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Tag Content
iUUCD ID IUUC-Ssc-115877
Ensembl Protein ID ENSSSCP00000027635.1
UniProt Accession I3LU36; I3LU36_PIG
Genbank Protein ID ENSSSCP00000027635
Protein Name Uncharacterized protein
Genbank Nucleotide ID FP236691
Gene Name USP25
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000024623.1 ENSSSCT00000022689.1 ENSSSCP00000027635.1
ENSSSCG00000024623.1 ENSSSCT00000027672.1 ENSSSCP00000020389.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.30e-63 213.8 168 657
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+r+l+l+    ++ ++l+++++++++ +++++l+ lf+ l+ +k+k+v+p++ +++lk++ ++ +
   Q: 168  VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNykppSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRAVEILKDAFKS-N 255
           6******************************99988889999999999999*******************************99997.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
            ++qqD++Ef++ lld le+++++                  + +ee +++k k+++++lF g++    + +  +++ + +e f +++l
   Q: 256  DSQQQDVSEFTHKLLDWLEDAFQM------------------KAEEETDEEKPKNPMVELFYGRFLAVGVLE--GKKFENTEMFGQYPL 324
           **********************33..................123456788999************777664..444556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++e+  k+    +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp+ L l++
   Q: 325  QVNGFK-----DLHECLEAAMIEGEIES---LHSENSGKS---GQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDR 402
           ******.....9**************96...999998865...589******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++++                                                                                     
   Q: 403  YMHRnreitrikreeikrlkdyltvlqqrlerylsygsgpkrfplvdvlqyalefasskpvctspvddidasspssgsipsqtlpryym 491
           ****8888888887777777777777777777777777777777777777777777777777777777777776666666666666666 PP
   S: 268  ..........................peekqke........................................................ 274
                                     +     +                                                        
   Q: 492  hqpficenttelpstspasiaaissrS-----Vihkpftqsrippdlpmhpaprhiteeelsvlesclhrwrteiendtrdlqesisri 575
           666666666666555555555555550.....055555555555555555555555555666666666666666666667777777888 PP
   S: 275  ..............kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                         ++ Y+L+av+vH+G+++ GHY+ay+ +++++ W++++D  Vt++++ee ++++      ++aY+l+Y 
   Q: 576  hrtielmysdksmiQVPYRLHAVLVHEGQANAGHYWAYIFDHRENrWMKYNDIAVTKSSWEELVRDSFggyrnASAYCLMYI 657
           88888888888888**************************965556***************99997779************6 PP
   
Organism Sus scrofa
Protein Sequence
(Fasta)
MILFLSLNRI GSRNHQQTFL NQLREITGIN DAQILQQALK DSNGNLELAV AFLTAKNAKT 60
PQQEETAYYQ TALPGNDRYI SVGSQADTNV IDLTGDDKDD LQRAIALSLA ESNRAFRETG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-115877|DUB,USP|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGATTCTTT TTCTTTCCCT AAATAGGATA GGATCTCGTA ATGTAATATA TCCACCTAGT 60
GTCTCACCTG CCAAAAGCAT GTTTTTTTTC CTCAGACATC CTAGGTGCTT GGATGCTGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-115877|DUB,USP|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1904293--P:negative regulation of ERAD pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001340 Ailuropoda melanoleuca 92.05 0.00e+00 1949.00
IUUC-Apl-004030 Anas platyrhynchos 81.38 0.00e+00 1800.00
IUUC-Aca-004753 Anolis carolinensis 63.20 0.00e+00 988.00
IUUC-Ame-010624 Astyanax mexicanus 69.65 0.00e+00 1087.00
IUUC-Bta-013166 Bos taurus 95.95 0.00e+00 1982.00
IUUC-Cel-018346 Caenorhabditis elegans 27.14 8.00e-29 122.00
IUUC-Cja-019150 Callithrix jacchus 93.90 0.00e+00 1390.00
IUUC-Cfa-020649 Canis familiaris 93.65 0.00e+00 1406.00
IUUC-Cpo-021807 Cavia porcellus 90.50 0.00e+00 2014.00
IUUC-Csa-023388 Chlorocebus sabaeus 94.74 0.00e+00 1417.00
IUUC-Cho-024343 Choloepus hoffmanni 80.72 0.00e+00 982.00
IUUC-Cin-025302 Ciona intestinalis 37.25 1.00e-95 343.00
IUUC-Csv-025911 Ciona savignyi 35.02 2.00e-132 466.00
IUUC-Cgl-026575 Colletotrichum gloeosporioides 55.32 1.00e-10 62.40
IUUC-Cme-027167 Cyanidioschyzon merolae 24.82 2.00e-14 74.30
IUUC-Dre-028016 Danio rerio 77.07 0.00e+00 1177.00
IUUC-Dno-029495 Dasypus novemcinctus 90.43 0.00e+00 1392.00
IUUC-Dor-030948 Dipodomys ordii 79.39 0.00e+00 1414.00
IUUC-Eca-034300 Equus caballus 48.75 0.00e+00 953.00
IUUC-Eeu-034458 Erinaceus europaeus 48.33 0.00e+00 864.00
IUUC-Fca-035876 Felis catus 94.69 0.00e+00 1986.00
IUUC-Fal-036762 Ficedula albicollis 82.11 0.00e+00 1095.00
IUUC-Gmo-039490 Gadus morhua 71.13 0.00e+00 1521.00
IUUC-Gga-040817 Gallus gallus 78.22 0.00e+00 1746.00
IUUC-Gac-042473 Gasterosteus aculeatus 70.43 0.00e+00 1550.00
IUUC-Ggo-044939 Gorilla gorilla 89.95 0.00e+00 1878.00
IUUC-Hsa-046204 Homo sapiens 94.26 0.00e+00 1940.00
IUUC-Kpa-049349 Komagataella pastoris 28.12 2.00e-10 62.00
IUUC-Lch-049572 Latimeria chalumnae 77.34 0.00e+00 1206.00
IUUC-Loc-052070 Lepisosteus oculatus 74.09 0.00e+00 1190.00
IUUC-Lma-053078 Leptosphaeria maculans 30.56 4.00e-12 67.40
IUUC-Laf-054426 Loxodonta africana 94.40 0.00e+00 1819.00
IUUC-Mcc-055858 Macaca mulatta 94.03 0.00e+00 1422.00
IUUC-Meu-056416 Macropus eugenii 41.49 0.00e+00 748.00
IUUC-Mga-059808 Meleagris gallopavo 83.26 0.00e+00 1814.00
IUUC-Mmr-060987 Microcebus murinus 94.41 0.00e+00 1404.00
IUUC-Mmu-064245 Mus musculus 90.87 0.00e+00 1955.00
IUUC-Mpu-066304 Mustela putorius furo 94.22 0.00e+00 1404.00
IUUC-Mlu-067139 Myotis lucifugus 94.03 0.00e+00 1995.00
IUUC-Nle-069075 Nomascus leucogenys 94.36 0.00e+00 1939.00
IUUC-Opr-070888 Ochotona princeps 59.85 3.00e-91 330.00
IUUC-Ont-072150 Oreochromis niloticus 75.28 0.00e+00 1177.00
IUUC-Oan-073054 Ornithorhynchus anatinus 78.43 0.00e+00 1685.00
IUUC-Ocu-074102 Oryctolagus cuniculus 90.67 0.00e+00 1396.00
IUUC-Ola-086529 Oryzias latipes 67.82 0.00e+00 1472.00
IUUC-Oga-088939 Otolemur garnettii 94.70 0.00e+00 1977.00
IUUC-Oar-090266 Ovis aries 95.38 0.00e+00 1411.00
IUUC-Ptr-090546 Pan troglodytes 94.07 0.00e+00 1936.00
IUUC-Pan-092311 Papio anubis 93.90 0.00e+00 1420.00
IUUC-Psi-093459 Pelodiscus sinensis 89.14 0.00e+00 1150.00
IUUC-Pma-094250 Petromyzon marinus 40.00 3.00e-53 201.00
IUUC-Pfo-096726 Poecilia formosa 75.28 0.00e+00 1164.00
IUUC-Pab-097608 Pongo abelii 92.00 0.00e+00 1919.00
IUUC-Pca-100718 Procavia capensis 89.38 0.00e+00 1217.00
IUUC-Pva-103150 Pteropus vampyrus 89.87 0.00e+00 1457.00
IUUC-Rno-105727 Rattus norvegicus 91.45 0.00e+00 1922.00
IUUC-Sha-107051 Sarcophilus harrisii 86.92 0.00e+00 1842.00
IUUC-Sar-113097 Sorex araneus 84.45 0.00e+00 1805.00
IUUC-Tgu-117473 Taeniopygia guttata 77.06 0.00e+00 1671.00
IUUC-Tru-118135 Takifugu rubripes 65.44 0.00e+00 1393.00
IUUC-Tsy-119471 Tarsius syrichta 87.28 0.00e+00 1763.00
IUUC-Tni-120139 Tetraodon nigroviridis 66.83 0.00e+00 1309.00
IUUC-Tbe-127549 Tupaia belangeri 88.04 0.00e+00 1856.00
IUUC-Ttr-128896 Tursiops truncatus 88.40 0.00e+00 1881.00
IUUC-Vpa-130500 Vicugna pacos 93.05 0.00e+00 1318.00
IUUC-Xtr-132896 Xenopus tropicalis 78.79 0.00e+00 1712.00
Created Date 25-Jun-2017

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