iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-024026

Ensembl Protein ID

ENSCSAP00000001824.1

UniProt Accession

A0A0D9QZN5; A0A0D9QZN5_CHLSB

Genbank Protein ID

ENSCSAP00000001824

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01042606

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000005515.1	ENSCSAT00000003547.1	ENSCSAP00000001824.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	5.00e-06	26.6	126	226
E3 adaptor/Cullin RING/DCX/DWD	3.30e-16	58.7	356	389

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 47   rpraqrrasrrtprqpprgpsa.aakpkaglrseaaaapapapaptptpeegpdaglldrlpeeilveilklldkeellraarvcrrwq 134
           r ra+rr   r  r   +g  a a  p +gl   a a      a   +    +    l rlpee+l+ i+++ld + l+r+a+vcr ++
   Q: 126  RVRARRREGARPGRAQRQGGQAwADIPGTGLAMAAEAGEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLR 214
           889****99999998777776625679****9998888888777777777767777899****************************** PP
   S: 135  elasqkalwktv 146
           +++s + lw+++
   Q: 215  RFTSCDLLWRRI 226
           ***999999976 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H+ +v+c++  ++++vsGs+D t kvW l +g+l
   Q: 356  HEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL 389
           99*******9449***************999875 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MGSQGRSGPP GNGGPGEGEG GEARKLQEGR VARGKRRKGK GKGKGKARAG QGGRGSGAEG 60
KPGPQTAKEA AGPGAEAGAR ACPREEAEGG GSVEEGARGI IKGDEGSAGA GKEAQGREYR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTCGGACT GGCCTCCGCG TCGGGCCGGC CCCGCCGCCG CTCATGGGCA GCCAGGGCCG 60
CTCGGGGCCC CCCGGCAACG GCGGGCCCGG CGAGGGCGAG GGCGGAGAGG CGAGGAAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	97.59	0.00e+00	763.00
IUUC-Apl-003837	Anas platyrhynchos	71.74	4.00e-142	497.00
IUUC-Aca-004776	Anolis carolinensis	67.12	2.00e-139	488.00
IUUC-Ame-010651	Astyanax mexicanus	62.11	2.00e-114	405.00
IUUC-Bta-013495	Bos taurus	95.99	0.00e+00	721.00
IUUC-Cja-018901	Callithrix jacchus	99.19	0.00e+00	736.00
IUUC-Cfa-021251	Canis familiaris	96.52	0.00e+00	754.00
IUUC-Cpo-021750	Cavia porcellus	94.46	0.00e+00	652.00
IUUC-Cho-024496	Choloepus hoffmanni	75.61	3.00e-158	551.00
IUUC-Cin-025142	Ciona intestinalis	31.10	1.00e-24	106.00
IUUC-Csv-025883	Ciona savignyi	36.87	2.00e-65	243.00
IUUC-Dre-027447	Danio rerio	59.11	5.00e-133	467.00
IUUC-Dno-029572	Dasypus novemcinctus	81.52	5.00e-173	600.00
IUUC-Dor-030982	Dipodomys ordii	88.89	0.00e+00	676.00
IUUC-Dme-031804	Drosophila melanogaster	22.70	2.00e-10	59.70
IUUC-Ete-032917	Echinops telfairi	95.69	0.00e+00	657.00
IUUC-Eca-033969	Equus caballus	97.70	0.00e+00	730.00
IUUC-Eeu-034850	Erinaceus europaeus	85.09	0.00e+00	649.00
IUUC-Fca-036182	Felis catus	92.25	0.00e+00	691.00
IUUC-Fal-037391	Ficedula albicollis	68.27	7.00e-148	516.00
IUUC-Gmo-038632	Gadus morhua	57.03	7.00e-128	450.00
IUUC-Gga-040783	Gallus gallus	72.78	8.00e-161	559.00
IUUC-Gac-042314	Gasterosteus aculeatus	57.11	4.00e-113	400.00
IUUC-Ggo-044739	Gorilla gorilla	98.92	0.00e+00	771.00
IUUC-Hsa-046705	Homo sapiens	98.92	0.00e+00	735.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	98.62	3.00e-174	603.00
IUUC-Loc-052397	Lepisosteus oculatus	65.45	9.00e-140	489.00
IUUC-Laf-054544	Loxodonta africana	94.35	0.00e+00	659.00
IUUC-Meu-056363	Macropus eugenii	58.77	7.00e-102	363.00
IUUC-Mga-059275	Meleagris gallopavo	73.04	4.00e-144	503.00
IUUC-Mmr-060906	Microcebus murinus	98.92	0.00e+00	763.00
IUUC-Mdo-062400	Monodelphis domestica	77.27	3.00e-175	607.00
IUUC-Mmu-063556	Mus musculus	93.22	0.00e+00	724.00
IUUC-Mpu-066500	Mustela putorius furo	97.33	0.00e+00	760.00
IUUC-Mlu-068074	Myotis lucifugus	97.23	0.00e+00	664.00
IUUC-Nle-069601	Nomascus leucogenys	99.19	0.00e+00	773.00
IUUC-Opr-070904	Ochotona princeps	88.26	1.00e-147	515.00
IUUC-Ont-072679	Oreochromis niloticus	56.01	8.00e-122	430.00
IUUC-Oan-073434	Ornithorhynchus anatinus	72.43	5.00e-84	303.00
IUUC-Ocu-074649	Oryctolagus cuniculus	95.93	0.00e+00	735.00
IUUC-Ola-087336	Oryzias latipes	49.48	4.00e-104	371.00
IUUC-Oga-088590	Otolemur garnettii	95.39	0.00e+00	712.00
IUUC-Oar-090178	Ovis aries	93.33	0.00e+00	672.00
IUUC-Pan-092881	Papio anubis	99.73	0.00e+00	775.00
IUUC-Pfo-096176	Poecilia formosa	55.47	3.00e-113	402.00
IUUC-Pab-098285	Pongo abelii	99.19	0.00e+00	766.00
IUUC-Pca-100888	Procavia capensis	90.91	0.00e+00	695.00
IUUC-Pva-102184	Pteropus vampyrus	82.38	5.00e-177	613.00
IUUC-Rno-105668	Rattus norvegicus	94.31	0.00e+00	732.00
IUUC-Sha-106629	Sarcophilus harrisii	77.02	8.00e-154	535.00
IUUC-Ssc-116183	Sus scrofa	98.13	0.00e+00	773.00
IUUC-Tgu-116630	Taeniopygia guttata	71.47	1.00e-167	582.00
IUUC-Tru-118761	Takifugu rubripes	52.63	6.00e-117	413.00
IUUC-Tni-120651	Tetraodon nigroviridis	52.48	1.00e-59	222.00
IUUC-Ttr-128582	Tursiops truncatus	95.19	0.00e+00	711.00
IUUC-Vpa-130431	Vicugna pacos	76.19	3.00e-98	351.00
IUUC-Xtr-132655	Xenopus tropicalis	66.67	2.00e-149	521.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence