iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	5.10e-12	46.4	37	100

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkld 66
           +Dv+l+v+++ef+ah++vLaa+S++F   + ++ ++    l v + + v +  f  ll+F Yt kl 
   Q: 37   CDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKD---DLVVSLPEeVTARGFGPLLQFAYTAKLL 100
           9*****************************888777...489****66****************985 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSVDEKPDSP MYVYESTVHC ANILLGLNDQ RKKDILCDVT LIVERKEFRA HRAVLAACSE 60
YFWQALVGQT KDDLVVSLPE EVTARGFGPL LQFAYTAKLL LSRENIREVI RCAEFLRMHN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAAGTGAGG GTTCCGAAAC AAGAAGGACC TTCAGGAGCT TCTTCACACT GTGACATGTC 60
TGATCCCTTG TGCCCGTCCC TGCAGCATGA ACAAGGTAAA GGACGCTTTG AATATGCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR000210--BTB/POZ_dom
IPR004827--bZIP
IPR004826--bZIP_Maf
IPR011333--SKP1/BTB/POZ
IPR008917--TF_DNA-bd

PROSITE

PS50097--BTB
PS50217--BZIP
PS00036--BZIP_BASIC

Pfam

PF00651--BTB
PF03131--bZIP_Maf

SMART

SM00338--BRLZ
SM00225--BTB

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0001206--F:transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0016567--P:protein ubiquitination
GO:1902593--P:single-organism nuclear import
GO:0006366--P:transcription from RNA polymerase II promoter

KEGG

rno:313125

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001451	Ailuropoda melanoleuca	88.93	0.00e+00	1374.00
IUUC-Apl-003617	Anas platyrhynchos	70.86	0.00e+00	1087.00
IUUC-Aca-004829	Anolis carolinensis	73.90	0.00e+00	1136.00
IUUC-Ame-011958	Astyanax mexicanus	50.70	6.00e-176	610.00
IUUC-Bta-013001	Bos taurus	87.65	0.00e+00	1386.00
IUUC-Cja-019232	Callithrix jacchus	89.22	0.00e+00	1375.00
IUUC-Cfa-020872	Canis familiaris	87.18	0.00e+00	1362.00
IUUC-Cpo-022203	Cavia porcellus	82.69	4.00e-178	618.00
IUUC-Csa-023057	Chlorocebus sabaeus	89.42	0.00e+00	1406.00
IUUC-Cho-025090	Choloepus hoffmanni	84.82	0.00e+00	650.00
IUUC-Csv-026178	Ciona savignyi	41.67	1.00e-25	111.00
IUUC-Dre-028449	Danio rerio	56.94	0.00e+00	751.00
IUUC-Dno-029780	Dasypus novemcinctus	88.23	0.00e+00	1385.00
IUUC-Dor-030786	Dipodomys ordii	86.80	0.00e+00	1343.00
IUUC-Eca-033802	Equus caballus	89.54	0.00e+00	1410.00
IUUC-Eeu-035187	Erinaceus europaeus	84.55	0.00e+00	1357.00
IUUC-Fca-036490	Felis catus	79.38	0.00e+00	1231.00
IUUC-Fal-037655	Ficedula albicollis	76.55	0.00e+00	1224.00
IUUC-Gga-041057	Gallus gallus	76.67	0.00e+00	1231.00
IUUC-Gac-041702	Gasterosteus aculeatus	56.69	0.00e+00	747.00
IUUC-Ggo-044982	Gorilla gorilla	89.30	0.00e+00	1387.00
IUUC-Hsa-045852	Homo sapiens	89.52	0.00e+00	1387.00
IUUC-Itr-048706	Ictidomys tridecemlineatus	90.16	0.00e+00	1397.00
IUUC-Lch-049448	Latimeria chalumnae	67.14	0.00e+00	1008.00
IUUC-Loc-052840	Lepisosteus oculatus	60.07	0.00e+00	836.00
IUUC-Laf-054135	Loxodonta africana	85.19	0.00e+00	1320.00
IUUC-Mcc-055251	Macaca mulatta	89.55	0.00e+00	1385.00
IUUC-Meu-056518	Macropus eugenii	71.38	0.00e+00	1078.00
IUUC-Mga-060073	Meleagris gallopavo	76.55	0.00e+00	1227.00
IUUC-Mmr-061770	Microcebus murinus	89.06	0.00e+00	1360.00
IUUC-Mdo-062541	Monodelphis domestica	78.19	0.00e+00	1256.00
IUUC-Mmu-063594	Mus musculus	97.26	0.00e+00	1537.00
IUUC-Mpu-066651	Mustela putorius furo	88.45	0.00e+00	1336.00
IUUC-Mlu-067438	Myotis lucifugus	75.49	0.00e+00	1143.00
IUUC-Nle-069208	Nomascus leucogenys	89.17	0.00e+00	1406.00
IUUC-Ont-072358	Oreochromis niloticus	55.33	0.00e+00	747.00
IUUC-Ola-087475	Oryzias latipes	56.47	0.00e+00	759.00
IUUC-Oga-088512	Otolemur garnettii	85.36	0.00e+00	1267.00
IUUC-Oar-090318	Ovis aries	87.31	0.00e+00	1386.00
IUUC-Ptr-091546	Pan troglodytes	86.07	0.00e+00	1313.00
IUUC-Pan-092159	Papio anubis	89.43	0.00e+00	1385.00
IUUC-Psi-093436	Pelodiscus sinensis	76.90	0.00e+00	1234.00
IUUC-Pfo-097497	Poecilia formosa	56.22	0.00e+00	708.00
IUUC-Pab-097676	Pongo abelii	90.13	0.00e+00	1415.00
IUUC-Pca-100624	Procavia capensis	88.65	6.00e-121	428.00
IUUC-Pva-102757	Pteropus vampyrus	83.97	0.00e+00	1329.00
IUUC-Sha-107171	Sarcophilus harrisii	77.85	0.00e+00	1199.00
IUUC-Ssc-116190	Sus scrofa	88.34	0.00e+00	1153.00
IUUC-Tgu-116828	Taeniopygia guttata	76.90	0.00e+00	1230.00
IUUC-Tsy-119088	Tarsius syrichta	83.43	0.00e+00	751.00
IUUC-Tbe-127807	Tupaia belangeri	87.08	0.00e+00	1124.00
IUUC-Ttr-128874	Tursiops truncatus	86.21	0.00e+00	1368.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence