iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106800

Ensembl Protein ID

ENSSHAP00000004513.1

UniProt Accession

G3VMV8; G3VMV8_SARHA

Genbank Protein ID

ENSSHAP00000004513

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01206154

Gene Name

NOD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000003969.1	ENSSHAT00000004559.1	ENSSHAP00000004513.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	50.21	0.00e+00	801.00	IUUC-Hsa-046886

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MDTQALPEAR AAPRDSRSCI RLLRVERERL VTHLHNVQCL LDNLLVNEYF SGEDAEIVGA 60
CPTLPDKVRK MLDLVQSKGE EVCEYLIYVL QQIPDAFVDL QPWLEEIRFS SSELVRGRTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACACCC AGGCCCTCCC CGAGGCGAGG GCGGCGCCCC GGGACTCCCG CTCGTGCATC 60
CGGCTGCTCC GGGTGGAGCG AGAGCGCCTG GTCACCCACC TCCACAACGT CCAGTGTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007109--Brix
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase

PROSITE

PS50209--CARD
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0071225--P:cellular response to muramyl dipeptide
GO:0050830--P:defense response to Gram-positive bacterium
GO:0016045--P:detection of bacterium
GO:0042228--P:interleukin-8 biosynthetic process
GO:0035556--P:intracellular signal transduction
GO:0002606--P:positive regulation of dendritic cell antigen processing and presentation
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032755--P:positive regulation of interleukin-6 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:1904417--P:positive regulation of xenophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001299	Ailuropoda melanoleuca	59.83	6.00e-167	581.00
IUUC-Apl-003908	Anas platyrhynchos	42.55	0.00e+00	648.00
IUUC-Aca-005144	Anolis carolinensis	42.89	0.00e+00	638.00
IUUC-Afl-008411	Aspergillus flavus	30.88	1.50e-01	28.90
IUUC-Ame-010829	Astyanax mexicanus	37.04	8.00e-152	531.00
IUUC-Bta-013358	Bos taurus	58.45	0.00e+00	647.00
IUUC-Cja-019392	Callithrix jacchus	47.62	0.00e+00	682.00
IUUC-Cfa-020776	Canis familiaris	48.26	0.00e+00	640.00
IUUC-Cpo-021393	Cavia porcellus	58.70	0.00e+00	645.00
IUUC-Csa-023872	Chlorocebus sabaeus	48.09	0.00e+00	682.00
IUUC-Cho-024569	Choloepus hoffmanni	52.43	2.00e-120	426.00
IUUC-Dre-027478	Danio rerio	36.45	1.00e-129	457.00
IUUC-Dno-029231	Dasypus novemcinctus	48.56	0.00e+00	686.00
IUUC-Dor-030251	Dipodomys ordii	49.80	5.00e-56	213.00
IUUC-Ete-032484	Echinops telfairi	56.40	4.00e-163	568.00
IUUC-Eca-033564	Equus caballus	48.96	0.00e+00	666.00
IUUC-Eeu-034456	Erinaceus europaeus	52.22	2.00e-101	363.00
IUUC-Fca-036372	Felis catus	47.87	0.00e+00	627.00
IUUC-Fal-037418	Ficedula albicollis	42.62	4.00e-174	605.00
IUUC-Gmo-038740	Gadus morhua	37.50	4.00e-141	495.00
IUUC-Gga-040775	Gallus gallus	44.16	0.00e+00	631.00
IUUC-Gac-041612	Gasterosteus aculeatus	37.54	4.00e-144	505.00
IUUC-Ggo-045161	Gorilla gorilla	48.28	0.00e+00	667.00
IUUC-Hsa-046886	Homo sapiens	46.92	0.00e+00	682.00
IUUC-Itr-048414	Ictidomys tridecemlineatus	47.86	0.00e+00	719.00
IUUC-Lch-049764	Latimeria chalumnae	38.62	4.00e-145	508.00
IUUC-Loc-052143	Lepisosteus oculatus	39.20	1.00e-161	563.00
IUUC-Laf-053503	Loxodonta africana	47.60	0.00e+00	759.00
IUUC-Mcc-054992	Macaca mulatta	48.20	0.00e+00	683.00
IUUC-Meu-056406	Macropus eugenii	76.90	0.00e+00	901.00
IUUC-Mga-059351	Meleagris gallopavo	41.97	0.00e+00	677.00
IUUC-Mmr-061537	Microcebus murinus	48.43	0.00e+00	632.00
IUUC-Mdo-061832	Monodelphis domestica	50.06	1.00e-174	607.00
IUUC-Mmu-064282	Mus musculus	47.30	0.00e+00	651.00
IUUC-Mpu-066399	Mustela putorius furo	47.45	0.00e+00	645.00
IUUC-Mlu-067265	Myotis lucifugus	48.82	0.00e+00	670.00
IUUC-Nle-069078	Nomascus leucogenys	48.10	0.00e+00	678.00
IUUC-Opr-070946	Ochotona princeps	50.75	1.00e-141	497.00
IUUC-Ont-071355	Oreochromis niloticus	38.43	9.00e-146	511.00
IUUC-Oan-072937	Ornithorhynchus anatinus	61.86	0.00e+00	696.00
IUUC-Ocu-073815	Oryctolagus cuniculus	48.51	0.00e+00	707.00
IUUC-Ola-087381	Oryzias latipes	37.70	5.00e-145	508.00
IUUC-Oga-088725	Otolemur garnettii	48.44	0.00e+00	695.00
IUUC-Oar-090401	Ovis aries	57.60	0.00e+00	630.00
IUUC-Ptr-090590	Pan troglodytes	46.70	0.00e+00	679.00
IUUC-Pan-091765	Papio anubis	48.32	0.00e+00	685.00
IUUC-Psi-093182	Pelodiscus sinensis	44.87	7.00e-179	620.00
IUUC-Pma-094167	Petromyzon marinus	27.39	1.00e-30	127.00
IUUC-Ppa-095344	Physcomitrella patens	26.60	3.00e-03	37.40
IUUC-Pfo-097422	Poecilia formosa	36.87	2.00e-144	506.00
IUUC-Pab-098289	Pongo abelii	47.97	0.00e+00	680.00
IUUC-Pca-100165	Procavia capensis	38.69	2.00e-110	393.00
IUUC-Pva-102943	Pteropus vampyrus	48.84	0.00e+00	706.00
IUUC-Rno-104930	Rattus norvegicus	59.26	0.00e+00	650.00
IUUC-Sar-113205	Sorex araneus	54.07	4.00e-164	572.00
IUUC-Ssc-115910	Sus scrofa	49.70	0.00e+00	685.00
IUUC-Tgu-117179	Taeniopygia guttata	43.33	8.00e-167	580.00
IUUC-Tru-118220	Takifugu rubripes	37.81	3.00e-139	489.00
IUUC-Tsy-119418	Tarsius syrichta	59.36	8.00e-125	441.00
IUUC-Tni-120033	Tetraodon nigroviridis	44.04	5.00e-54	204.00
IUUC-Tbe-127308	Tupaia belangeri	82.71	2.00e-123	436.00
IUUC-Ttr-129233	Tursiops truncatus	46.81	0.00e+00	697.00
IUUC-Vpa-130620	Vicugna pacos	61.80	4.00e-80	292.00
IUUC-Xtr-132075	Xenopus tropicalis	37.51	1.00e-150	526.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence