iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036735

Ensembl Protein ID

ENSFALP00000003821.1

UniProt Accession

U3JM17; U3JM17_FICAL

Genbank Protein ID

ENSFALP00000003821

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021520

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000003668.1	ENSFALT00000003836.1	ENSFALP00000003821.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.00e-09	36.6	779	823

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gg+    l++CekC ++fH  C+ ++   ++p+ e wiC+ Cr
   Q: 779  DWCAVCQNGGK----LLCCEKCPKVFHLSCHVPT-LMSFPSGE-WICTFCR 823
           79*********....*******************.*******8.******8 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MPCPRDKDFH RMEGTTEGHL ARPPFSSVVI LEHTAQDRVQ AALEHLQRGR LHTLSGQPVP 60
EHGHADSKEV FRHIQKENSP FWTDAVGVIR CPICGQECAE RHIIDNFFVK DTTEVPSSTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCTGTC CAAGGGACAA AGACTTCCAC AGAATGGAAG GGACCACAGA GGGTCATCTG 60
GCCCGACCTC CCTTCTCAAG CGTGGTCATT CTAGAGCACA CGGCACAGGA CCGTGTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

KEGG

fab:101819536

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	79.70	0.00e+00	1288.00
IUUC-Apl-003697	Anas platyrhynchos	90.26	0.00e+00	1470.00
IUUC-Bta-013282	Bos taurus	79.34	0.00e+00	1291.00
IUUC-Cja-018920	Callithrix jacchus	79.27	0.00e+00	1313.00
IUUC-Cfa-020984	Canis familiaris	79.49	0.00e+00	1298.00
IUUC-Cpo-022035	Cavia porcellus	78.33	0.00e+00	1336.00
IUUC-Csa-024208	Chlorocebus sabaeus	79.81	0.00e+00	1318.00
IUUC-Dno-029145	Dasypus novemcinctus	80.04	0.00e+00	1348.00
IUUC-Dor-030396	Dipodomys ordii	75.39	0.00e+00	976.00
IUUC-Ete-032414	Echinops telfairi	74.84	0.00e+00	761.00
IUUC-Eca-033489	Equus caballus	80.36	0.00e+00	1310.00
IUUC-Eeu-034654	Erinaceus europaeus	73.63	2.00e-163	569.00
IUUC-Fca-035844	Felis catus	77.19	0.00e+00	1187.00
IUUC-Gga-041124	Gallus gallus	89.82	0.00e+00	1454.00
IUUC-Ggo-044542	Gorilla gorilla	79.91	0.00e+00	1318.00
IUUC-Hsa-046785	Homo sapiens	79.81	0.00e+00	1316.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	79.91	0.00e+00	1304.00
IUUC-Laf-054279	Loxodonta africana	78.49	0.00e+00	1308.00
IUUC-Mcc-055668	Macaca mulatta	79.91	0.00e+00	1318.00
IUUC-Meu-056195	Macropus eugenii	68.79	0.00e+00	685.00
IUUC-Mga-059272	Meleagris gallopavo	88.96	0.00e+00	1433.00
IUUC-Mmr-060936	Microcebus murinus	78.74	0.00e+00	1291.00
IUUC-Mdo-062848	Monodelphis domestica	81.04	0.00e+00	1331.00
IUUC-Mmu-063598	Mus musculus	78.87	0.00e+00	1269.00
IUUC-Mpu-066272	Mustela putorius furo	79.59	0.00e+00	1293.00
IUUC-Mlu-067958	Myotis lucifugus	78.80	0.00e+00	1308.00
IUUC-Nle-069375	Nomascus leucogenys	79.91	0.00e+00	1318.00
IUUC-Oan-073393	Ornithorhynchus anatinus	76.12	0.00e+00	923.00
IUUC-Ocu-074873	Oryctolagus cuniculus	77.37	0.00e+00	1308.00
IUUC-Oga-088692	Otolemur garnettii	78.85	0.00e+00	1272.00
IUUC-Oar-090160	Ovis aries	79.74	0.00e+00	1295.00
IUUC-Ptr-090756	Pan troglodytes	79.81	0.00e+00	1316.00
IUUC-Pan-091719	Papio anubis	79.91	0.00e+00	1317.00
IUUC-Psi-093433	Pelodiscus sinensis	85.12	0.00e+00	1422.00
IUUC-Pab-098599	Pongo abelii	78.63	0.00e+00	1290.00
IUUC-Pca-100540	Procavia capensis	75.51	0.00e+00	798.00
IUUC-Pva-102478	Pteropus vampyrus	73.82	0.00e+00	1137.00
IUUC-Sha-106740	Sarcophilus harrisii	76.60	0.00e+00	1245.00
IUUC-Sar-113615	Sorex araneus	77.41	0.00e+00	1110.00
IUUC-Tgu-117368	Taeniopygia guttata	94.58	0.00e+00	1581.00
IUUC-Tsy-118904	Tarsius syrichta	79.16	0.00e+00	1312.00
IUUC-Tbe-127354	Tupaia belangeri	64.27	1.00e-148	520.00
IUUC-Ttr-128983	Tursiops truncatus	75.27	0.00e+00	929.00
IUUC-Vpa-130420	Vicugna pacos	78.52	0.00e+00	1274.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence