
IUUC-Csa-023829	Chlorocebus sabaeus	82.07	0.00e+00	1183.00
IUUC-Dre-028560	Danio rerio	67.87	0.00e+00	916.00
IUUC-Dor-030721	Dipodomys ordii	73.95	0.00e+00	1055.00
IUUC-Eca-033760	Equus caballus	81.28	0.00e+00	1138.00
IUUC-Eeu-034953	Erinaceus europaeus	88.02	0.00e+00	697.00
IUUC-Fca-036530	Felis catus	81.42	0.00e+00	1161.00
IUUC-Fal-037353	Ficedula albicollis	91.40	0.00e+00	983.00
IUUC-Gmo-039094	Gadus morhua	67.81	0.00e+00	646.00
IUUC-Gga-040132	Gallus gallus	85.86	0.00e+00	1139.00
IUUC-Gac-041705	Gasterosteus aculeatus	68.77	0.00e+00	994.00
IUUC-Ggo-045455	Gorilla gorilla	72.40	0.00e+00	1003.00
IUUC-Hsa-046415	Homo sapiens	81.94	0.00e+00	1180.00
IUUC-Lch-050475	Latimeria chalumnae	79.63	0.00e+00	1149.00
IUUC-Loc-051859	Lepisosteus oculatus	76.36	0.00e+00	1098.00
IUUC-Laf-053537	Loxodonta africana	81.68	0.00e+00	1212.00
IUUC-Mcc-055817	Macaca mulatta	82.07	0.00e+00	1183.00
IUUC-Meu-055946	Macropus eugenii	60.94	0.00e+00	763.00
IUUC-Mla-058988	Melampsora laricipopulina	36.41	2.00e-66	247.00
IUUC-Mga-059694	Meleagris gallopavo	84.99	0.00e+00	1114.00
IUUC-Mmr-060768	Microcebus murinus	82.46	0.00e+00	1187.00
IUUC-Mdo-061901	Monodelphis domestica	85.73	0.00e+00	1222.00
IUUC-Mmu-064154	Mus musculus	80.63	0.00e+00	1170.00
IUUC-Mpu-065827	Mustela putorius furo	85.21	0.00e+00	1249.00
IUUC-Mlu-067102	Myotis lucifugus	81.54	0.00e+00	1175.00
IUUC-Ncr-068831	Neurospora crassa	39.60	3.00e-22	100.00
IUUC-Nle-070008	Nomascus leucogenys	82.10	0.00e+00	1145.00
IUUC-Ont-072025	Oreochromis niloticus	71.32	0.00e+00	990.00
IUUC-Oan-072950	Ornithorhynchus anatinus	82.93	0.00e+00	1106.00
IUUC-Ocu-074316	Oryctolagus cuniculus	81.15	0.00e+00	1125.00
IUUC-Ola-087279	Oryzias latipes	68.39	0.00e+00	945.00
IUUC-Oga-088284	Otolemur garnettii	81.81	0.00e+00	1201.00
IUUC-Oar-090304	Ovis aries	81.54	0.00e+00	1178.00
IUUC-Ptr-091052	Pan troglodytes	82.07	0.00e+00	1182.00
IUUC-Pan-092270	Papio anubis	78.85	0.00e+00	1147.00
IUUC-Psi-093907	Pelodiscus sinensis	84.99	0.00e+00	1044.00
IUUC-Pfo-097042	Poecilia formosa	69.81	0.00e+00	1049.00
IUUC-Pab-098110	Pongo abelii	82.07	0.00e+00	1182.00
IUUC-Pca-100266	Procavia capensis	68.23	0.00e+00	818.00
IUUC-Pva-102824	Pteropus vampyrus	79.84	0.00e+00	1144.00
IUUC-Pgr-103483	Puccinia graminis	37.86	3.00e-58	220.00
IUUC-Rno-105638	Rattus norvegicus	80.76	0.00e+00	1178.00
IUUC-Sha-107004	Sarcophilus harrisii	78.40	0.00e+00	1044.00
IUUC-Ssc-115280	Sus scrofa	82.07	0.00e+00	1183.00
IUUC-Tgu-116759	Taeniopygia guttata	85.95	0.00e+00	1142.00
IUUC-Tru-117944	Takifugu rubripes	71.06	0.00e+00	978.00
IUUC-Tsy-119405	Tarsius syrichta	72.50	0.00e+00	955.00
IUUC-Tni-120571	Tetraodon nigroviridis	70.36	0.00e+00	987.00
IUUC-Uma-129659	Ustilago maydis	34.70	5.00e-64	239.00
IUUC-Vpa-130294	Vicugna pacos	81.40	0.00e+00	1129.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence