iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-024204

Ensembl Protein ID

ENSCSAP00000011635.1

UniProt Accession

A0A0D9RSP6; A0A0D9RSP6_CHLSB

Genbank Protein ID

ENSCSAP00000011635

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01148028

Gene Name

VAV2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000015568.1	ENSCSAT00000013643.1	ENSCSAP00000011635.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-17	63.5	841	892

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + y++ a +  eL+l++Gdvv++ +    d+gW+kg  e++g+ G fP+ +ve+
   Q: 841  ARYNFAARDMRELSLREGDVVRIYSRIGGDQGWWKG--ETNGRIGWFPSTYVEE 892
           67**********************************..9*************86 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MEQWRQCGRW LIDCKVLPPN HRVVWPSAVV FDLAQALRDG VLLCQLLHNL SPGSIDLKDI 60
NFRPQMSQFL CLKNIRTFLK VCHDKFGLRN SELFDPFDLF DVRDFGKVIS AVSRLSLHSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCGACTGG CTGCGTGGAG CCCGGCCCGG GGCCCGCGGG CACTTGCGTG TGTGAAGCGG 60
GGAGATCCGG CGCGCTGCCC GTTGCCCGCC CCGCGGCCGC ACGTGGGCGG GAGCGGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0016477--P:cell migration
GO:0030032--P:lamellipodium assembly
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0030193--P:regulation of blood coagulation
GO:0008361--P:regulation of cell size
GO:0010468--P:regulation of gene expression
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

KEGG

csab:103239674

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	91.20	0.00e+00	1473.00
IUUC-Apl-003262	Anas platyrhynchos	87.83	0.00e+00	1523.00
IUUC-Aca-004628	Anolis carolinensis	64.30	0.00e+00	901.00
IUUC-Ath-007352	Arabidopsis thaliana	38.60	7.00e-04	39.30
IUUC-Ame-011608	Astyanax mexicanus	77.78	0.00e+00	1415.00
IUUC-Bta-013147	Bos taurus	90.09	0.00e+00	1299.00
IUUC-Cel-018578	Caenorhabditis elegans	27.34	1.00e-94	341.00
IUUC-Cja-018877	Callithrix jacchus	91.57	0.00e+00	1420.00
IUUC-Cfa-020315	Canis familiaris	88.83	0.00e+00	1239.00
IUUC-Cpo-021543	Cavia porcellus	89.00	0.00e+00	1315.00
IUUC-Cin-025115	Ciona intestinalis	35.64	5.00e-143	501.00
IUUC-Csv-025995	Ciona savignyi	35.20	4.00e-144	505.00
IUUC-Dre-028308	Danio rerio	80.13	0.00e+00	1456.00
IUUC-Dno-029584	Dasypus novemcinctus	84.85	0.00e+00	1136.00
IUUC-Dor-031014	Dipodomys ordii	79.83	0.00e+00	1210.00
IUUC-Eca-033448	Equus caballus	91.29	0.00e+00	1605.00
IUUC-Eeu-035182	Erinaceus europaeus	84.29	0.00e+00	679.00
IUUC-Fca-035460	Felis catus	89.48	0.00e+00	1313.00
IUUC-Fal-036684	Ficedula albicollis	88.79	0.00e+00	1574.00
IUUC-Gmo-038816	Gadus morhua	72.18	0.00e+00	1065.00
IUUC-Gga-040999	Gallus gallus	85.71	0.00e+00	1510.00
IUUC-Gac-041353	Gasterosteus aculeatus	73.37	0.00e+00	1115.00
IUUC-Ggo-044558	Gorilla gorilla	97.32	0.00e+00	1678.00
IUUC-Hsa-046208	Homo sapiens	97.66	0.00e+00	1683.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	86.70	0.00e+00	1188.00
IUUC-Loc-052827	Lepisosteus oculatus	79.67	0.00e+00	1451.00
IUUC-Laf-054009	Loxodonta africana	88.95	0.00e+00	1538.00
IUUC-Mcc-055054	Macaca mulatta	97.99	0.00e+00	1688.00
IUUC-Mga-060106	Meleagris gallopavo	88.50	0.00e+00	1536.00
IUUC-Mmr-061118	Microcebus murinus	91.29	0.00e+00	1583.00
IUUC-Mdo-062380	Monodelphis domestica	84.55	0.00e+00	1284.00
IUUC-Mmu-063135	Mus musculus	92.75	0.00e+00	1632.00
IUUC-Mpu-066135	Mustela putorius furo	87.70	0.00e+00	1414.00
IUUC-Nle-069465	Nomascus leucogenys	88.96	0.00e+00	1501.00
IUUC-Ont-071945	Oreochromis niloticus	79.56	0.00e+00	1394.00
IUUC-Oan-073384	Ornithorhynchus anatinus	84.55	0.00e+00	1198.00
IUUC-Ola-087499	Oryzias latipes	72.96	0.00e+00	1048.00
IUUC-Oga-088444	Otolemur garnettii	89.22	0.00e+00	1292.00
IUUC-Oar-089576	Ovis aries	85.30	0.00e+00	1199.00
IUUC-Ptr-090507	Pan troglodytes	96.32	0.00e+00	1645.00
IUUC-Pan-092325	Papio anubis	93.30	0.00e+00	1592.00
IUUC-Psi-094021	Pelodiscus sinensis	85.70	0.00e+00	1498.00
IUUC-Pma-094372	Petromyzon marinus	51.26	0.00e+00	685.00
IUUC-Pfo-096732	Poecilia formosa	80.58	0.00e+00	1431.00
IUUC-Pab-098426	Pongo abelii	79.02	0.00e+00	1170.00
IUUC-Pca-100295	Procavia capensis	90.55	0.00e+00	1482.00
IUUC-Rno-105332	Rattus norvegicus	91.96	0.00e+00	1549.00
IUUC-Sha-106529	Sarcophilus harrisii	90.79	0.00e+00	1285.00
IUUC-Ssc-116176	Sus scrofa	90.66	0.00e+00	1442.00
IUUC-Tgu-116917	Taeniopygia guttata	87.82	0.00e+00	1397.00
IUUC-Tru-118398	Takifugu rubripes	76.46	0.00e+00	971.00
IUUC-Tni-120819	Tetraodon nigroviridis	76.95	0.00e+00	1180.00
IUUC-Xtr-132747	Xenopus tropicalis	76.70	0.00e+00	1338.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence