iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004121

Ensembl Protein ID

ENSAPLP00000005216.1

UniProt Accession

U3ID94; U3ID94_ANAPL

Genbank Protein ID

ENSAPLP00000005216

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01101657

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000005646.1	ENSAPLT00000005844.1	ENSAPLP00000005216.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.60e-82	274.9	448	905

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCYmNS++Q+L++ +++r+ +l+     l e    +++++l+++lq lf+ l +s++ a+sp+++l+a +   + f+  +qq
   Q: 448  GLINLGNTCYMNSIIQSLFMASDFRHSVLN-----LTE----GNSQPLMTKLQWLFAFLEHSQRPAISPESFLSASW--PPWFTPGAQQ 525
           9*****************************.....432....45689***************************987..788******* PP
   S: 91   DaqEflaflldq..leeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           D++E+l++lld+  l+ee      k+ ++  ++ k+++ +++  +++  nk+li+++F+g++ ++i+cl+c nvssree f+dlsl++p
   Q: 526  DCSEYLKYLLDRqrLHEEE-----KTGKRIYQKLKESSLMSQAVEHHYLNKTLIEKMFGGKMMTKIRCLKCLNVSSREEAFTDLSLAFP 609
           **********963377777.....3334444444444556667899******************************************* PP
   S: 178  gkeetkke................................................................................. 185
             +                                                                                      
   Q: 610  PPDRH-IHgpgsasvlpveeigpqfieppenlnqvmgspwvrrkphvsgdhpaqpvpvetlgfqeagepsdplsrdavgaestkdpila 697
           88743.44689****************************************************************************** PP
   S: 186  ............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
                       s+ d+++ f ++e+l+ enky+cekc ++q+aek  +l++ P++Lil L Rfsf+ ++++r+ki ++v++p  L+l 
   Q: 698  sgeqasapkdsrSVPDLINYFLSPERLTAENKYHCEKCASLQDAEKVAELTEGPHYLILTLLRFSFDPRTMKRKKILDNVSIPVVLKLP 786
           ****************************************************************************************8 PP
   S: 263  pfctspeekqke...............kkkYeLiavvvHsG.slssGHYvayvkn........................ekgkWllfdD 311
             ++s+e ++++               ++ Y+L++vvvHsG s++sGHY++y ++                         + +W+lf+D
   Q: 787  VLVSSEE-NEDVwrhgkgrggpgssfvSVVYDLCSVVVHSGiSSESGHYYCYSREctdavphgqlrdgapkpasdkqldFEIQWYLFND 874
           6666644.444579999**********************************************99999999997766655666****** PP
   S: 312  skVtevkeeevleetg....staYvlfYkrr 338
           ++V+ ++ e+v + t+    +taYvlfY++r
   Q: 875  TRVSFSSFESVSNVTSffpkDTAYVLFYRQR 905
           *************999************985 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

AGMDKILEAV VMSSYPNNVK QGLVRRVIEA SKQPMDSEQC WSMLELCTKL YLVGDTKYKR 60
EIGKEVLEVY GHYHPEEFEE FFNVRFLLSL LQEGYGPLGK RSHYVLDYIQ LGLQFVLESP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGGGATGG ATAAGATACT GGAAGCCGTG GTGATGTCCT CCTACCCCAA CAACGTGAAG 60
CAAGGCCTTG TGAGGCGCGT CATTGAGGCA TCGAAGCAGC CCATGGACAG CGAGCAGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005070	Anolis carolinensis	69.90	0.00e+00	944.00
IUUC-Bta-012545	Bos taurus	71.31	0.00e+00	885.00
IUUC-Cja-019731	Callithrix jacchus	67.70	0.00e+00	880.00
IUUC-Cfa-020095	Canis familiaris	67.99	0.00e+00	902.00
IUUC-Cpo-021961	Cavia porcellus	64.17	0.00e+00	1010.00
IUUC-Csa-023167	Chlorocebus sabaeus	61.51	0.00e+00	1035.00
IUUC-Cin-025604	Ciona intestinalis	28.96	4.00e-45	174.00
IUUC-Dno-029186	Dasypus novemcinctus	68.02	0.00e+00	644.00
IUUC-Dor-030538	Dipodomys ordii	71.59	0.00e+00	767.00
IUUC-Eca-033279	Equus caballus	76.42	0.00e+00	746.00
IUUC-Eeu-035120	Erinaceus europaeus	52.28	0.00e+00	632.00
IUUC-Fal-037625	Ficedula albicollis	90.80	0.00e+00	1743.00
IUUC-Gga-040767	Gallus gallus	92.76	0.00e+00	1792.00
IUUC-Hsa-046124	Homo sapiens	66.91	0.00e+00	884.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	64.31	0.00e+00	1125.00
IUUC-Lch-049513	Latimeria chalumnae	63.91	0.00e+00	1180.00
IUUC-Loc-052698	Lepisosteus oculatus	59.90	0.00e+00	1102.00
IUUC-Laf-053999	Loxodonta africana	64.50	0.00e+00	1134.00
IUUC-Mcc-055266	Macaca mulatta	65.98	0.00e+00	863.00
IUUC-Meu-056906	Macropus eugenii	75.88	0.00e+00	1042.00
IUUC-Mga-059595	Meleagris gallopavo	90.10	0.00e+00	1734.00
IUUC-Mdo-062167	Monodelphis domestica	72.07	0.00e+00	1348.00
IUUC-Mmu-063298	Mus musculus	68.54	0.00e+00	889.00
IUUC-Mpu-066195	Mustela putorius furo	68.49	0.00e+00	890.00
IUUC-Mlu-067583	Myotis lucifugus	60.45	0.00e+00	841.00
IUUC-Opr-070454	Ochotona princeps	61.71	3.00e-112	399.00
IUUC-Ocu-074121	Oryctolagus cuniculus	59.86	0.00e+00	979.00
IUUC-Oga-088593	Otolemur garnettii	64.62	0.00e+00	1100.00
IUUC-Oar-090140	Ovis aries	71.15	0.00e+00	875.00
IUUC-Pan-092168	Papio anubis	61.74	0.00e+00	1035.00
IUUC-Psi-093707	Pelodiscus sinensis	84.76	0.00e+00	1608.00
IUUC-Pma-094349	Petromyzon marinus	45.75	0.00e+00	810.00
IUUC-Pab-097614	Pongo abelii	66.77	0.00e+00	881.00
IUUC-Pca-100683	Procavia capensis	64.42	0.00e+00	854.00
IUUC-Rno-105061	Rattus norvegicus	67.52	0.00e+00	887.00
IUUC-Sha-106686	Sarcophilus harrisii	75.62	0.00e+00	1029.00
IUUC-Tgu-117024	Taeniopygia guttata	89.87	0.00e+00	1728.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence