iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052186

Ensembl Protein ID

ENSLOCP00000004730.1

UniProt Accession

W5M8M2; W5M8M2_LEPOC

Genbank Protein ID

ENSLOCP00000004730

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01029696

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000003963.1	ENSLOCT00000004738.1	ENSLOCP00000004730.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	4.90e-230	765.5	36	664

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeqlLktynreWekfreqlkvlrkifay 89
           l++a+++i+r++++  ++eely+++y+++l+k+g+klY+ l+ev++e++ ++v+++v +s ++++L+t+n++W++++++++++r+i++y
   Q: 36   LKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLiNKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMY 124
           799*********************************************99*************************************** PP
   S: 90   ldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleat 176
           +dr+yv++ ++v++v++L+l ++r+++v++  i+++l ++ll++i++eRkge+vdr  +++++++l+ L+l+ +++y+e+FEa+fle++
   Q: 125  MDRVYVQQ-NNVENVYNLGLIIFRDQVVRYgcIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMS 212
           ********.******************************************************************************** PP
   S: 177  qefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll....aelvallrdkktedlsrmykL 261
           +ef+++es++fl+en+ + Y+kkvear+nee er++++l++ste+++++vve+eli+kh+++++    ++lv++l++ ktedl++mykL
   Q: 213  AEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVemenSGLVHMLKNGKTEDLACMYKL 301
           ****************************************************************99999******************** PP
   S: 262  lsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaakspE 350
           +srv+ngl++++++++s+++eqgka++++e + k+p++y++ ll+lk++++++++e+Fnnd+ F ++++ +fe+f+n n     ++spE
   Q: 302  FSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLN-----SRSPE 385
           *******************************************************************************.....***** PP
   S: 351  llAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfq 439
           +l+ +iD++L+k++kglte+e+e++ldk++++f++++ekdvFe+yYk+hLa+RLl++ks+s+++E+++i+kLk+ecg++ftskLe+Mf+
   Q: 386  YLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFR 474
           ***************************************************************************************** PP
   S: 440  dlkvSedlnrqFkeekentees.esvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkael. 526
           d+++S++++++F+++ ++t  s  +v+l+v+vL++g+Wpt+s+t+k+++P+  ++++e f++fYl khsgR+L++qh++g+a+l+a++ 
   Q: 475  DMSISNTTMDEFRQHLQSTGVSlGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEVFRRFYLAKHSGRQLTLQHHMGSADLNATFy 563
           ********************99889**************************************************************** PP
   S: 527  .....................kkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqvlkkepeskei 592
                                +++k++lqVstfQm++L++fnn+ek+++ee++++t++pe+eL r+lqsL+++k  ++vl+kep+skei
   Q: 564  gpikkedgsevgvggaqvtgsNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKptQRVLTKEPKSKEI 652
           *********999999998888888***************************************************************** PP
   S: 593  eeedlfsvNqef 604
           e++++f+vN++f
   Q: 653  ENGHVFTVNDQF 664
           **********99 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSNLSKGGTK KDTKMRIRAF PMTMDEKYVN NIWDLLKNAI QEIQRKNNSG LSFEELYRNA 60
YTMVLHKHGE KLYTGLREVV TEHLINKVRE DVLNSLNNNF LQTLNQAWND HQTAMVMIRD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGAGCCGA GCACTTGGAG TGGCGGCGGC GGCGGAGTGA CAATACCAGC CCAGAAAGAG 60
GGACGTAGAC ACGCCGGAGA GGTCGAGGGG GCTAAACGGC ATTCCCGTCG GCACATTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000335	Aegilops tauschii	47.07	0.00e+00	686.00
IUUC-Aml-002278	Ailuropoda melanoleuca	97.93	0.00e+00	1543.00
IUUC-Atr-002616	Amborella trichopoda	52.88	0.00e+00	775.00
IUUC-Apl-004172	Anas platyrhynchos	99.20	0.00e+00	1516.00
IUUC-Aca-004309	Anolis carolinensis	98.83	0.00e+00	1555.00
IUUC-Aly-005566	Arabidopsis lyrata	51.77	0.00e+00	768.00
IUUC-Ath-007587	Arabidopsis thaliana	52.17	0.00e+00	773.00
IUUC-Ago-007795	Ashbya gossypii	25.64	6.00e-49	189.00
IUUC-Acl-008317	Aspergillus clavatus	36.48	4.00e-145	508.00
IUUC-Afl-008727	Aspergillus flavus	36.53	9.00e-145	507.00
IUUC-Afu-008879	Aspergillus fumigatus	37.96	5.00e-133	468.00
IUUC-Ani-009393	Aspergillus nidulans	35.79	4.00e-136	478.00
IUUC-Ang-009626	Aspergillus niger	36.69	7.00e-142	498.00
IUUC-Aor-010207	Aspergillus oryzae	36.53	1.00e-144	507.00
IUUC-Ate-010305	Aspergillus terreus	37.18	2.00e-140	493.00
IUUC-Ame-011805	Astyanax mexicanus	97.91	0.00e+00	1529.00
IUUC-Bgr-012098	Blumeria graminis	36.40	2.00e-121	430.00
IUUC-Bta-013445	Bos taurus	98.83	0.00e+00	1554.00
IUUC-Bci-013612	Botrytis cinerea	36.85	8.00e-140	491.00
IUUC-Bdi-014269	Brachypodium distachyon	52.54	0.00e+00	752.00
IUUC-Bol-015350	Brassica oleracea	52.30	0.00e+00	771.00
IUUC-Bra-016763	Brassica rapa	52.43	0.00e+00	774.00
IUUC-Cel-018641	Caenorhabditis elegans	48.59	0.00e+00	731.00
IUUC-Cja-019175	Callithrix jacchus	98.70	0.00e+00	1551.00
IUUC-Cfa-020905	Canis familiaris	98.80	0.00e+00	1519.00
IUUC-Cpo-021293	Cavia porcellus	97.76	0.00e+00	1522.00
IUUC-Cre-022776	Chlamydomonas reinhardtii	48.43	0.00e+00	701.00
IUUC-Csa-023800	Chlorocebus sabaeus	98.57	0.00e+00	1550.00
IUUC-Cho-024839	Choloepus hoffmanni	98.24	0.00e+00	1352.00
IUUC-Cin-025201	Ciona intestinalis	72.43	0.00e+00	1035.00
IUUC-Csv-026107	Ciona savignyi	71.64	0.00e+00	1098.00
IUUC-Cgl-026630	Colletotrichum gloeosporioides	35.31	2.00e-124	440.00
IUUC-Cne-027048	Cryptococcus neoformans	34.80	1.00e-117	417.00
IUUC-Cme-027254	Cyanidioschyzon merolae	30.73	1.00e-88	320.00
IUUC-Dre-028488	Danio rerio	98.70	0.00e+00	1544.00
IUUC-Dno-029784	Dasypus novemcinctus	98.70	0.00e+00	1551.00
IUUC-Dor-030682	Dipodomys ordii	91.82	0.00e+00	1363.00
IUUC-Dse-031326	Dothistroma septosporum	35.83	3.00e-128	452.00
IUUC-Dme-032112	Drosophila melanogaster	69.30	0.00e+00	1080.00
IUUC-Ete-032347	Echinops telfairi	82.04	0.00e+00	1189.00
IUUC-Eca-033560	Equus caballus	99.33	0.00e+00	1516.00
IUUC-Eeu-034502	Erinaceus europaeus	97.21	0.00e+00	1342.00
IUUC-Fca-035544	Felis catus	99.20	0.00e+00	1516.00
IUUC-Fal-036751	Ficedula albicollis	99.20	0.00e+00	1518.00
IUUC-Fox-037857	Fusarium oxysporum	37.01	1.00e-137	483.00
IUUC-Fso-038163	Fusarium solani	36.82	1.00e-141	496.00
IUUC-Gmo-039270	Gadus morhua	97.67	0.00e+00	1540.00
IUUC-Ggr-039999	Gaeumannomyces graminis	34.00	2.00e-128	453.00
IUUC-Gga-040329	Gallus gallus	98.96	0.00e+00	1555.00
IUUC-Gac-041510	Gasterosteus aculeatus	97.80	0.00e+00	1536.00
IUUC-Gma-043659	Glycine max	52.48	0.00e+00	748.00
IUUC-Ggo-044903	Gorilla gorilla	98.80	0.00e+00	1507.00
IUUC-Hsa-046000	Homo sapiens	98.57	0.00e+00	1550.00
IUUC-Hvu-047831	Hordeum vulgare	52.46	0.00e+00	701.00
IUUC-Itr-049067	Ictidomys tridecemlineatus	98.89	0.00e+00	937.00
IUUC-Kpa-049372	Komagataella pastoris	34.94	2.00e-115	410.00
IUUC-Lch-050458	Latimeria chalumnae	97.77	0.00e+00	1518.00
IUUC-Lpe-051396	Leersia perrieri	51.76	0.00e+00	761.00
IUUC-Lma-053030	Leptosphaeria maculans	38.42	4.00e-144	505.00
IUUC-Laf-053684	Loxodonta africana	99.20	0.00e+00	1516.00
IUUC-Mcc-055770	Macaca mulatta	98.57	0.00e+00	1550.00
IUUC-Meu-056852	Macropus eugenii	98.63	0.00e+00	759.00
IUUC-Mor-057273	Magnaporthe oryzae	34.76	2.00e-133	469.00
IUUC-Mpo-057403	Magnaporthe poae	34.24	6.00e-130	458.00
IUUC-Mtr-058317	Medicago truncatula	51.86	0.00e+00	752.00
IUUC-Mla-059055	Melampsora laricipopulina	37.31	2.00e-133	470.00
IUUC-Mga-060076	Meleagris gallopavo	97.72	0.00e+00	1488.00
IUUC-Mvi-060470	Microbotryum violaceum	33.52	2.00e-135	476.00
IUUC-Mmr-060976	Microcebus murinus	98.83	0.00e+00	1554.00
IUUC-Mdo-062741	Monodelphis domestica	98.83	0.00e+00	1554.00
IUUC-Mmu-063905	Mus musculus	98.57	0.00e+00	1550.00
IUUC-Mac-064718	Musa acuminata	50.85	0.00e+00	732.00
IUUC-Mpu-066356	Mustela putorius furo	99.20	0.00e+00	1516.00
IUUC-Mlu-067768	Myotis lucifugus	98.67	0.00e+00	1511.00
IUUC-Nfi-068285	Neosartorya fischeri	37.20	3.00e-146	512.00
IUUC-Ncr-068883	Neurospora crassa	36.68	1.00e-138	487.00
IUUC-Nle-069638	Nomascus leucogenys	98.93	0.00e+00	1511.00
IUUC-Opr-070333	Ochotona princeps	90.18	0.00e+00	1267.00
IUUC-Ont-071601	Oreochromis niloticus	99.09	0.00e+00	1587.00
IUUC-Oan-073281	Ornithorhynchus anatinus	99.36	0.00e+00	1301.00
IUUC-Ocu-074504	Oryctolagus cuniculus	99.06	0.00e+00	1519.00
IUUC-Oba-075332	Oryza barthii	52.30	0.00e+00	753.00
IUUC-Obr-076435	Oryza brachyantha	53.12	0.00e+00	716.00
IUUC-Ogl-077655	Oryza glaberrima	52.28	0.00e+00	764.00
IUUC-Ogu-078458	Oryza glumaepatula	52.30	0.00e+00	754.00
IUUC-Oin-079567	Oryza indica	52.15	0.00e+00	761.00
IUUC-Olo-080930	Oryza longistaminata	53.02	0.00e+00	758.00
IUUC-Ome-081353	Oryza meridionalis	52.28	0.00e+00	762.00
IUUC-Oni-082378	Oryza nivara	52.28	0.00e+00	764.00
IUUC-Opu-084055	Oryza punctata	52.15	0.00e+00	763.00
IUUC-Oru-084202	Oryza rufipogon	52.30	0.00e+00	754.00
IUUC-Osa-085290	Oryza sativa	52.28	0.00e+00	764.00
IUUC-Ola-087562	Oryzias latipes	98.83	0.00e+00	1551.00
IUUC-Olu-087866	Ostreococcus lucimarinus	38.21	1.00e-140	493.00
IUUC-Oga-088833	Otolemur garnettii	99.20	0.00e+00	1516.00
IUUC-Oar-089958	Ovis aries	99.20	0.00e+00	1516.00
IUUC-Ptr-091013	Pan troglodytes	98.57	0.00e+00	1550.00
IUUC-Pan-091796	Papio anubis	98.27	0.00e+00	1503.00
IUUC-Psi-093564	Pelodiscus sinensis	97.72	0.00e+00	1482.00
IUUC-Pno-094939	Phaeosphaeria nodorum	38.10	2.00e-138	486.00
IUUC-Ppa-095920	Physcomitrella patens	51.97	0.00e+00	766.00
IUUC-Pfo-097498	Poecilia formosa	94.63	0.00e+00	1532.00
IUUC-Pab-098164	Pongo abelii	98.57	0.00e+00	1550.00
IUUC-Pop-099497	Populus trichocarpa	53.21	0.00e+00	788.00
IUUC-Pca-100702	Procavia capensis	90.89	0.00e+00	1381.00
IUUC-Ppe-101271	Prunus persica	52.10	0.00e+00	744.00
IUUC-Pva-103129	Pteropus vampyrus	98.96	0.00e+00	1555.00
IUUC-Pgr-103684	Puccinia graminis	36.57	9.00e-111	394.00
IUUC-Ptt-103961	Puccinia triticina	36.75	9.00e-110	391.00
IUUC-Pte-104325	Pyrenophora teres	38.06	2.00e-136	479.00
IUUC-Pyt-104746	Pyrenophora triticirepentis	37.09	3.00e-134	472.00
IUUC-Rno-105935	Rattus norvegicus	99.06	0.00e+00	1515.00
IUUC-Sce-106354	Saccharomyces cerevisiae	27.01	3.00e-53	203.00
IUUC-Sha-106569	Sarcophilus harrisii	98.83	0.00e+00	1383.00
IUUC-Sja-107676	Schizosaccharomyces japonicus	38.63	1.00e-154	540.00
IUUC-Spo-108135	Schizosaccharomyces pombe	37.64	2.00e-138	486.00
IUUC-Smo-109555	Selaginella moellendorffii	53.62	0.00e+00	790.00
IUUC-Sit-110763	Setaria italica	52.93	0.00e+00	768.00
IUUC-Sly-111090	Solanum lycopersicum	51.84	0.00e+00	764.00
IUUC-Stu-112351	Solanum tuberosum	51.97	0.00e+00	766.00
IUUC-Sar-113144	Sorex araneus	99.27	0.00e+00	1115.00
IUUC-Sbi-114690	Sorghum bicolor	52.15	0.00e+00	768.00
IUUC-Sre-115005	Sporisorium reilianum	38.04	2.00e-135	476.00
IUUC-Ssc-116053	Sus scrofa	98.91	0.00e+00	1139.00
IUUC-Tgu-116523	Taeniopygia guttata	99.20	0.00e+00	1516.00
IUUC-Tru-118189	Takifugu rubripes	94.78	0.00e+00	1455.00
IUUC-Tsy-118962	Tarsius syrichta	93.00	0.00e+00	1386.00
IUUC-Tni-120614	Tetraodon nigroviridis	57.22	0.00e+00	880.00
IUUC-Tca-121282	Theobroma cacao	52.62	0.00e+00	769.00
IUUC-Tre-122201	Trichoderma reesei	36.01	3.00e-134	472.00
IUUC-Tvi-122321	Trichoderma virens	36.50	1.00e-134	474.00
IUUC-Tae-124292	Triticum aestivum	51.89	0.00e+00	747.00
IUUC-Tur-126800	Triticum urartu	51.63	0.00e+00	744.00
IUUC-Tme-127053	Tuber melanosporum	40.61	1.00e-156	546.00
IUUC-Tbe-127427	Tupaia belangeri	84.64	0.00e+00	1162.00
IUUC-Ttr-128662	Tursiops truncatus	97.32	0.00e+00	1476.00
IUUC-Uma-129597	Ustilago maydis	38.40	1.00e-134	473.00
IUUC-Vda-129726	Verticillium dahliae	35.60	3.00e-134	472.00
IUUC-Vpa-130809	Vicugna pacos	99.73	0.00e+00	744.00
IUUC-Vvi-131194	Vitis vinifera	53.00	0.00e+00	763.00
IUUC-Xtr-131887	Xenopus tropicalis	97.79	0.00e+00	1536.00
IUUC-Xma-133517	Xiphophorus maculatus	98.96	0.00e+00	1554.00
IUUC-Yli-134576	Yarrowia lipolytica	33.59	2.00e-111	397.00
IUUC-Zma-135030	Zea mays	52.54	0.00e+00	776.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence