iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074370

UUCD1 version

UUC-OrC-00089

Ensembl Protein ID

ENSOCUP00000002075.3

UniProt Accession

G1SHH0; G1SHH0_RABIT

Protein Name

Uncharacterized protein

Gene Name

UBE4A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000002397.3	ENSOCUT00000002400.3	ENSOCUP00000002075.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.90e-22	79.2	870	941

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
            ++efl+pI+ +lM+dPvvlp s++t+drs+I+++l s+++ +P++r+plt +++ Pn++l++ iq+w++e++
   Q: 870  ACDEFLDPIMSTLMSDPVVLPsSRVTVDRSTIARHLLSDQT-DPFNRSPLTMDQIRPNTELKEKIQRWLAERK 941
           579******************9******************9.***************************9976 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAVELEDQDW LDMSNVEQAI FARLLLQDPG NHLINMTSST TLNLSADRDA GERHIFCYLY 60
SCFQRAKEEI TKVPENLLPF AVQCRNLTVS NTRTILLTPE IYVDQNIHEQ LVELMLEAIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCTCCCCC TAGGTCTGGA TGGAGGATAA CTTAAAGTGA AATGACAGAC CAGGAGAATA 60
ACAACAACAT CTCAAGTAAC CCCTTTGCTG CTCTTTTTGG CTCCCTGGCT GATGCCAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001281	Ailuropoda melanoleuca	97.07	0.00e+00	1841.00
IUUC-Apl-003514	Anas platyrhynchos	89.29	0.00e+00	1746.00
IUUC-Aca-005167	Anolis carolinensis	85.85	0.00e+00	1590.00
IUUC-Ame-010905	Astyanax mexicanus	66.81	5.00e-163	568.00
IUUC-Bta-012413	Bos taurus	95.57	0.00e+00	1840.00
IUUC-Cja-019715	Callithrix jacchus	96.76	0.00e+00	1860.00
IUUC-Cfa-021185	Canis familiaris	97.47	0.00e+00	1897.00
IUUC-Cpo-021516	Cavia porcellus	97.68	0.00e+00	1863.00
IUUC-Csa-023765	Chlorocebus sabaeus	97.89	0.00e+00	1844.00
IUUC-Cho-024614	Choloepus hoffmanni	98.41	0.00e+00	865.00
IUUC-Cin-025532	Ciona intestinalis	36.81	1.00e-163	570.00
IUUC-Csv-025834	Ciona savignyi	52.90	7.00e-49	185.00
IUUC-Dre-028223	Danio rerio	77.37	0.00e+00	1464.00
IUUC-Dno-029785	Dasypus novemcinctus	96.63	0.00e+00	1854.00
IUUC-Dor-030421	Dipodomys ordii	92.57	0.00e+00	1734.00
IUUC-Dme-031715	Drosophila melanogaster	36.00	7.00e-134	471.00
IUUC-Ete-032767	Echinops telfairi	93.84	0.00e+00	1306.00
IUUC-Eca-033587	Equus caballus	97.05	0.00e+00	1863.00
IUUC-Fca-035622	Felis catus	96.55	0.00e+00	1890.00
IUUC-Fal-037262	Ficedula albicollis	88.18	0.00e+00	1701.00
IUUC-Gmo-038686	Gadus morhua	73.66	0.00e+00	1446.00
IUUC-Gga-041222	Gallus gallus	88.34	0.00e+00	1729.00
IUUC-Gac-042637	Gasterosteus aculeatus	73.87	0.00e+00	1435.00
IUUC-Gma-043587	Glycine max	29.23	3.00e-91	330.00
IUUC-Ggo-044685	Gorilla gorilla	96.97	0.00e+00	1863.00
IUUC-Hsa-046176	Homo sapiens	97.58	0.00e+00	1870.00
IUUC-Itr-048469	Ictidomys tridecemlineatus	98.14	0.00e+00	1065.00
IUUC-Lch-049630	Latimeria chalumnae	81.42	0.00e+00	1582.00
IUUC-Loc-052727	Lepisosteus oculatus	78.06	0.00e+00	1506.00
IUUC-Laf-054041	Loxodonta africana	96.10	0.00e+00	1874.00
IUUC-Mcc-055099	Macaca mulatta	97.68	0.00e+00	1870.00
IUUC-Meu-055991	Macropus eugenii	88.94	0.00e+00	1740.00
IUUC-Mga-059596	Meleagris gallopavo	88.88	0.00e+00	1729.00
IUUC-Mmr-061244	Microcebus murinus	95.48	0.00e+00	1494.00
IUUC-Mdo-062335	Monodelphis domestica	90.54	0.00e+00	1740.00
IUUC-Mmu-063572	Mus musculus	96.31	0.00e+00	1843.00
IUUC-Mpu-066444	Mustela putorius furo	92.54	0.00e+00	1785.00
IUUC-Mlu-068232	Myotis lucifugus	95.36	0.00e+00	1834.00
IUUC-Nle-070036	Nomascus leucogenys	96.86	0.00e+00	1859.00
IUUC-Opr-070503	Ochotona princeps	96.82	0.00e+00	1209.00
IUUC-Ont-072389	Oreochromis niloticus	76.68	0.00e+00	1472.00
IUUC-Oan-073114	Ornithorhynchus anatinus	87.96	0.00e+00	1670.00
IUUC-Ola-086562	Oryzias latipes	74.29	0.00e+00	1453.00
IUUC-Oga-088146	Otolemur garnettii	95.45	0.00e+00	1826.00
IUUC-Oar-089190	Ovis aries	95.36	0.00e+00	1804.00
IUUC-Ptr-090592	Pan troglodytes	96.76	0.00e+00	1859.00
IUUC-Pan-092271	Papio anubis	97.68	0.00e+00	1872.00
IUUC-Psi-093730	Pelodiscus sinensis	87.71	0.00e+00	1697.00
IUUC-Pma-094120	Petromyzon marinus	77.38	3.00e-133	467.00
IUUC-Pfo-097077	Poecilia formosa	73.71	0.00e+00	1417.00
IUUC-Pab-098069	Pongo abelii	96.76	0.00e+00	1824.00
IUUC-Pca-100762	Procavia capensis	92.99	0.00e+00	1758.00
IUUC-Pva-103149	Pteropus vampyrus	95.82	0.00e+00	1845.00
IUUC-Rno-105342	Rattus norvegicus	96.21	0.00e+00	1841.00
IUUC-Sha-106555	Sarcophilus harrisii	90.33	0.00e+00	1768.00
IUUC-Sly-110848	Solanum lycopersicum	39.41	3.00e-76	279.00
IUUC-Sar-113131	Sorex araneus	89.57	0.00e+00	1176.00
IUUC-Ssc-115841	Sus scrofa	96.52	0.00e+00	1855.00
IUUC-Tgu-116823	Taeniopygia guttata	87.74	0.00e+00	1700.00
IUUC-Tru-118249	Takifugu rubripes	75.21	0.00e+00	1429.00
IUUC-Tsy-119112	Tarsius syrichta	97.35	0.00e+00	740.00
IUUC-Tni-119848	Tetraodon nigroviridis	75.00	0.00e+00	1428.00
IUUC-Tbe-127889	Tupaia belangeri	81.51	0.00e+00	673.00
IUUC-Ttr-129300	Tursiops truncatus	84.59	0.00e+00	925.00
IUUC-Vpa-130215	Vicugna pacos	95.50	0.00e+00	1858.00
IUUC-Xtr-132107	Xenopus tropicalis	80.17	0.00e+00	1543.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence