iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074205

UUCD1 version

UUC-OrC-00719

Ensembl Protein ID

ENSOCUP00000018378.1

UniProt Accession

G1TN11; G1TN11_RABIT

Protein Name

Uncharacterized protein

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015285.3	ENSOCUT00000023452.1	ENSOCUP00000018378.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.80e-30	101.5	423	462
UBD/Beta-Prp	4.20e-63	213.3	332	622

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 423  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 462
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvht 89
            +++++h++ +++v+fsp+++llatg++d+++k+w+++  k+    slsg +a++t+++f++ g++l+ +s+D + ++w ++++   ht
   Q: 332  LCVFDAHDGEVNAVQFSPGSRLLATGGMDRKVKLWEAFGDKCefKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHT 420
           57899************************************9989******************************************** PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           l+gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd+++++++r+++  
   Q: 421  LTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRSETIVREME-- 503
           *****************************************9999988....888888889*************************6.. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
             ++++ l+++++++el+s+s+d  +k++dl+++ + +t+ +      +  ++v fsp++ ++  gs+Dgs+++W + +g++ ++l+++
   Q: 504  LLGKITALDLNPERTELLSCSRDDLLKVVDLRANAVRQTFSAPGfkcgSDWTRVVFSPDGSYVTAGSADGSLYVWSVLTGKVEQVLTKQ 592
           69**********************************99999988888877778************************************ PP
   S: 264  nssvisvavlsfgdnvlvlgsedskvniwk 293
           +ss i   ++s+++ ++v++++ sk+ +w+
   Q: 593  HSSCINAVAWSPSGLHVVSVDKGSKAVLWA 622
           *****************************7 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSSGLRPGDF PRWKRHISEE LRRRDRLQRQ TFEEIILQYN KLLEKSDLHS VLAQKLQAEK 60
HDPPNRHELS PGHDSAWNDS QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGTCGG GTCTCCGCCC CGGCGACTTC CCCCGCTGGA AGCGCCACAT CTCGGAGGAG 60
CTGAGGCGCC GGGACCGGCT GCAGAGGCAG ACGTTCGAGG AGATCATCCT GCAGTGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	29.07	6.00e-33	135.00
IUUC-Aml-002242	Ailuropoda melanoleuca	82.32	0.00e+00	1008.00
IUUC-Apl-003384	Anas platyrhynchos	83.98	0.00e+00	1029.00
IUUC-Aca-004962	Anolis carolinensis	85.07	0.00e+00	1043.00
IUUC-Aly-005435	Arabidopsis lyrata	34.44	8.00e-45	174.00
IUUC-Ath-006948	Arabidopsis thaliana	34.77	1.00e-45	177.00
IUUC-Ame-010915	Astyanax mexicanus	78.15	1.00e-150	525.00
IUUC-Bta-012388	Bos taurus	91.97	0.00e+00	1139.00
IUUC-Bdi-014231	Brachypodium distachyon	28.99	7.00e-37	148.00
IUUC-Bol-016174	Brassica oleracea	35.10	2.00e-45	176.00
IUUC-Bra-017165	Brassica rapa	34.44	1.00e-44	174.00
IUUC-Cel-018131	Caenorhabditis elegans	38.00	2.00e-56	213.00
IUUC-Cja-018898	Callithrix jacchus	82.51	0.00e+00	971.00
IUUC-Cfa-020484	Canis familiaris	90.53	0.00e+00	1119.00
IUUC-Cpo-022156	Cavia porcellus	90.21	0.00e+00	1113.00
IUUC-Csa-024019	Chlorocebus sabaeus	89.09	0.00e+00	1085.00
IUUC-Cho-024311	Choloepus hoffmanni	77.37	0.00e+00	932.00
IUUC-Cin-025260	Ciona intestinalis	37.02	6.00e-98	351.00
IUUC-Csv-025836	Ciona savignyi	43.96	1.00e-46	179.00
IUUC-Dre-027702	Danio rerio	73.69	0.00e+00	879.00
IUUC-Dno-029728	Dasypus novemcinctus	91.33	0.00e+00	1156.00
IUUC-Dor-030587	Dipodomys ordii	82.12	4.00e-123	435.00
IUUC-Dme-031595	Drosophila melanogaster	37.32	2.00e-105	376.00
IUUC-Ete-032969	Echinops telfairi	72.97	0.00e+00	759.00
IUUC-Eca-034214	Equus caballus	91.36	0.00e+00	933.00
IUUC-Eeu-034537	Erinaceus europaeus	84.20	0.00e+00	872.00
IUUC-Fca-036005	Felis catus	92.55	0.00e+00	1076.00
IUUC-Fal-037593	Ficedula albicollis	85.71	0.00e+00	1003.00
IUUC-Gmo-039042	Gadus morhua	62.84	0.00e+00	666.00
IUUC-Gga-040986	Gallus gallus	85.39	0.00e+00	1059.00
IUUC-Gac-041351	Gasterosteus aculeatus	72.06	0.00e+00	890.00
IUUC-Gma-043452	Glycine max	33.77	5.00e-46	178.00
IUUC-Ggo-045427	Gorilla gorilla	94.22	0.00e+00	1144.00
IUUC-Hsa-046632	Homo sapiens	91.33	0.00e+00	1126.00
IUUC-Itr-048504	Ictidomys tridecemlineatus	88.18	0.00e+00	1085.00
IUUC-Lpe-051254	Leersia perrieri	30.07	7.00e-37	148.00
IUUC-Loc-052610	Lepisosteus oculatus	76.17	0.00e+00	925.00
IUUC-Laf-053936	Loxodonta africana	92.12	0.00e+00	1120.00
IUUC-Mcc-055504	Macaca mulatta	91.20	0.00e+00	1156.00
IUUC-Meu-056516	Macropus eugenii	83.47	0.00e+00	999.00
IUUC-Mtr-058062	Medicago truncatula	28.34	2.00e-42	166.00
IUUC-Mga-059777	Meleagris gallopavo	81.07	0.00e+00	1018.00
IUUC-Mmr-061298	Microcebus murinus	95.02	0.00e+00	1153.00
IUUC-Mdo-062969	Monodelphis domestica	88.42	0.00e+00	1082.00
IUUC-Mmu-064076	Mus musculus	93.11	0.00e+00	1132.00
IUUC-Mac-065022	Musa acuminata	32.34	1.00e-40	160.00
IUUC-Mpu-066196	Mustela putorius furo	93.74	0.00e+00	1137.00
IUUC-Mlu-067651	Myotis lucifugus	89.42	0.00e+00	1098.00
IUUC-Nle-069853	Nomascus leucogenys	90.37	0.00e+00	1107.00
IUUC-Opr-070350	Ochotona princeps	75.22	1.00e-131	463.00
IUUC-Ont-072489	Oreochromis niloticus	73.32	0.00e+00	879.00
IUUC-Oan-072703	Ornithorhynchus anatinus	82.48	0.00e+00	972.00
IUUC-Oba-075619	Oryza barthii	30.18	9.00e-36	144.00
IUUC-Obr-076632	Oryza brachyantha	29.12	1.00e-36	147.00
IUUC-Ogl-077671	Oryza glaberrima	30.18	1.00e-35	144.00
IUUC-Ogu-078052	Oryza glumaepatula	30.18	1.00e-35	144.00
IUUC-Oin-079611	Oryza indica	29.82	6.00e-34	138.00
IUUC-Olo-080408	Oryza longistaminata	30.18	2.00e-35	143.00
IUUC-Ome-081560	Oryza meridionalis	30.18	8.00e-36	144.00
IUUC-Oni-082145	Oryza nivara	30.18	9.00e-36	144.00
IUUC-Opu-083918	Oryza punctata	29.82	4.00e-35	142.00
IUUC-Oru-084858	Oryza rufipogon	29.82	9.00e-34	137.00
IUUC-Osa-086277	Oryza sativa	29.82	6.00e-34	138.00
IUUC-Ola-086816	Oryzias latipes	69.12	5.00e-98	350.00
IUUC-Olu-087622	Ostreococcus lucimarinus	33.44	6.00e-44	171.00
IUUC-Oga-088765	Otolemur garnettii	87.18	0.00e+00	1027.00
IUUC-Oar-090196	Ovis aries	89.05	0.00e+00	998.00
IUUC-Ptr-091676	Pan troglodytes	91.49	0.00e+00	1128.00
IUUC-Pan-092068	Papio anubis	94.86	0.00e+00	1147.00
IUUC-Psi-093367	Pelodiscus sinensis	82.83	0.00e+00	1011.00
IUUC-Ppa-095699	Physcomitrella patens	33.33	2.00e-39	156.00
IUUC-Pfo-096067	Poecilia formosa	71.52	0.00e+00	868.00
IUUC-Pab-098111	Pongo abelii	94.54	0.00e+00	1149.00
IUUC-Pop-099116	Populus trichocarpa	31.79	6.00e-42	165.00
IUUC-Pca-100680	Procavia capensis	83.81	0.00e+00	945.00
IUUC-Ppe-101790	Prunus persica	31.46	9.00e-44	171.00
IUUC-Pva-102871	Pteropus vampyrus	91.62	0.00e+00	1058.00
IUUC-Rno-106088	Rattus norvegicus	92.63	0.00e+00	1131.00
IUUC-Sha-106984	Sarcophilus harrisii	86.00	0.00e+00	1043.00
IUUC-Smo-109404	Selaginella moellendorffii	30.99	6.00e-41	161.00
IUUC-Sit-110828	Setaria italica	31.86	1.00e-39	157.00
IUUC-Sly-111009	Solanum lycopersicum	31.35	4.00e-44	172.00
IUUC-Stu-112370	Solanum tuberosum	31.35	7.00e-45	174.00
IUUC-Sar-113659	Sorex araneus	60.38	5.00e-90	323.00
IUUC-Sbi-114819	Sorghum bicolor	30.62	4.00e-38	152.00
IUUC-Ssc-116241	Sus scrofa	88.42	0.00e+00	1079.00
IUUC-Tgu-116576	Taeniopygia guttata	83.79	0.00e+00	1056.00
IUUC-Tru-118336	Takifugu rubripes	64.38	0.00e+00	728.00
IUUC-Tsy-119006	Tarsius syrichta	90.05	0.00e+00	1081.00
IUUC-Tni-120300	Tetraodon nigroviridis	72.55	0.00e+00	857.00
IUUC-Tca-121002	Theobroma cacao	33.03	5.00e-45	175.00
IUUC-Tae-124868	Triticum aestivum	29.76	9.00e-34	137.00
IUUC-Tur-126463	Triticum urartu	29.07	2.00e-33	137.00
IUUC-Tbe-127631	Tupaia belangeri	91.08	0.00e+00	903.00
IUUC-Ttr-129005	Tursiops truncatus	82.30	2.00e-159	556.00
IUUC-Vpa-130246	Vicugna pacos	84.90	0.00e+00	850.00
IUUC-Vvi-130878	Vitis vinifera	33.76	4.00e-43	169.00
IUUC-Xtr-132798	Xenopus tropicalis	72.29	0.00e+00	851.00
IUUC-Xma-133264	Xiphophorus maculatus	71.03	0.00e+00	863.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence