iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088188

Ensembl Protein ID

ENSOGAP00000011189.2

UniProt Accession

H0X723; H0X723_OTOGA

Genbank Protein ID

ENSOGAP00000011189

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03001258

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000012494.2	ENSOGAT00000012499.2	ENSOGAP00000011189.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-26	90.8	334	368
UBD/Beta-Prp	3.10e-44	151.3	332	617

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H ++v++++f ++  ll++G+ D+ i++W++  g+
   Q: 334  HLSEVNAVCFgPSgSLLATGGADCLIHLWNVVGGR 368
           99*********6669***************97666 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++sllatg++d  i +w+v  g l   ++l+g  + +t+v+f+p+g+  + +   r++++w +   +   tl+gh
   Q: 332  DAHLSEVNAVCFGPSGSLLATGGADCLIHLWNVVGGRLkaNQTLEGAGGSITSVDFDPSGSQVLAATYNRAAHLWKVGEIQSKETLSGH 420
           689999******************************9988899******************999************************* PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  ++++ v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++   +++      +++
   Q: 421  KDKVTAAKFKLTRHHAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPHCIQVIP--VQGR 503
           ************************************9.666655...4555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d t+k+ dl+ +++ + +++       d++k   fsp+  + + gs Dg ++iWd+++g+l ++l +++  
   Q: 504  VTSLSLSHDQLHLLSCSRDDTLKVIDLRVSNIRQVFRADGfrcgsDWTK-AVFSPDRSYALAGSWDGALYIWDVDTGKLESSLWGPHCA 591
           ****************************888855555544445526666.8899*********************************77 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            i   +++ +++ +v++++  kv +w
   Q: 592  AINAVAWCCSGSCVVSVDQGRKVVLW 617
           77777789999999999998888888 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MARPAAPGTP VAGWKVHIVR QLRQRDRTQK ALFLDLVPAY NHLLEKAELL DKFSEKLQLE 60
PNDVTPTTHQ GPWEEESVPD LDQVPALATL RVKWQEKEEG LRLVCGEMAY QVVEKSAALG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAGGC CAGCTGCTCC CGGTACCCCT GTTGCCGGCT GGAAAGTCCA CATTGTGCGG 60
CAGCTGCGGC AGCGGGATCG CACGCAAAAG GCACTCTTCC TGGATCTGGT GCCAGCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	68.00	0.00e+00	757.00
IUUC-Ame-011152	Astyanax mexicanus	41.30	2.00e-114	405.00
IUUC-Bta-013118	Bos taurus	82.55	0.00e+00	889.00
IUUC-Cja-020002	Callithrix jacchus	84.35	0.00e+00	914.00
IUUC-Cfa-020878	Canis familiaris	82.45	0.00e+00	902.00
IUUC-Cpo-022476	Cavia porcellus	81.82	0.00e+00	898.00
IUUC-Csa-024134	Chlorocebus sabaeus	85.83	0.00e+00	937.00
IUUC-Cho-024853	Choloepus hoffmanni	68.81	2.00e-171	595.00
IUUC-Dre-027949	Danio rerio	42.43	1.00e-127	449.00
IUUC-Dno-029683	Dasypus novemcinctus	83.71	0.00e+00	768.00
IUUC-Dor-030897	Dipodomys ordii	75.69	0.00e+00	882.00
IUUC-Ete-032957	Echinops telfairi	92.00	3.00e-126	445.00
IUUC-Eca-033303	Equus caballus	90.71	4.00e-162	563.00
IUUC-Eeu-035336	Erinaceus europaeus	71.22	7.00e-147	513.00
IUUC-Fca-036232	Felis catus	83.20	0.00e+00	966.00
IUUC-Gac-042500	Gasterosteus aculeatus	41.16	2.00e-91	330.00
IUUC-Ggo-045130	Gorilla gorilla	87.41	0.00e+00	676.00
IUUC-Hsa-046359	Homo sapiens	88.45	0.00e+00	916.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	84.78	0.00e+00	948.00
IUUC-Lch-050669	Latimeria chalumnae	53.17	7.00e-91	327.00
IUUC-Loc-052789	Lepisosteus oculatus	43.23	1.00e-115	410.00
IUUC-Laf-053699	Loxodonta africana	84.14	0.00e+00	905.00
IUUC-Mcc-055657	Macaca mulatta	80.61	0.00e+00	837.00
IUUC-Meu-056639	Macropus eugenii	49.02	5.00e-107	381.00
IUUC-Mmr-061314	Microcebus murinus	81.85	0.00e+00	856.00
IUUC-Mdo-061841	Monodelphis domestica	65.42	0.00e+00	694.00
IUUC-Mmu-064065	Mus musculus	81.68	0.00e+00	924.00
IUUC-Mpu-066742	Mustela putorius furo	82.71	0.00e+00	891.00
IUUC-Mlu-067019	Myotis lucifugus	86.07	0.00e+00	654.00
IUUC-Nle-069037	Nomascus leucogenys	86.96	0.00e+00	945.00
IUUC-Opr-071039	Ochotona princeps	79.58	0.00e+00	861.00
IUUC-Oan-073431	Ornithorhynchus anatinus	72.53	3.00e-138	484.00
IUUC-Ocu-074772	Oryctolagus cuniculus	83.22	0.00e+00	807.00
IUUC-Ola-086964	Oryzias latipes	51.92	5.00e-80	290.00
IUUC-Oar-090231	Ovis aries	78.08	0.00e+00	887.00
IUUC-Ptr-091434	Pan troglodytes	85.53	0.00e+00	870.00
IUUC-Pan-091868	Papio anubis	85.62	0.00e+00	926.00
IUUC-Psi-093652	Pelodiscus sinensis	63.11	3.00e-161	561.00
IUUC-Pfo-096960	Poecilia formosa	42.05	2.00e-100	359.00
IUUC-Pab-097776	Pongo abelii	87.79	0.00e+00	875.00
IUUC-Pca-100220	Procavia capensis	64.83	4.00e-173	601.00
IUUC-Pva-103135	Pteropus vampyrus	85.67	0.00e+00	850.00
IUUC-Rno-105529	Rattus norvegicus	80.06	0.00e+00	941.00
IUUC-Sha-107062	Sarcophilus harrisii	65.85	0.00e+00	735.00
IUUC-Sar-113109	Sorex araneus	66.27	1.00e-130	459.00
IUUC-Ssc-115271	Sus scrofa	83.87	0.00e+00	882.00
IUUC-Ttr-128267	Tursiops truncatus	87.44	0.00e+00	689.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence