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Tag Content
iUUCD ID IUUC-Xtr-132862
Ensembl Protein ID ENSXETP00000042118.3
UniProt Accession F6Z8A1; F6Z8A1_XENTR
Genbank Protein ID ENSXETP00000042118
Protein Name Phosphoinositide phospholipase C
Genbank Nucleotide ID AAMC01016789
Gene Name plcg1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000019423.3 ENSXETT00000042118.3 ENSXETP00000042118.3
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 5.80e-12 45.6 784 841
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekl 62
           +k  v++l+dy+aq +deLt++k  +++ +  e+q++gW++g  +  gk+ + fP+n+ve++
   Q: 784  FKCSVRALFDYKAQREDELTFTKNTIIQNV--EKQEGGWWRG--DCGGKKQMwFPANYVEEI 841
           56689************************9..9*********..666655544******997 PP
   
Organism Xenopus tropicalis
Protein Sequence
(Fasta)
MESLPLLNGF APCGQSEAEL THLCRSLEVG TVMTLFYSKK SQKPERRTFQ VKLETRQVTW 60
SRVADKVEGA VDIREIKEIR PSKNSRDFDR YQEDPTVRLE QAHCFVILYG TEFRLKTLSL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-132862|UBD,SH3|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGAATCCC TGCCGCTTCT CAATGGGTTC GCTCCATGTG GGCAAAGTGA AGCCGAGCTC 60
ACCCATCTGT GCCGGAGTTT GGAGGTGGGC ACCGTCATGA CCCTCTTCTA CTCCAAGAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132862|UBD,SH3|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer
Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3
Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005622--C:intracellular
GO:0005509--F:calcium ion binding
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0001525--P:angiogenesis
GO:0048844--P:artery morphogenesis
GO:0031101--P:fin regeneration
GO:0030851--P:granulocyte differentiation
GO:0060218--P:hematopoietic stem cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0009395--P:phospholipid catabolic process
GO:0035477--P:regulation of angioblast cell migration involved in selective angioblast sprouting
GO:0008016--P:regulation of heart contraction
GO:0001570--P:vasculogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001452 Ailuropoda melanoleuca 77.85 0.00e+00 2041.00
IUUC-Aca-005291 Anolis carolinensis 78.17 0.00e+00 2006.00
IUUC-Ame-011004 Astyanax mexicanus 63.99 0.00e+00 1633.00
IUUC-Bta-012660 Bos taurus 77.72 0.00e+00 1916.00
IUUC-Cja-019206 Callithrix jacchus 77.33 0.00e+00 2019.00
IUUC-Cfa-020257 Canis familiaris 78.05 0.00e+00 1935.00
IUUC-Cpo-022391 Cavia porcellus 72.87 0.00e+00 1867.00
IUUC-Csa-024170 Chlorocebus sabaeus 78.43 0.00e+00 1504.00
IUUC-Dre-027944 Danio rerio 66.54 0.00e+00 1709.00
IUUC-Dno-029440 Dasypus novemcinctus 77.73 0.00e+00 1848.00
IUUC-Dor-031001 Dipodomys ordii 77.25 0.00e+00 2026.00
IUUC-Eca-033809 Equus caballus 78.05 0.00e+00 1938.00
IUUC-Fca-036510 Felis catus 77.97 0.00e+00 1935.00
IUUC-Fal-037541 Ficedula albicollis 78.13 0.00e+00 1826.00
IUUC-Gmo-038630 Gadus morhua 61.50 0.00e+00 1322.00
IUUC-Gga-040142 Gallus gallus 79.21 0.00e+00 2005.00
IUUC-Ggo-045063 Gorilla gorilla 78.01 0.00e+00 2044.00
IUUC-Hsa-046428 Homo sapiens 77.93 0.00e+00 2042.00
IUUC-Itr-048245 Ictidomys tridecemlineatus 78.06 0.00e+00 1999.00
IUUC-Lch-049766 Latimeria chalumnae 73.77 0.00e+00 1773.00
IUUC-Loc-052285 Lepisosteus oculatus 71.97 0.00e+00 1855.00
IUUC-Laf-053365 Loxodonta africana 77.76 0.00e+00 1929.00
IUUC-Mcc-054871 Macaca mulatta 78.02 0.00e+00 2038.00
IUUC-Meu-056724 Macropus eugenii 73.08 0.00e+00 1768.00
IUUC-Mga-059329 Meleagris gallopavo 77.24 0.00e+00 1871.00
IUUC-Mmr-061110 Microcebus murinus 77.79 0.00e+00 2032.00
IUUC-Mdo-062448 Monodelphis domestica 78.15 0.00e+00 2042.00
IUUC-Mmu-063565 Mus musculus 77.79 0.00e+00 2025.00
IUUC-Mpu-066683 Mustela putorius furo 77.93 0.00e+00 2044.00
IUUC-Mlu-067779 Myotis lucifugus 77.62 0.00e+00 1931.00
IUUC-Nle-069219 Nomascus leucogenys 79.66 0.00e+00 1726.00
IUUC-Opr-070766 Ochotona princeps 77.19 0.00e+00 1196.00
IUUC-Ont-072524 Oreochromis niloticus 69.64 0.00e+00 1800.00
IUUC-Oan-073214 Ornithorhynchus anatinus 82.42 7.00e-41 159.00
IUUC-Ocu-074361 Oryctolagus cuniculus 76.83 0.00e+00 2002.00
IUUC-Ola-086820 Oryzias latipes 68.06 0.00e+00 1810.00
IUUC-Oga-088172 Otolemur garnettii 78.30 0.00e+00 2048.00
IUUC-Oar-090306 Ovis aries 75.33 0.00e+00 1852.00
IUUC-Ptr-090682 Pan troglodytes 78.01 0.00e+00 2044.00
IUUC-Pan-092835 Papio anubis 78.58 0.00e+00 1465.00
IUUC-Psi-093344 Pelodiscus sinensis 77.42 0.00e+00 1996.00
IUUC-Pfo-096984 Poecilia formosa 68.59 0.00e+00 1771.00
IUUC-Pab-097871 Pongo abelii 78.16 0.00e+00 2006.00
IUUC-Pca-100772 Procavia capensis 72.65 0.00e+00 1868.00
IUUC-Pva-102790 Pteropus vampyrus 78.62 0.00e+00 2005.00
IUUC-Rno-105974 Rattus norvegicus 77.92 0.00e+00 2045.00
IUUC-Sar-112995 Sorex araneus 76.38 0.00e+00 1965.00
IUUC-Ssc-115360 Sus scrofa 77.76 0.00e+00 2036.00
IUUC-Tgu-116585 Taeniopygia guttata 76.27 0.00e+00 1892.00
IUUC-Tru-117742 Takifugu rubripes 69.71 0.00e+00 1838.00
IUUC-Tsy-119259 Tarsius syrichta 83.33 0.00e+00 735.00
IUUC-Tbe-127504 Tupaia belangeri 73.18 0.00e+00 1015.00
IUUC-Ttr-128392 Tursiops truncatus 47.22 0.00e+00 1155.00
Created Date 25-Jun-2017

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