iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033785

Ensembl Protein ID

ENSECAP00000016144.1

UniProt Accession

F7A5I4; F7A5I4_HORSE

Protein Name

Uncharacterized protein

Gene Name

EML2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000018032.1	ENSECAT00000019704.1	ENSECAP00000016144.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-17	60.7	452	481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtcla.fsd.tllvsGsdDgtikvWD 29
           H ++v++l+ + d tl++ G++D  + +W 
   Q: 452  HDGGVFGLCaLRDgTLVSGGGRDRRVVLWG 481
           999****97367746655588********6 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAERGPAFCG LYDTSSLLQY CNDDNLSGTS GMEVDDRVSA LEQRLQLQED ELAVLKAALA 60
DALRRLRACE EQGAALRARG TPKGRAPPRL GTTASGLPTR TPLNGSGPPR RVGGYATSPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC GCGGCCCGGC CTTCTGCGGC CTCTACGACA CGTCCTCGCT GCTTCAATAC 60
TGCAACGGTG AGACCCCCTC CTCAGTTCTG ACCCCGGCCC GCTCAGGGCT GGACCCATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0072686--C:mitotic spindle
GO:0008017--F:microtubule binding
GO:0031115--P:negative regulation of microtubule polymerization
GO:0010968--P:regulation of microtubule nucleation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	95.36	0.00e+00	1459.00
IUUC-Aca-005316	Anolis carolinensis	75.06	0.00e+00	1163.00
IUUC-Bta-013267	Bos taurus	94.13	0.00e+00	1485.00
IUUC-Cja-019146	Callithrix jacchus	89.58	0.00e+00	1203.00
IUUC-Cfa-020267	Canis familiaris	95.96	0.00e+00	1511.00
IUUC-Dre-028734	Danio rerio	66.09	0.00e+00	1079.00
IUUC-Dno-028961	Dasypus novemcinctus	93.46	0.00e+00	1430.00
IUUC-Eeu-035302	Erinaceus europaeus	94.02	0.00e+00	719.00
IUUC-Fca-036170	Felis catus	92.79	0.00e+00	1423.00
IUUC-Gac-042643	Gasterosteus aculeatus	63.60	0.00e+00	1000.00
IUUC-Ggo-044669	Gorilla gorilla	92.03	0.00e+00	1398.00
IUUC-Hsa-046141	Homo sapiens	95.31	0.00e+00	1496.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	93.65	0.00e+00	1471.00
IUUC-Loc-052518	Lepisosteus oculatus	67.86	0.00e+00	1065.00
IUUC-Laf-054137	Loxodonta africana	90.12	0.00e+00	1171.00
IUUC-Mcc-055780	Macaca mulatta	95.85	0.00e+00	1190.00
IUUC-Meu-056664	Macropus eugenii	83.83	0.00e+00	1125.00
IUUC-Mmr-060853	Microcebus murinus	94.44	0.00e+00	1483.00
IUUC-Mdo-062224	Monodelphis domestica	84.29	0.00e+00	1156.00
IUUC-Mmu-063860	Mus musculus	94.68	0.00e+00	1490.00
IUUC-Mpu-066043	Mustela putorius furo	96.17	0.00e+00	1501.00
IUUC-Mlu-067125	Myotis lucifugus	74.57	0.00e+00	1050.00
IUUC-Nle-069618	Nomascus leucogenys	86.67	0.00e+00	1276.00
IUUC-Opr-070228	Ochotona princeps	86.31	0.00e+00	1129.00
IUUC-Ont-071258	Oreochromis niloticus	63.74	0.00e+00	1019.00
IUUC-Ocu-074087	Oryctolagus cuniculus	81.50	0.00e+00	854.00
IUUC-Oga-088048	Otolemur garnettii	91.31	0.00e+00	1424.00
IUUC-Oar-089907	Ovis aries	93.94	0.00e+00	1224.00
IUUC-Pan-092082	Papio anubis	95.35	0.00e+00	1503.00
IUUC-Pab-097619	Pongo abelii	94.91	0.00e+00	1272.00
IUUC-Pca-101070	Procavia capensis	84.14	0.00e+00	1083.00
IUUC-Pva-102957	Pteropus vampyrus	90.81	0.00e+00	1187.00
IUUC-Rno-105074	Rattus norvegicus	94.08	0.00e+00	1237.00
IUUC-Sha-106692	Sarcophilus harrisii	82.48	0.00e+00	1214.00
IUUC-Tru-117809	Takifugu rubripes	61.60	0.00e+00	1057.00
IUUC-Tni-120815	Tetraodon nigroviridis	62.29	0.00e+00	1062.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence