iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003908

Ensembl Protein ID

ENSAPLP00000002866.1

UniProt Accession

S4SLT1; S4SLT1_ANAPL

Genbank Protein ID

AFP44845.1; ALE99279.1

Protein Name

Nucleotide-binding oligomerization domain containing 1; Nucleotide-binding oligomerization domain-containing protein 1

Genbank Nucleotide ID

ADON01121496; KR091070

Gene Name

NOD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000003385.1	ENSAPLT00000003460.1	ENSAPLP00000002866.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	62.37	0.00e+00	1148.00	IUUC-Hsa-046886

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MEGQLCANLE ISLEKPPGAS PPSCIALLKI YRELLVSKIR NTQCLIDNLL YNEYFSTEDA 60
EIVVQFPTQA DKVRKILDLV QSKGEEVSEY FIRVLQKVTD AYYELQPWLD EIAYEPSENI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGGCC AACTTTGTGC TAACTTGGAG ATTTCCTTGG AAAAACCTCC AGGAGCAAGC 60
CCGCCGTCCT GCATTGCTTT GCTGAAGATC TACCGAGAGC TTCTGGTCAG TAAGATCCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007109--Brix
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase

PROSITE

PS50209--CARD
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0071225--P:cellular response to muramyl dipeptide
GO:0050830--P:defense response to Gram-positive bacterium
GO:0016045--P:detection of bacterium
GO:0042228--P:interleukin-8 biosynthetic process
GO:0035556--P:intracellular signal transduction
GO:0002606--P:positive regulation of dendritic cell antigen processing and presentation
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032755--P:positive regulation of interleukin-6 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:1904417--P:positive regulation of xenophagy

KEGG

apla:101803391

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001299	Ailuropoda melanoleuca	62.02	0.00e+00	1043.00
IUUC-Aca-005144	Anolis carolinensis	72.90	0.00e+00	1364.00
IUUC-Ame-010829	Astyanax mexicanus	53.69	0.00e+00	966.00
IUUC-Bta-013358	Bos taurus	63.65	0.00e+00	1128.00
IUUC-Cja-019392	Callithrix jacchus	61.59	0.00e+00	1087.00
IUUC-Cfa-020776	Canis familiaris	63.89	0.00e+00	1117.00
IUUC-Cpo-021393	Cavia porcellus	59.98	0.00e+00	1065.00
IUUC-Csa-023872	Chlorocebus sabaeus	61.90	0.00e+00	1110.00
IUUC-Cho-024569	Choloepus hoffmanni	56.68	2.00e-123	436.00
IUUC-Dre-027478	Danio rerio	53.06	0.00e+00	949.00
IUUC-Dno-029231	Dasypus novemcinctus	64.04	0.00e+00	1160.00
IUUC-Dor-030251	Dipodomys ordii	44.99	3.00e-123	436.00
IUUC-Ete-032484	Echinops telfairi	55.47	5.00e-152	531.00
IUUC-Eca-033564	Equus caballus	64.13	0.00e+00	1149.00
IUUC-Eeu-034456	Erinaceus europaeus	52.42	1.00e-102	367.00
IUUC-Fca-036372	Felis catus	64.42	0.00e+00	1138.00
IUUC-Fal-037418	Ficedula albicollis	88.22	0.00e+00	1669.00
IUUC-Gmo-038740	Gadus morhua	53.03	0.00e+00	961.00
IUUC-Gga-040775	Gallus gallus	91.59	0.00e+00	1734.00
IUUC-Gac-041612	Gasterosteus aculeatus	53.82	0.00e+00	955.00
IUUC-Ggo-045161	Gorilla gorilla	60.63	0.00e+00	902.00
IUUC-Hsa-046886	Homo sapiens	62.00	0.00e+00	1107.00
IUUC-Itr-048414	Ictidomys tridecemlineatus	62.04	0.00e+00	1154.00
IUUC-Lch-049764	Latimeria chalumnae	63.18	0.00e+00	1084.00
IUUC-Loc-052143	Lepisosteus oculatus	58.32	0.00e+00	1086.00
IUUC-Laf-053503	Loxodonta africana	63.50	0.00e+00	1124.00
IUUC-Mcc-054992	Macaca mulatta	62.32	0.00e+00	1109.00
IUUC-Meu-056406	Macropus eugenii	55.37	0.00e+00	934.00
IUUC-Mga-059351	Meleagris gallopavo	90.46	0.00e+00	1705.00
IUUC-Mmr-061537	Microcebus murinus	62.51	0.00e+00	1062.00
IUUC-Mdo-061832	Monodelphis domestica	56.85	0.00e+00	947.00
IUUC-Mmu-064282	Mus musculus	60.40	0.00e+00	1119.00
IUUC-Mpu-066399	Mustela putorius furo	64.71	0.00e+00	1149.00
IUUC-Mlu-067265	Myotis lucifugus	62.88	0.00e+00	1093.00
IUUC-Nle-069078	Nomascus leucogenys	61.69	0.00e+00	1096.00
IUUC-Opr-070946	Ochotona princeps	55.94	0.00e+00	981.00
IUUC-Ont-071355	Oreochromis niloticus	53.18	0.00e+00	964.00
IUUC-Oan-072937	Ornithorhynchus anatinus	67.70	0.00e+00	1233.00
IUUC-Ocu-073815	Oryctolagus cuniculus	62.32	0.00e+00	1142.00
IUUC-Ola-087381	Oryzias latipes	52.67	0.00e+00	932.00
IUUC-Oga-088725	Otolemur garnettii	62.37	0.00e+00	1119.00
IUUC-Oar-090401	Ovis aries	63.02	0.00e+00	1145.00
IUUC-Ptr-090590	Pan troglodytes	61.90	0.00e+00	1104.00
IUUC-Pan-091765	Papio anubis	62.21	0.00e+00	1110.00
IUUC-Psi-093182	Pelodiscus sinensis	78.55	0.00e+00	1466.00
IUUC-Pma-094167	Petromyzon marinus	27.26	2.00e-53	203.00
IUUC-Ppa-095344	Physcomitrella patens	25.24	9.00e-04	38.90
IUUC-Pfo-097422	Poecilia formosa	51.77	0.00e+00	940.00
IUUC-Pab-098289	Pongo abelii	62.34	0.00e+00	1109.00
IUUC-Pca-100165	Procavia capensis	57.68	0.00e+00	780.00
IUUC-Pva-102943	Pteropus vampyrus	62.84	0.00e+00	1124.00
IUUC-Rno-104930	Rattus norvegicus	60.68	0.00e+00	1105.00
IUUC-Sce-106163	Saccharomyces cerevisiae	22.50	1.80e+00	28.90
IUUC-Sha-106800	Sarcophilus harrisii	47.80	0.00e+00	734.00
IUUC-Sar-113205	Sorex araneus	56.10	0.00e+00	766.00
IUUC-Ssc-115910	Sus scrofa	62.47	0.00e+00	976.00
IUUC-Tgu-117179	Taeniopygia guttata	89.38	0.00e+00	1682.00
IUUC-Tru-118220	Takifugu rubripes	50.37	0.00e+00	902.00
IUUC-Tsy-119418	Tarsius syrichta	59.95	0.00e+00	880.00
IUUC-Tni-120033	Tetraodon nigroviridis	55.60	4.00e-70	257.00
IUUC-Tbe-127308	Tupaia belangeri	67.57	1.00e-149	523.00
IUUC-Ttr-129233	Tursiops truncatus	64.21	0.00e+00	1130.00
IUUC-Vpa-130620	Vicugna pacos	52.92	6.00e-84	305.00
IUUC-Xtr-132075	Xenopus tropicalis	57.11	0.00e+00	1065.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence