iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088215

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03038520

Gene Name

RFWD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000015465.2	ENSOGAT00000015469.2	ENSOGAP00000013848.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-21	75.1	474	503
E3 activity/RING/RING	2.00e-06	28.2	140	178

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 474  NSKISCISWssYHkNLLASSDYEGTVILWD 503
           689******9622599************** PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 140  CPICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 178
           ********99.888***********9555......999999****6 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MSGSRQAGSG SSGTSPGSSA ASSVTSASSS LSSSPSPPSV AASTPALVSS GAAGAAASGS 60
VGGQARPVLV AAAVSGSGGG SGGGAVSAGL SRLSCAARPS ASVGGSSSSL GSGSRKRPLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCGTGGCG GCTACGGCCT CAACAGCGGT AGTGGCTTCT ACTCGGCTTT TTTAGTTTCC 60
TCCGCCCCCT CCCGTCGGAC TCTGTTGTGT GGTTGCCTTG AAAAAACCAA CTTTATTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	39.65	2.00e-121	429.00
IUUC-Aml-001265	Ailuropoda melanoleuca	98.06	0.00e+00	1227.00
IUUC-Atr-002460	Amborella trichopoda	38.18	4.00e-120	425.00
IUUC-Apl-003796	Anas platyrhynchos	98.45	0.00e+00	1157.00
IUUC-Aca-005078	Anolis carolinensis	95.48	0.00e+00	1185.00
IUUC-Aly-006014	Arabidopsis lyrata	39.65	2.00e-125	442.00
IUUC-Ath-007636	Arabidopsis thaliana	39.55	9.00e-125	440.00
IUUC-Ame-011176	Astyanax mexicanus	74.21	7.00e-70	258.00
IUUC-Bta-012595	Bos taurus	97.36	0.00e+00	1236.00
IUUC-Bdi-014152	Brachypodium distachyon	38.76	5.00e-124	438.00
IUUC-Bol-016380	Brassica oleracea	40.00	2.00e-126	446.00
IUUC-Bra-017690	Brassica rapa	38.84	6.00e-121	428.00
IUUC-Cja-018926	Callithrix jacchus	97.20	0.00e+00	1229.00
IUUC-Cfa-021088	Canis familiaris	97.05	0.00e+00	1235.00
IUUC-Cpo-022442	Cavia porcellus	98.89	0.00e+00	1226.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.45	3.00e-33	135.00
IUUC-Csa-024119	Chlorocebus sabaeus	96.59	0.00e+00	1225.00
IUUC-Cho-024883	Choloepus hoffmanni	86.07	5.00e-105	375.00
IUUC-Cin-025375	Ciona intestinalis	54.63	0.00e+00	660.00
IUUC-Cme-027350	Cyanidioschyzon merolae	40.81	4.00e-75	276.00
IUUC-Dre-028453	Danio rerio	85.62	0.00e+00	1056.00
IUUC-Dno-029887	Dasypus novemcinctus	96.72	0.00e+00	1222.00
IUUC-Dor-031110	Dipodomys ordii	77.87	0.00e+00	896.00
IUUC-Ete-033016	Echinops telfairi	82.45	0.00e+00	1015.00
IUUC-Eca-034403	Equus caballus	99.31	0.00e+00	1161.00
IUUC-Eeu-034690	Erinaceus europaeus	84.35	0.00e+00	960.00
IUUC-Fca-036475	Felis catus	98.62	0.00e+00	1161.00
IUUC-Fal-037189	Ficedula albicollis	96.47	0.00e+00	1164.00
IUUC-Gmo-039245	Gadus morhua	85.29	0.00e+00	1036.00
IUUC-Gga-040806	Gallus gallus	96.28	0.00e+00	1212.00
IUUC-Gac-042177	Gasterosteus aculeatus	86.06	0.00e+00	1076.00
IUUC-Gma-044187	Glycine max	39.75	7.00e-123	434.00
IUUC-Ggo-044430	Gorilla gorilla	98.73	0.00e+00	932.00
IUUC-Hsa-045853	Homo sapiens	97.20	0.00e+00	1231.00
IUUC-Hvu-047750	Hordeum vulgare	37.02	5.00e-88	320.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	100.00	8.00e-145	505.00
IUUC-Lch-050420	Latimeria chalumnae	90.11	0.00e+00	1125.00
IUUC-Lpe-051219	Leersia perrieri	38.85	2.00e-122	432.00
IUUC-Loc-052728	Lepisosteus oculatus	89.34	0.00e+00	1080.00
IUUC-Laf-053775	Loxodonta africana	96.57	0.00e+00	1233.00
IUUC-Meu-056595	Macropus eugenii	77.93	2.00e-177	616.00
IUUC-Mtr-058555	Medicago truncatula	40.61	2.00e-129	456.00
IUUC-Mga-059646	Meleagris gallopavo	97.95	0.00e+00	1157.00
IUUC-Mmr-060990	Microcebus murinus	97.50	0.00e+00	1234.00
IUUC-Mdo-062287	Monodelphis domestica	96.94	0.00e+00	1222.00
IUUC-Mmu-064097	Mus musculus	96.89	0.00e+00	1234.00
IUUC-Mac-065240	Musa acuminata	40.82	3.00e-130	459.00
IUUC-Mpu-066612	Mustela putorius furo	99.83	0.00e+00	1166.00
IUUC-Mlu-067967	Myotis lucifugus	99.48	0.00e+00	1161.00
IUUC-Nle-069543	Nomascus leucogenys	97.36	0.00e+00	1235.00
IUUC-Opr-070366	Ochotona princeps	83.88	0.00e+00	716.00
IUUC-Ont-071522	Oreochromis niloticus	85.74	0.00e+00	1065.00
IUUC-Oan-073409	Ornithorhynchus anatinus	98.80	0.00e+00	1163.00
IUUC-Ocu-073756	Oryctolagus cuniculus	99.20	0.00e+00	1233.00
IUUC-Oba-075149	Oryza barthii	38.79	4.00e-122	432.00
IUUC-Obr-076563	Oryza brachyantha	39.17	4.00e-122	431.00
IUUC-Ogl-077701	Oryza glaberrima	38.47	2.00e-122	433.00
IUUC-Ogu-078383	Oryza glumaepatula	38.47	2.00e-122	433.00
IUUC-Oin-079965	Oryza indica	36.58	1.00e-108	387.00
IUUC-Olo-080639	Oryza longistaminata	38.32	3.00e-120	426.00
IUUC-Ome-081821	Oryza meridionalis	38.24	4.00e-110	392.00
IUUC-Oni-082622	Oryza nivara	38.47	2.00e-122	433.00
IUUC-Opu-083295	Oryza punctata	38.47	4.00e-122	431.00
IUUC-Oru-084661	Oryza rufipogon	38.47	2.00e-122	433.00
IUUC-Osa-085766	Oryza sativa	38.47	2.00e-122	433.00
IUUC-Ola-086727	Oryzias latipes	85.71	0.00e+00	1082.00
IUUC-Olu-087702	Ostreococcus lucimarinus	43.10	1.00e-65	243.00
IUUC-Oar-089880	Ovis aries	97.97	0.00e+00	1238.00
IUUC-Ptr-090597	Pan troglodytes	97.20	0.00e+00	1231.00
IUUC-Pan-091987	Papio anubis	97.36	0.00e+00	1235.00
IUUC-Psi-094033	Pelodiscus sinensis	95.93	0.00e+00	1140.00
IUUC-Pma-094587	Petromyzon marinus	70.56	0.00e+00	804.00
IUUC-Ppa-095256	Physcomitrella patens	39.18	4.00e-127	448.00
IUUC-Pfo-097388	Poecilia formosa	84.73	0.00e+00	1043.00
IUUC-Pab-098029	Pongo abelii	97.20	0.00e+00	1231.00
IUUC-Pop-099319	Populus trichocarpa	38.44	8.00e-126	444.00
IUUC-Pca-100846	Procavia capensis	88.75	0.00e+00	1116.00
IUUC-Ppe-101250	Prunus persica	38.52	2.00e-116	413.00
IUUC-Pva-102407	Pteropus vampyrus	96.89	0.00e+00	1224.00
IUUC-Rno-105312	Rattus norvegicus	96.89	0.00e+00	1233.00
IUUC-Sha-106514	Sarcophilus harrisii	98.92	0.00e+00	776.00
IUUC-Smo-109418	Selaginella moellendorffii	39.33	6.00e-125	441.00
IUUC-Sit-110248	Setaria italica	38.44	2.00e-123	436.00
IUUC-Sly-110964	Solanum lycopersicum	40.51	1.00e-127	450.00
IUUC-Stu-112882	Solanum tuberosum	40.61	1.00e-128	453.00
IUUC-Sar-113230	Sorex araneus	70.80	0.00e+00	781.00
IUUC-Sbi-113962	Sorghum bicolor	36.52	4.00e-118	419.00
IUUC-Ssc-115987	Sus scrofa	99.41	0.00e+00	629.00
IUUC-Tgu-116471	Taeniopygia guttata	96.60	0.00e+00	1209.00
IUUC-Tru-118231	Takifugu rubripes	85.53	0.00e+00	1028.00
IUUC-Tsy-119415	Tarsius syrichta	96.63	0.00e+00	1144.00
IUUC-Tni-120893	Tetraodon nigroviridis	85.55	0.00e+00	1036.00
IUUC-Tca-121703	Theobroma cacao	41.03	3.00e-125	442.00
IUUC-Tae-125317	Triticum aestivum	40.73	2.00e-129	456.00
IUUC-Tur-126557	Triticum urartu	40.36	2.00e-124	439.00
IUUC-Tbe-127253	Tupaia belangeri	69.10	0.00e+00	820.00
IUUC-Ttr-129100	Tursiops truncatus	95.29	0.00e+00	1112.00
IUUC-Vpa-130613	Vicugna pacos	90.57	0.00e+00	1069.00
IUUC-Vvi-130880	Vitis vinifera	40.70	1.00e-118	420.00
IUUC-Xtr-132033	Xenopus tropicalis	93.55	0.00e+00	1209.00
IUUC-Xma-133421	Xiphophorus maculatus	84.57	0.00e+00	1040.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence