iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088237

Ensembl Protein ID

ENSOGAP00000020881.1

UniProt Accession

H0XXN8; H0XXN8_OTOGA

Genbank Protein ID

ENSOGAP00000020881

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03106052

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000030741.1	ENSOGAT00000028890.1	ENSOGAP00000020881.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.80e-17	60.4	166	201

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           H++ vtc+a     dt ++s+s D+ i +WD r+ +
   Q: 166  HAGQVTCVAAsphKDTVFLSCSEDNRILLWDNRCPK 201
           99******988765599**************88765 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MRKETPQPLM PPAAREWNLP PNAPACMERQ LEASRYRSDG ALLLGASSLS GRCWAGSLWF 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG DRGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTGCTGCG GGATCTGAGT CTCCTGCAGG CTTTCAATCT GGTTTTAGGT GGAAGTTGGA 60
ACCGCGGAAA TGCGGAAGGA AACTCCGCAG CCCCTAATGC CCCCGGCAGC CCGCGAGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	91.55	5.00e-179	619.00
IUUC-Apl-003921	Anas platyrhynchos	61.05	2.00e-64	238.00
IUUC-Aca-004870	Anolis carolinensis	71.33	7.00e-121	426.00
IUUC-Ame-011872	Astyanax mexicanus	45.00	5.00e-36	143.00
IUUC-Bta-013325	Bos taurus	92.98	0.00e+00	630.00
IUUC-Cja-019059	Callithrix jacchus	93.27	0.00e+00	629.00
IUUC-Cfa-021036	Canis familiaris	92.44	4.00e-159	554.00
IUUC-Cpo-022369	Cavia porcellus	91.52	3.00e-180	624.00
IUUC-Csa-023585	Chlorocebus sabaeus	93.27	0.00e+00	631.00
IUUC-Cho-024470	Choloepus hoffmanni	83.82	3.00e-117	414.00
IUUC-Dno-029867	Dasypus novemcinctus	88.60	2.00e-176	610.00
IUUC-Dor-030834	Dipodomys ordii	65.01	4.00e-116	410.00
IUUC-Ete-032245	Echinops telfairi	83.16	5.00e-140	490.00
IUUC-Eca-033360	Equus caballus	92.11	1.00e-174	605.00
IUUC-Eeu-035353	Erinaceus europaeus	89.47	4.00e-177	613.00
IUUC-Fca-036277	Felis catus	93.57	0.00e+00	631.00
IUUC-Fal-037383	Ficedula albicollis	66.93	6.00e-101	359.00
IUUC-Gmo-038575	Gadus morhua	52.25	8.00e-96	343.00
IUUC-Gga-040658	Gallus gallus	68.71	5.00e-127	447.00
IUUC-Gac-041463	Gasterosteus aculeatus	51.10	1.00e-82	299.00
IUUC-Ggo-045120	Gorilla gorilla	91.81	2.00e-180	624.00
IUUC-Hsa-046247	Homo sapiens	92.11	0.00e+00	626.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	92.69	5.00e-177	613.00
IUUC-Lch-049741	Latimeria chalumnae	64.24	1.00e-109	389.00
IUUC-Loc-052695	Lepisosteus oculatus	57.02	8.00e-103	366.00
IUUC-Laf-054535	Loxodonta africana	89.08	1.00e-175	608.00
IUUC-Mcc-054699	Macaca mulatta	93.27	0.00e+00	631.00
IUUC-Meu-056053	Macropus eugenii	76.63	2.00e-139	488.00
IUUC-Mga-059672	Meleagris gallopavo	62.89	2.00e-69	254.00
IUUC-Mmr-060963	Microcebus murinus	95.03	0.00e+00	644.00
IUUC-Mdo-062694	Monodelphis domestica	73.18	5.00e-133	467.00
IUUC-Mmu-064031	Mus musculus	89.47	5.00e-177	613.00
IUUC-Mpu-066408	Mustela putorius furo	92.40	0.00e+00	629.00
IUUC-Mlu-068184	Myotis lucifugus	89.50	1.00e-174	605.00
IUUC-Nle-069251	Nomascus leucogenys	92.98	0.00e+00	630.00
IUUC-Opr-071156	Ochotona princeps	84.50	1.00e-164	572.00
IUUC-Ont-072683	Oreochromis niloticus	55.45	1.00e-94	339.00
IUUC-Oan-073042	Ornithorhynchus anatinus	76.04	6.00e-127	446.00
IUUC-Ocu-074843	Oryctolagus cuniculus	93.29	5.00e-178	616.00
IUUC-Ola-086929	Oryzias latipes	51.39	1.00e-85	309.00
IUUC-Oar-089312	Ovis aries	93.35	2.00e-167	581.00
IUUC-Ptr-091625	Pan troglodytes	92.11	1.00e-180	625.00
IUUC-Pan-091902	Papio anubis	92.64	2.00e-171	594.00
IUUC-Psi-094035	Pelodiscus sinensis	70.51	2.00e-124	438.00
IUUC-Pma-094565	Petromyzon marinus	63.54	2.00e-57	214.00
IUUC-Pfo-097070	Poecilia formosa	52.88	5.00e-90	324.00
IUUC-Pab-098007	Pongo abelii	92.69	0.00e+00	629.00
IUUC-Pca-100513	Procavia capensis	72.18	6.00e-101	359.00
IUUC-Pva-102821	Pteropus vampyrus	87.13	2.00e-165	575.00
IUUC-Rno-105836	Rattus norvegicus	90.23	2.00e-180	624.00
IUUC-Sha-106847	Sarcophilus harrisii	69.88	2.00e-90	325.00
IUUC-Sar-113451	Sorex araneus	85.13	4.00e-168	583.00
IUUC-Ssc-115978	Sus scrofa	91.81	6.00e-176	609.00
IUUC-Tgu-116745	Taeniopygia guttata	67.54	7.00e-93	332.00
IUUC-Tru-117945	Takifugu rubripes	52.48	1.00e-79	289.00
IUUC-Tsy-119059	Tarsius syrichta	90.40	1.00e-91	328.00
IUUC-Tni-120414	Tetraodon nigroviridis	53.25	4.00e-92	331.00
IUUC-Tbe-127559	Tupaia belangeri	95.32	0.00e+00	644.00
IUUC-Ttr-128505	Tursiops truncatus	90.64	1.00e-175	608.00
IUUC-Vpa-130350	Vicugna pacos	94.51	3.00e-101	360.00
IUUC-Xtr-132939	Xenopus tropicalis	59.94	9.00e-110	389.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence