iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023161

Ensembl Protein ID

ENSCSAP00000002612.1

UniProt Accession

A0A0D9R1X3; A0A0D9R1X3_CHLSB

Genbank Protein ID

ENSCSAP00000002612

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01146958

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000006321.1	ENSCSAT00000004358.1	ENSCSAP00000002612.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	98.35	0.00e+00	743.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MWATCCNWFC LDGQPEEVPP PQGARMQAYS NPGYSSFPSP TGLEPSCKSC GAHFASTARK 60
QTCLDCKKNF CMTCSSQVGN GPRLCLLCQR FRATAFQREE LMKMKVKDLR DYLSLHDIST 120

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Nucleotide Sequence
(Fasta)

AGGTGTATCT TAACTGACCT TTTCCCCTTT CCTCCCTTGC ACCAGATTTT ATCATGTGGG 60
CAACCTGCTG CAACTGGTTC TGCCTGGATG GACAGCCTGA AGAGGTCCCA CCACCCCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	90.08	0.00e+00	635.00
IUUC-Apl-004124	Anas platyrhynchos	65.48	5.00e-123	434.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	1.00e-08	55.50
IUUC-Ame-011616	Astyanax mexicanus	59.13	4.00e-104	370.00
IUUC-Bta-012374	Bos taurus	86.23	0.00e+00	635.00
IUUC-Cja-019780	Callithrix jacchus	95.33	0.00e+00	687.00
IUUC-Cfa-021252	Canis familiaris	92.01	0.00e+00	646.00
IUUC-Cpo-022047	Cavia porcellus	91.18	0.00e+00	661.00
IUUC-Cho-024316	Choloepus hoffmanni	91.09	8.00e-157	545.00
IUUC-Cne-026858	Cryptococcus neoformans	25.15	7.00e-07	48.50
IUUC-Dre-028596	Danio rerio	55.92	1.00e-109	389.00
IUUC-Dno-029333	Dasypus novemcinctus	91.74	0.00e+00	663.00
IUUC-Ete-033163	Echinops telfairi	83.20	1.00e-164	572.00
IUUC-Eca-033994	Equus caballus	92.01	0.00e+00	676.00
IUUC-Eeu-035162	Erinaceus europaeus	87.67	1.00e-133	468.00
IUUC-Fca-036418	Felis catus	90.91	0.00e+00	692.00
IUUC-Fal-037427	Ficedula albicollis	65.40	7.00e-132	463.00
IUUC-Gga-041053	Gallus gallus	67.49	2.00e-130	458.00
IUUC-Ggo-045436	Gorilla gorilla	98.35	0.00e+00	743.00
IUUC-Hsa-045798	Homo sapiens	98.35	0.00e+00	743.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	91.46	0.00e+00	646.00
IUUC-Lch-050639	Latimeria chalumnae	62.53	3.00e-126	444.00
IUUC-Laf-053355	Loxodonta africana	88.52	1.00e-178	619.00
IUUC-Mcc-055222	Macaca mulatta	98.90	0.00e+00	693.00
IUUC-Meu-056692	Macropus eugenii	77.96	4.00e-159	553.00
IUUC-Mga-059298	Meleagris gallopavo	66.39	4.00e-129	454.00
IUUC-Mmr-061792	Microcebus murinus	90.36	0.00e+00	642.00
IUUC-Mdo-062986	Monodelphis domestica	81.54	2.00e-170	591.00
IUUC-Mmu-063356	Mus musculus	88.43	0.00e+00	641.00
IUUC-Mpu-066273	Mustela putorius furo	91.18	0.00e+00	691.00
IUUC-Mlu-066953	Myotis lucifugus	90.91	0.00e+00	678.00
IUUC-Nle-070075	Nomascus leucogenys	98.07	0.00e+00	741.00
IUUC-Opr-070838	Ochotona princeps	89.53	0.00e+00	642.00
IUUC-Ont-071967	Oreochromis niloticus	74.83	1.00e-56	213.00
IUUC-Ocu-074807	Oryctolagus cuniculus	90.91	0.00e+00	680.00
IUUC-Obr-076159	Oryza brachyantha	41.07	4.00e-08	50.40
IUUC-Ola-086903	Oryzias latipes	68.21	9.00e-56	210.00
IUUC-Oga-088536	Otolemur garnettii	90.08	1.00e-179	622.00
IUUC-Oar-089838	Ovis aries	86.78	7.00e-180	622.00
IUUC-Ptr-090962	Pan troglodytes	98.07	0.00e+00	742.00
IUUC-Pan-092853	Papio anubis	98.62	0.00e+00	744.00
IUUC-Psi-093164	Pelodiscus sinensis	64.66	7.00e-125	440.00
IUUC-Pma-094104	Petromyzon marinus	44.65	6.00e-57	214.00
IUUC-Pno-094968	Phaeosphaeria nodorum	36.73	2.00e-08	56.20
IUUC-Pab-098304	Pongo abelii	98.90	0.00e+00	743.00
IUUC-Pca-100316	Procavia capensis	89.26	2.00e-177	614.00
IUUC-Ppe-101490	Prunus persica	37.80	1.00e-09	57.80
IUUC-Pva-102612	Pteropus vampyrus	77.41	1.00e-157	549.00
IUUC-Rno-105449	Rattus norvegicus	89.26	0.00e+00	640.00
IUUC-Sha-107578	Sarcophilus harrisii	80.44	1.00e-157	549.00
IUUC-Sar-113638	Sorex araneus	86.23	7.00e-176	609.00
IUUC-Ssc-116401	Sus scrofa	90.36	0.00e+00	684.00
IUUC-Tru-118765	Takifugu rubripes	49.59	3.00e-83	301.00
IUUC-Tsy-118850	Tarsius syrichta	89.77	1.00e-153	535.00
IUUC-Tbe-128086	Tupaia belangeri	84.57	0.00e+00	625.00
IUUC-Ttr-128249	Tursiops truncatus	69.70	2.00e-140	491.00
IUUC-Vpa-130816	Vicugna pacos	87.21	6.00e-41	160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence