iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-072950

Ensembl Protein ID

ENSOANP00000015062.1

UniProt Accession

F6YDG6; F6YDG6_ORNAN

Genbank Protein ID

ENSOANP00000015062

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01174115

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000009481.2	ENSOANT00000015065.1	ENSOANP00000015062.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-30	102.5	593	630
UBD/Beta-Prp	1.40e-46	159.3	449	665

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H d vt+la  ++  +l sGs+D++i++W+l + ++++
   Q: 593  HLDAVTSLAVdPNgLYLMSGSHDCSIRLWNLESKTCIQ 630
           99*********77799***************9999987 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls......lsfspsgdklvsGshdrtirvwdletg 126
           l   l gh+++v+ + +s   + l+++s D+t+++w+     +  ++ + ++++        +s++p  +++v+  +     ++++et+
   Q: 449  LRGALLGHTDAVWGLAYSGAHQRLLSCSADGTLRLWNTAEMAPALSVFNDNQELGIpasvdlVSSDP--SHMVASFNNGCTSIFNMETR 535
           44568*******************************8887777776665666665433311155555..99999999999********* PP
   S: 127  qclee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           q + +      + + ++  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h d+v+sl++d+ng +l+sgs+d +++lw+l
   Q: 536  QRVLTlesnvdPTATTSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLDAVTSLAVDPNGLYLMSGSHDCSIRLWNL 623
           *****99999988888889999999**99**************************98.******************************* PP
   S: 210  qtgecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 624  ESKTCIQEFTAHRkkfdESIHDVAFHPSKCYIASAGADALAK 665
           *************999999******************97665 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

RAKYHKLKYG TELNQGDMKP PSYDSDEGNE TEVQPQQNSQ LMWKQGRQLL RQYLQEVGYT 60
DTILDVKSKR VRVLLGLSND VTDREEDKNQ ESVVNGTEAE IKETVMIGKP ELTDSASVLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGCCAAGT ATCACAAGTT GAAATATGGG ACGGAGTTGA ATCAAGGAGA TATGAAGCCT 60
CCGAGTTATG ATTCTGGTGA GTAACTGTAG AAGAAAGTTT TCTTTGAAAT GGATAATTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	91.32	0.00e+00	1145.00
IUUC-Apl-003927	Anas platyrhynchos	88.77	0.00e+00	1052.00
IUUC-Aca-004933	Anolis carolinensis	81.92	0.00e+00	1077.00
IUUC-Ame-010997	Astyanax mexicanus	74.30	0.00e+00	909.00
IUUC-Bta-013077	Bos taurus	91.62	0.00e+00	1144.00
IUUC-Cja-018973	Callithrix jacchus	92.37	0.00e+00	1152.00
IUUC-Cfa-020988	Canis familiaris	88.02	0.00e+00	1091.00
IUUC-Cpo-022496	Cavia porcellus	90.72	0.00e+00	1152.00
IUUC-Csa-023829	Chlorocebus sabaeus	91.77	0.00e+00	1144.00
IUUC-Dre-028560	Danio rerio	69.35	0.00e+00	827.00
IUUC-Dno-029742	Dasypus novemcinctus	85.63	0.00e+00	1090.00
IUUC-Dor-030721	Dipodomys ordii	81.89	0.00e+00	1009.00
IUUC-Eca-033760	Equus caballus	91.32	0.00e+00	1139.00
IUUC-Eeu-034953	Erinaceus europaeus	92.71	0.00e+00	728.00
IUUC-Fca-036530	Felis catus	91.62	0.00e+00	1150.00
IUUC-Fal-037353	Ficedula albicollis	83.14	0.00e+00	885.00
IUUC-Gmo-039094	Gadus morhua	69.35	6.00e-155	540.00
IUUC-Gga-040132	Gallus gallus	88.92	0.00e+00	1041.00
IUUC-Gac-041713	Gasterosteus aculeatus	73.94	0.00e+00	914.00
IUUC-Ggo-045455	Gorilla gorilla	81.25	0.00e+00	957.00
IUUC-Hsa-046415	Homo sapiens	91.62	0.00e+00	1145.00
IUUC-Lch-050475	Latimeria chalumnae	84.63	0.00e+00	1044.00
IUUC-Loc-051859	Lepisosteus oculatus	79.50	0.00e+00	985.00
IUUC-Laf-053537	Loxodonta africana	91.77	0.00e+00	1164.00
IUUC-Mcc-055817	Macaca mulatta	91.77	0.00e+00	1144.00
IUUC-Meu-055946	Macropus eugenii	68.49	0.00e+00	731.00
IUUC-Mga-059694	Meleagris gallopavo	88.77	0.00e+00	1040.00
IUUC-Mmr-060768	Microcebus murinus	91.92	0.00e+00	1149.00
IUUC-Mdo-061901	Monodelphis domestica	87.23	0.00e+00	1131.00
IUUC-Mmu-064154	Mus musculus	90.57	0.00e+00	1137.00
IUUC-Mpu-065827	Mustela putorius furo	85.94	0.00e+00	1135.00
IUUC-Mlu-067102	Myotis lucifugus	90.72	0.00e+00	1132.00
IUUC-Ncr-068831	Neurospora crassa	39.60	3.00e-22	100.00
IUUC-Nle-070008	Nomascus leucogenys	92.07	0.00e+00	1149.00
IUUC-Opr-071067	Ochotona princeps	60.31	3.00e-160	557.00
IUUC-Ont-072025	Oreochromis niloticus	74.78	0.00e+00	900.00
IUUC-Ocu-074316	Oryctolagus cuniculus	91.63	0.00e+00	1134.00
IUUC-Ola-087279	Oryzias latipes	71.75	0.00e+00	878.00
IUUC-Oga-088284	Otolemur garnettii	91.62	0.00e+00	1148.00
IUUC-Oar-090304	Ovis aries	91.92	0.00e+00	1147.00
IUUC-Ptr-091052	Pan troglodytes	91.77	0.00e+00	1147.00
IUUC-Pan-092270	Papio anubis	88.36	0.00e+00	1107.00
IUUC-Psi-093907	Pelodiscus sinensis	89.22	0.00e+00	1028.00
IUUC-Pfo-097042	Poecilia formosa	74.08	0.00e+00	978.00
IUUC-Pab-098110	Pongo abelii	91.77	0.00e+00	1147.00
IUUC-Pca-100266	Procavia capensis	78.94	0.00e+00	775.00
IUUC-Pva-102824	Pteropus vampyrus	89.52	0.00e+00	1098.00
IUUC-Pgr-103483	Puccinia graminis	37.86	5.00e-58	219.00
IUUC-Rno-105638	Rattus norvegicus	91.02	0.00e+00	1147.00
IUUC-Sha-107004	Sarcophilus harrisii	87.03	0.00e+00	1046.00
IUUC-Sre-115115	Sporisorium reilianum	34.63	5.00e-65	242.00
IUUC-Ssc-115280	Sus scrofa	92.37	0.00e+00	1155.00
IUUC-Tgu-116759	Taeniopygia guttata	88.47	0.00e+00	1060.00
IUUC-Tru-117944	Takifugu rubripes	74.34	0.00e+00	905.00
IUUC-Tsy-119405	Tarsius syrichta	83.02	0.00e+00	952.00
IUUC-Tni-120571	Tetraodon nigroviridis	74.19	0.00e+00	915.00
IUUC-Uma-129659	Ustilago maydis	35.29	3.00e-65	243.00
IUUC-Vpa-130294	Vicugna pacos	91.02	0.00e+00	1131.00
IUUC-Xtr-132253	Xenopus tropicalis	70.00	0.00e+00	756.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence