iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000012753.3	ENSXETT00000061722.1	ENSXETP00000061630.1
ENSXETG00000012753.3	ENSXETT00000027873.3	ENSXETP00000027873.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.60e-09	36.3	531	568

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C+iC++d++   +++pC H+fh +Cl kw       + +++CP+C
   Q: 531  CPICFQDMSG-AVITPCSHIFHGECLRKW------LYVQDTCPIC 568
           ********88.888***************......********** PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MSRLEEIANV VLRLPSVVVL DLLYRWDFQA FTELSRPTYE TNFFKSKYLW NIYYLAHVLC 60
AVLLLLPLRY LVSIYLYLLT ALLLYVGHQT TRDYIHQEMD SDFPGALFED QGALSRIITA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGATATGCA TGTAGTTACA CAGGGGTCGG GAAACTCCGG GGATCGGGGG CCTAGTAGCT 60
CTGGCTGCGA ATAGAAAGGA GCGATCCGGC TCTTTGCTTA CAAANNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005255	Anolis carolinensis	65.67	0.00e+00	668.00
IUUC-Acl-008354	Aspergillus clavatus	47.06	2.00e-06	48.10
IUUC-Afu-008993	Aspergillus fumigatus	44.12	2.00e-06	47.80
IUUC-Ani-009159	Aspergillus nidulans	44.12	3.00e-06	47.40
IUUC-Ate-010380	Aspergillus terreus	44.12	3.00e-06	47.40
IUUC-Bci-013813	Botrytis cinerea	32.00	1.00e-07	51.20
IUUC-Cgl-026705	Colletotrichum gloeosporioides	47.06	2.00e-06	47.80
IUUC-Dre-027727	Danio rerio	61.28	1.00e-180	625.00
IUUC-Gmo-038606	Gadus morhua	63.73	0.00e+00	667.00
IUUC-Gga-040190	Gallus gallus	68.16	0.00e+00	659.00
IUUC-Gac-042206	Gasterosteus aculeatus	62.67	0.00e+00	642.00
IUUC-Lch-050653	Latimeria chalumnae	61.83	3.00e-165	574.00
IUUC-Loc-051784	Lepisosteus oculatus	64.84	0.00e+00	661.00
IUUC-Nfi-068252	Neosartorya fischeri	44.12	2.00e-06	47.80
IUUC-Ont-071794	Oreochromis niloticus	63.08	0.00e+00	703.00
IUUC-Ola-087113	Oryzias latipes	62.78	0.00e+00	650.00
IUUC-Pfo-097150	Poecilia formosa	64.47	0.00e+00	692.00
IUUC-Tru-118554	Takifugu rubripes	63.26	0.00e+00	699.00
IUUC-Tni-120897	Tetraodon nigroviridis	63.64	0.00e+00	674.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence