iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042500

UUCD1 version

UUC-GaA-00220

Ensembl Protein ID

ENSGACP00000006023.1

UniProt Accession

G3NL10; G3NL10_GASAC

Protein Name

Uncharacterized protein

Gene Name

atg16l2; ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000004539.1	ENSGACT00000006026.1	ENSGACP00000006009.1
ENSGACG00000004539.1	ENSGACT00000006040.1	ENSGACP00000006023.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.60e-32	108.1	324	361
UBD/Beta-Prp	5.40e-46	157.5	322	610

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           H+ ++++++f s+ +ll++G+ D  +kvW++r+g l++
   Q: 324  HEQGINAVRFsSSsHLLATGGTDREVKVWEVRSGSLTH 361
           999*******95559******************99875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h++ i++v fs ++ llatg++d+ +kvw+v++g+l    +l g ++++t+++f+p g  ++ +s D+ + +w l+++    tl+gh
   Q: 322  EAHEQGINAVRFSSSSHLLATGGTDREVKVWEVRSGSLthRTTLDGSTGGITCIEFDPMGFRILAASYDKSALLWRLDDSVAKLTLTGH 410
           6888899*******************************54456799**************9**************************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlk.tgkllrtltgghtd 181
            ++v++ +fs   + +v+Gs+dr ir+wdl+   c+e +l++ +   +c  + +++n ++sG+ D+ +r+Wd +   +++++l    ++
   Q: 411  RRKVTAARFSGCLHQVVTGSEDRSIRLWDLQRAACVE-VLEVSS---SCSDLVCSENSVISGHFDSRIRVWDTRwLLRCVQELPA--QG 493
           ************************************9.999998...7888888889****************63689*****65..99 PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlq...tgec...vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           +v+sl+++s+ ++l+s+ +d  ++l+dl+   ++++    + +++ +d       sp++ +l+ gs+Dg ++iW++ +g+l + l  ++
   Q: 494  KVTSLDISSDHRHLLSCCRDDCLQLVDLRgrsNERVcfrAEGFKCGSDSS-KAVISPDGCFLAAGSADGAVYIWNVSTGNLETRLPDRH 581
           *****************************887555533333444444444.456679******************************** PP
   S: 265  ssvisvavlsfgdnvlvlgsedskvniwk 293
           ss+is  ++s+++ ++v++++  ++ +w+
   Q: 582  SSSISAVAWSLSGEYVVSVDKSRRAVLWS 610
           999999999***********999999985 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

LPGPRAVMAD SPREAWKRHI VGQLKHRDRS QHDRYQDLIP LLKFLSHLFW SVYSVDKNSK 60
EVVRKLNCST SSASDSRPAD VSSDGRSVPS LRQQNEQLRK TSGELAYQVL ELQQQTRTRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCTGCCCG GGCCGCGCGC AGTCATGGCG GATTCACCCC GAGTCCCGCG GCACGGCGGC 60
CGGGACGCGG CGCCCGCGCT GCCCCGGGCC CGGTCGACGG AGGCCTGGAA GAGACACATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011152	Astyanax mexicanus	50.34	4.00e-145	508.00
IUUC-Bta-013118	Bos taurus	41.15	1.00e-98	353.00
IUUC-Cja-020002	Callithrix jacchus	40.58	3.00e-99	355.00
IUUC-Csa-024134	Chlorocebus sabaeus	40.35	1.00e-95	343.00
IUUC-Cho-024853	Choloepus hoffmanni	36.50	1.00e-76	280.00
IUUC-Dre-027949	Danio rerio	53.41	3.00e-168	585.00
IUUC-Dno-029683	Dasypus novemcinctus	43.07	5.00e-102	364.00
IUUC-Eca-033303	Equus caballus	50.31	2.00e-80	292.00
IUUC-Eeu-035336	Erinaceus europaeus	52.43	3.00e-75	276.00
IUUC-Gmo-038880	Gadus morhua	74.23	1.00e-104	373.00
IUUC-Ggo-045130	Gorilla gorilla	48.56	2.00e-86	313.00
IUUC-Hsa-046359	Homo sapiens	40.82	4.00e-97	348.00
IUUC-Lch-050669	Latimeria chalumnae	51.06	6.00e-86	310.00
IUUC-Loc-052789	Lepisosteus oculatus	49.84	4.00e-139	488.00
IUUC-Mdo-061841	Monodelphis domestica	40.00	5.00e-104	371.00
IUUC-Mmu-064065	Mus musculus	39.90	4.00e-100	358.00
IUUC-Mpu-066742	Mustela putorius furo	48.85	1.00e-91	330.00
IUUC-Mlu-067019	Myotis lucifugus	49.85	2.00e-80	293.00
IUUC-Nle-069037	Nomascus leucogenys	40.82	3.00e-103	369.00
IUUC-Opr-071039	Ochotona princeps	41.21	2.00e-101	363.00
IUUC-Oan-073431	Ornithorhynchus anatinus	45.48	6.00e-85	307.00
IUUC-Ocu-074772	Oryctolagus cuniculus	43.75	3.00e-89	322.00
IUUC-Ola-086964	Oryzias latipes	75.60	7.00e-126	442.00
IUUC-Oga-088188	Otolemur garnettii	40.81	4.00e-95	342.00
IUUC-Psi-093652	Pelodiscus sinensis	41.80	9.00e-94	337.00
IUUC-Pfo-096960	Poecilia formosa	58.76	5.00e-165	574.00
IUUC-Pab-097776	Pongo abelii	48.28	3.00e-85	309.00
IUUC-Pva-103135	Pteropus vampyrus	39.35	1.00e-87	317.00
IUUC-Rno-105529	Rattus norvegicus	40.03	4.00e-107	382.00
IUUC-Sha-107062	Sarcophilus harrisii	39.52	3.00e-105	375.00
IUUC-Sar-113109	Sorex araneus	52.19	2.00e-55	210.00
IUUC-Tni-120373	Tetraodon nigroviridis	65.64	2.00e-113	402.00
IUUC-Ttr-128267	Tursiops truncatus	47.41	2.00e-84	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence