iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000004629.1	ENSAMET00000005087.1	ENSAMEP00000004890.1
ENSAMEG00000004629.1	ENSAMET00000005094.1	ENSAMEP00000004897.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.00e-05	25.6	14	70
E3 activity/RING/RING	2.50e-06	28.0	16	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltl 61
           +lCp+ +++Mr+Pv ++ +G+ +  ++++++l++g  +cP ++ pl+  ++ P  +l
   Q: 14   LLCPLCGKPMREPVQVStCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPEL 70
           79*************999*****************99*********99999998776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  ++++++ v  CgH f+ +Clq +     +s + f+CP 
   Q: 16   CPLCGKPMREPVQVSTCGHRFCDTCLQEF-----LSEGVFKCPE 54
           ********99888888**********999.....89*******6 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

PGFDYKXXXX XRRLLCPLCG KPMREPVQVS TCGHRFCDTC LQEFLSEGVF KCPEDQLPLD 60
YAKIYPDPEL EVQVLGLAIR CIHSEEGCRW SGPLRHLQSH LNTCSFNVIP CPNRCSTKLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCGGCT TCGACTACAA GTNNNNNNNN NNNNNNCGGC GGCTGCTGTG CCCGCTGTGC 60
GGAAAGCCCA TGCGCGAGCC GGTGCAGGTT TCTACCTGCG GCCACCGCTT CTGCGACACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000797	Aegilops tauschii	42.25	1.00e-08	54.30
IUUC-Ame-011530	Astyanax mexicanus	76.55	0.00e+00	755.00
IUUC-Bta-013582	Bos taurus	96.80	0.00e+00	900.00
IUUC-Bdi-014617	Brachypodium distachyon	25.41	6.00e-06	47.00
IUUC-Cja-019883	Callithrix jacchus	93.75	2.00e-51	194.00
IUUC-Cfa-020133	Canis familiaris	91.90	0.00e+00	837.00
IUUC-Cpo-022021	Cavia porcellus	96.38	0.00e+00	899.00
IUUC-Csa-023199	Chlorocebus sabaeus	96.38	0.00e+00	899.00
IUUC-Dre-028193	Danio rerio	75.91	0.00e+00	753.00
IUUC-Dno-028917	Dasypus novemcinctus	97.23	0.00e+00	906.00
IUUC-Ete-032433	Echinops telfairi	95.52	0.00e+00	890.00
IUUC-Fca-036155	Felis catus	98.08	0.00e+00	910.00
IUUC-Gmo-038860	Gadus morhua	75.69	0.00e+00	748.00
IUUC-Gga-041052	Gallus gallus	82.09	0.00e+00	825.00
IUUC-Gac-041489	Gasterosteus aculeatus	75.91	0.00e+00	747.00
IUUC-Ggo-044996	Gorilla gorilla	96.16	0.00e+00	894.00
IUUC-Hsa-046252	Homo sapiens	96.38	0.00e+00	897.00
IUUC-Hvu-047127	Hordeum vulgare	38.03	1.00e-07	50.80
IUUC-Itr-048232	Ictidomys tridecemlineatus	96.59	0.00e+00	900.00
IUUC-Kpa-049340	Komagataella pastoris	27.06	4.00e-16	79.30
IUUC-Lpe-051100	Leersia perrieri	40.32	6.00e-08	51.60
IUUC-Loc-052312	Lepisosteus oculatus	76.38	0.00e+00	754.00
IUUC-Laf-054376	Loxodonta africana	97.23	0.00e+00	905.00
IUUC-Mcc-055684	Macaca mulatta	96.38	0.00e+00	899.00
IUUC-Mmr-061198	Microcebus murinus	96.59	0.00e+00	899.00
IUUC-Mdo-062585	Monodelphis domestica	86.35	0.00e+00	816.00
IUUC-Mmu-064303	Mus musculus	95.52	0.00e+00	894.00
IUUC-Mac-064529	Musa acuminata	30.40	2.00e-10	60.10
IUUC-Mpu-066854	Mustela putorius furo	97.65	0.00e+00	907.00
IUUC-Nle-070098	Nomascus leucogenys	95.10	0.00e+00	885.00
IUUC-Ont-071518	Oreochromis niloticus	76.07	0.00e+00	749.00
IUUC-Ocu-073841	Oryctolagus cuniculus	96.38	0.00e+00	898.00
IUUC-Obr-076500	Oryza brachyantha	40.85	2.00e-08	53.50
IUUC-Ogu-078582	Oryza glumaepatula	38.71	3.00e-07	49.30
IUUC-Oin-079499	Oryza indica	38.71	3.00e-07	49.30
IUUC-Ome-081269	Oryza meridionalis	40.32	6.00e-08	51.20
IUUC-Opu-083468	Oryza punctata	40.32	5.00e-08	51.60
IUUC-Osa-085740	Oryza sativa	38.71	4.00e-07	48.50
IUUC-Ola-086674	Oryzias latipes	76.28	0.00e+00	749.00
IUUC-Oga-088510	Otolemur garnettii	96.38	0.00e+00	898.00
IUUC-Oar-089225	Ovis aries	92.96	0.00e+00	855.00
IUUC-Pan-092725	Papio anubis	96.38	0.00e+00	899.00
IUUC-Pfo-096341	Poecilia formosa	75.85	0.00e+00	750.00
IUUC-Ppe-101708	Prunus persica	30.16	2.00e-07	52.00
IUUC-Pva-103131	Pteropus vampyrus	99.24	1.00e-143	503.00
IUUC-Rno-105996	Rattus norvegicus	95.74	0.00e+00	894.00
IUUC-Sly-111800	Solanum lycopersicum	30.83	1.00e-06	49.30
IUUC-Sbi-113900	Sorghum bicolor	38.03	2.00e-07	49.70
IUUC-Tru-117602	Takifugu rubripes	76.55	0.00e+00	757.00
IUUC-Tur-126067	Triticum urartu	42.25	7.00e-09	54.70
IUUC-Ttr-128370	Tursiops truncatus	96.25	0.00e+00	701.00
IUUC-Vvi-131592	Vitis vinifera	31.19	6.00e-07	50.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence