iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003607

Ensembl Protein ID

ENSAPLP00000011852.1

UniProt Accession

U3IX76; U3IX76_ANAPL

Genbank Protein ID

ENSAPLP00000011852

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01017323

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000012088.1	ENSAPLT00000012584.1	ENSAPLP00000011852.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	82.22	2.00e-95	345.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MVTHSKFPTA GMSRPLDTSL RLKTFSSKSE YQLVVNTVRK LQESGFYWST VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTESGT KNLRIQCEGG SFSLQSDPRS SQPVPRFDCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCACCC ACAGCAAGTT CCCCACCGCC GGGATGAGCC GCCCCCTCGA CACCAGCCTG 60
CGCCTGAAGA CGTTCAGCTC CAAGAGCGAG TACCAGCTGG TGGTCAACAC CGTGCGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	80.44	1.00e-99	355.00
IUUC-Aca-005063	Anolis carolinensis	86.73	1.00e-102	365.00
IUUC-Ath-006990	Arabidopsis thaliana	31.76	3.40e-02	33.90
IUUC-Ame-010859	Astyanax mexicanus	56.89	9.00e-68	249.00
IUUC-Bta-012817	Bos taurus	80.79	1.00e-104	372.00
IUUC-Cja-019605	Callithrix jacchus	81.33	2.00e-103	367.00
IUUC-Cfa-021231	Canis familiaris	81.78	2.00e-101	360.00
IUUC-Cpo-022003	Cavia porcellus	80.70	5.00e-101	359.00
IUUC-Csa-023511	Chlorocebus sabaeus	82.22	1.00e-102	364.00
IUUC-Dre-028536	Danio rerio	63.81	5.00e-75	273.00
IUUC-Dno-029003	Dasypus novemcinctus	81.25	2.00e-102	363.00
IUUC-Eca-034205	Equus caballus	70.39	5.00e-64	236.00
IUUC-Fca-036317	Felis catus	80.72	2.00e-99	354.00
IUUC-Gmo-038777	Gadus morhua	62.04	8.00e-35	138.00
IUUC-Gga-041258	Gallus gallus	94.74	2.00e-104	370.00
IUUC-Gac-041837	Gasterosteus aculeatus	62.44	1.00e-68	252.00
IUUC-Ggo-045620	Gorilla gorilla	82.22	1.00e-102	364.00
IUUC-Hsa-046909	Homo sapiens	82.22	1.00e-102	364.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	79.06	4.00e-102	363.00
IUUC-Lch-049510	Latimeria chalumnae	73.33	6.00e-84	302.00
IUUC-Loc-052863	Lepisosteus oculatus	70.67	2.00e-82	297.00
IUUC-Laf-054136	Loxodonta africana	80.26	4.00e-102	363.00
IUUC-Mcc-055383	Macaca mulatta	82.22	1.00e-102	364.00
IUUC-Meu-056153	Macropus eugenii	81.42	9.00e-105	372.00
IUUC-Mmr-061185	Microcebus murinus	80.97	9.00e-101	358.00
IUUC-Mdo-061819	Monodelphis domestica	81.78	3.00e-104	370.00
IUUC-Mmu-064231	Mus musculus	82.22	1.00e-103	368.00
IUUC-Mpu-066691	Mustela putorius furo	81.78	2.00e-101	360.00
IUUC-Mlu-067673	Myotis lucifugus	80.53	2.00e-103	367.00
IUUC-Ont-072406	Oreochromis niloticus	63.41	1.00e-74	271.00
IUUC-Oan-073249	Ornithorhynchus anatinus	83.08	3.00e-94	336.00
IUUC-Ocu-074935	Oryctolagus cuniculus	77.94	3.00e-28	115.00
IUUC-Ola-087373	Oryzias latipes	51.91	5.00e-50	189.00
IUUC-Oga-088041	Otolemur garnettii	82.14	2.00e-102	363.00
IUUC-Oar-089646	Ovis aries	78.60	5.00e-98	349.00
IUUC-Ptr-091502	Pan troglodytes	82.22	1.00e-102	364.00
IUUC-Pan-091934	Papio anubis	82.22	1.00e-102	364.00
IUUC-Pfo-096412	Poecilia formosa	47.32	2.00e-50	191.00
IUUC-Pab-098554	Pongo abelii	82.22	1.00e-102	364.00
IUUC-Rno-105874	Rattus norvegicus	81.94	8.00e-104	369.00
IUUC-Sha-107151	Sarcophilus harrisii	80.70	2.00e-104	370.00
IUUC-Ssc-115722	Sus scrofa	73.10	1.00e-61	227.00
IUUC-Tgu-117151	Taeniopygia guttata	94.26	1.00e-103	367.00
IUUC-Tru-118428	Takifugu rubripes	62.93	2.00e-72	264.00
IUUC-Tni-120590	Tetraodon nigroviridis	63.41	9.00e-72	262.00
IUUC-Ttr-129065	Tursiops truncatus	80.35	4.00e-102	363.00
IUUC-Xtr-132167	Xenopus tropicalis	75.12	2.00e-86	311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence