iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005088

UUCD1 version

UUC-AnC-01021

Ensembl Protein ID

ENSACAP00000012151.3

UniProt Accession

G1KM85; G1KM85_ANOCA

Protein Name

Uncharacterized protein

Gene Name

usp18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000012304.3	ENSACAT00000012397.3	ENSACAP00000012151.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-54	185.0	62	378

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+g  C +NS+LQ+ ++ + ++  l +    k++ +  +e+k+++  ++  l+e++++sk+k+v p +l+++l+k  ++   +  
   Q: 62   VGLYNIGLNCCLNSLLQVFFMNRFFTMILRR---IKVPFDV-DEQKASVPYQMLLLLEQMQQSKQKSVHPMNLVQCLSKHDVK--LFVL 144
           6*****************9999888887777...5555443.5889********************************99877..7888 PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
            Da E++ +l + +++++                          + +   + +++ + ++lk++++c+ec  +++++++ + l+l++++
   Q: 145  YDAAELFLILWNLIKDQI--------------------------TSTDLAERLTHQYTIRLKEHLTCQECSYETKKDSNLIMLPLHLSD 207
           9*****************..........................566777889999********************************* PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
           +++ + ++l+d+L+ f++ e++ +e  + ce+c++k    + +k++ lP++L+lhLkRf+ s+e+++ +ki ++++fp++Ld s+ +t 
   Q: 208  SDSHAFKKLEDALHYFFASEQMMEESTFCCEQCNRKAPRLRGVKVTYLPQTLTLHLKRFT-SNERHRTRKIYNSLSFPQSLDFSQILTP 295
           ***********************************************************5.56679999***************66666 PP
   S: 268  ....peekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.......staYvlfYkrr 338
               p+ ++k++  Y+L+avv HsGs++ GHY+ayv + +++kW++f+Ds+V +v +++++ + g       +taY+l+Y+++
   Q: 296  eqycPDIQEKDDGLYDLFAVVPHSGSADFGHYCAYVWSlTEHKWYCFNDSSVCQVFWDDIKCTYGraslrwgETAYLLVYMKK 378
           445544445559************************9966777*******************888***************985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MGQNFAMQKR SKTLQLDEYQ TITAEDEKDG EEKEERKEDI MEKYNKKLKA ICGLADLRNG 60
AVGLYNIGLN CCLNSLLQVF FMNRFFTMIL RRIKVPFDVD EQKASVPYQM LLLLEQMQQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACGGGCTTC AGCGGGAAAT CAAAACTCAT CGCCGGCTGC TCGGTGCTGC CCTCTAAGGA 60
GAGGCGCCCA GCTGTCAAAA AGGGAGCGGA CCGCGCCGGG ATCGGAGGCT TCCCTGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0019785--F:ISG15-specific protease activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0035634--P:response to stilbenoid
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

acs:100554816

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	52.41	5.00e-91	327.00
IUUC-Apl-004006	Anas platyrhynchos	56.39	3.00e-103	368.00
IUUC-Ame-010606	Astyanax mexicanus	34.47	4.00e-45	174.00
IUUC-Bta-013036	Bos taurus	49.69	2.00e-89	322.00
IUUC-Cja-019052	Callithrix jacchus	51.54	2.00e-91	328.00
IUUC-Cfa-020554	Canis familiaris	55.28	5.00e-100	357.00
IUUC-Cpo-022421	Cavia porcellus	56.62	5.00e-103	367.00
IUUC-Csa-023737	Chlorocebus sabaeus	49.02	3.00e-55	207.00
IUUC-Cho-024807	Choloepus hoffmanni	43.94	3.00e-36	145.00
IUUC-Dre-027408	Danio rerio	33.33	4.00e-42	164.00
IUUC-Dno-029813	Dasypus novemcinctus	47.80	9.00e-72	263.00
IUUC-Dor-030532	Dipodomys ordii	52.63	2.00e-93	335.00
IUUC-Ete-032254	Echinops telfairi	50.46	8.00e-94	337.00
IUUC-Eca-033482	Equus caballus	54.72	2.00e-101	361.00
IUUC-Eeu-034451	Erinaceus europaeus	47.14	8.00e-54	202.00
IUUC-Fca-036313	Felis catus	54.35	2.00e-98	352.00
IUUC-Fal-037216	Ficedula albicollis	54.62	1.00e-113	402.00
IUUC-Gmo-038649	Gadus morhua	31.01	2.00e-38	152.00
IUUC-Gga-041082	Gallus gallus	56.53	3.00e-97	348.00
IUUC-Gac-042439	Gasterosteus aculeatus	34.17	2.00e-41	162.00
IUUC-Ggo-044957	Gorilla gorilla	52.79	5.00e-79	286.00
IUUC-Hsa-046381	Homo sapiens	55.38	1.00e-101	362.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	54.18	6.00e-98	350.00
IUUC-Loc-052688	Lepisosteus oculatus	32.09	2.00e-41	162.00
IUUC-Laf-054109	Loxodonta africana	55.49	1.00e-101	362.00
IUUC-Mcc-054814	Macaca mulatta	53.54	7.00e-100	357.00
IUUC-Meu-056253	Macropus eugenii	51.04	4.00e-74	270.00
IUUC-Mmr-061613	Microcebus murinus	51.93	2.00e-97	348.00
IUUC-Mdo-061890	Monodelphis domestica	48.96	5.00e-90	323.00
IUUC-Mmu-064329	Mus musculus	54.10	4.00e-95	340.00
IUUC-Mpu-066342	Mustela putorius furo	54.35	1.00e-98	352.00
IUUC-Mlu-067010	Myotis lucifugus	54.40	7.00e-99	353.00
IUUC-Nle-069148	Nomascus leucogenys	53.54	2.00e-99	355.00
IUUC-Opr-070988	Ochotona princeps	47.47	7.00e-44	171.00
IUUC-Ont-072039	Oreochromis niloticus	33.33	1.00e-41	163.00
IUUC-Oan-073740	Ornithorhynchus anatinus	44.04	3.00e-50	191.00
IUUC-Ocu-074498	Oryctolagus cuniculus	54.88	4.00e-94	338.00
IUUC-Ola-086753	Oryzias latipes	34.29	4.00e-44	171.00
IUUC-Oga-088497	Otolemur garnettii	50.92	1.00e-94	339.00
IUUC-Oar-089505	Ovis aries	51.26	4.00e-92	330.00
IUUC-Ptr-091656	Pan troglodytes	55.08	2.00e-101	362.00
IUUC-Pan-092498	Papio anubis	53.54	4.00e-100	357.00
IUUC-Psi-093409	Pelodiscus sinensis	60.92	2.00e-121	428.00
IUUC-Pfo-096507	Poecilia formosa	33.65	2.00e-42	166.00
IUUC-Pab-097828	Pongo abelii	54.01	6.00e-99	353.00
IUUC-Pca-100299	Procavia capensis	51.83	8.00e-54	204.00
IUUC-Pva-102972	Pteropus vampyrus	54.35	2.00e-99	355.00
IUUC-Rno-105738	Rattus norvegicus	52.27	2.00e-93	335.00
IUUC-Sha-107309	Sarcophilus harrisii	48.12	2.00e-85	308.00
IUUC-Sar-112983	Sorex araneus	52.28	1.00e-76	279.00
IUUC-Ssc-116049	Sus scrofa	53.94	4.00e-96	344.00
IUUC-Tgu-117115	Taeniopygia guttata	55.80	3.00e-101	361.00
IUUC-Tru-118022	Takifugu rubripes	31.88	7.00e-38	150.00
IUUC-Tni-120306	Tetraodon nigroviridis	31.37	2.00e-35	142.00
IUUC-Tbe-127768	Tupaia belangeri	45.99	1.00e-51	196.00
IUUC-Ttr-128686	Tursiops truncatus	52.63	7.00e-94	337.00
IUUC-Xtr-132032	Xenopus tropicalis	42.19	4.00e-71	261.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence