iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041901

UUCD1 version

UUC-GaA-01223

Ensembl Protein ID

ENSGACP00000005471.1

UniProt Accession

G3NJG0; G3NJG0_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000004155.1	ENSGACT00000005487.1	ENSGACP00000005471.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-114	383.3	574	1306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeae 82
           tGl NlgNtC+mNSv+Q+Lsn++elr++++       ++ ++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a+
   Q: 574  TGLVNLGNTCFMNSVIQSLSNTRELRDYFHGvpadrGFEAEINCNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKAS 660
           7**********************************999************************************************* PP
   S: 83   efsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeed...kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssre 166
           +f+gy+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++  s+ea++++k++n+s+i+dlFqgq+ks+++c++c +vs ++
   Q: 661  QFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDgrlDEVVSEEAWQRHKMRNDSFIVDLFQGQFKSKLVCPTCSKVSITF 747
           ************************************99982223344555************************************* PP
   S: 167  epfldlslpvpgkeetkke.................................................................... 185
           +pfl+l++p+p+k++                                                                        
   Q: 748  DPFLYLPVPLPQKQKVLSVfyfakephkkpvkflvsvskensstaevldsisrnvrvrpenlrlaevgknrfqrlflpshsldmvss 834
           **************76444******************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 835  sdmlfcfevlskdmakervvllrvqqrlqvpnipiskcaacqkpspseedklkrctrcyrvgycnqrcvrrplanhkglcrpnaenv 921
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 922  glpflvsvpesrlsysritqllegysrfsvnvfqppfqsgraspetsqcrgdhppmaagppeglgpggeamaggntcavgdmespsl 1008
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1009 lpesqaecpqasalpsdsgfsapvsstsccsldphaeketscekavrpeaavtgyqhpsesasghasqfyialldsdnkeqrldere 1095
           *************************************************************************************** PP
   S: 186  ...................................................slqdcLesftkeeelegenkyycekckkkqeaekkl 221
                                                              +l++cL+ ftk+e l  e+++yc+kc++++ea+k+l
   Q: 1096 dlladlpedtklelvwknnerlkeyvlvsskeldydedpgslsetaraghfTLEQCLNLFTKPEVLAPEEAWYCPKCQQHREASKQL 1182
           *************************************************************************************** PP
   S: 222  klkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke..kkkYeLiavvvHsGslssGHYvayvknekgk 305
            l++lP+vLi++LkRfsf++  +++ kin+ v+fp + Ldls+fc+ ++++++   + +Y+L+av++H+G++ +GHY+ay++  ++k
   Q: 1183 LLWRLPNVLIIQLKRFSFRSFIWRD-KINDMVDFPVRnLDLSQFCIGQKDEEQMqqPPIYDLYAVINHYGGMIGGHYTAYARLPSDK 1268
           *********************8886.**********9********9865544323399************************94444 PP
   S: 306  ........WllfdDskVtevkeeevleetgstaYvlfYkrr 338
                   W lfdDs+Vt v+e++v++   + aYvlfY+rr
   Q: 1269 nsqrsdvgWRLFDDSTVTMVEESQVVT---RYAYVLFYRRR 1306
           44567788*******************...********996 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

SGLAAVLCLS FECPRRVQTS IIAKIAGPGR KRHTSDPDPS GGSDSGDGRP VSAKCPKMAS 60
SGAAGNGSVG RRGGAQQRGG GGGRDGADLP SSASKKKQKD RANQESREAK RAAAAAAEGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCGGCTTAG CTGCTGTCCT TTGTTTGTCA TTTGAATGTC CACGTTAGCA ACTTGCTGTT 60
GCTATGCTAA GGAAACGAGA CACCGCTCTC TGTCGGGATA GTTCGGCTAA CTGACATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND

PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2

Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001999	Ailuropoda melanoleuca	67.62	0.00e+00	1350.00
IUUC-Apl-003368	Anas platyrhynchos	66.95	0.00e+00	1364.00
IUUC-Aca-004267	Anolis carolinensis	69.71	0.00e+00	1357.00
IUUC-Ame-010970	Astyanax mexicanus	77.94	0.00e+00	1499.00
IUUC-Bta-012905	Bos taurus	67.73	0.00e+00	1328.00
IUUC-Cel-018257	Caenorhabditis elegans	42.86	6.00e-89	322.00
IUUC-Cja-018789	Callithrix jacchus	67.46	0.00e+00	1369.00
IUUC-Cfa-021004	Canis familiaris	69.03	0.00e+00	1331.00
IUUC-Cpo-021529	Cavia porcellus	66.97	0.00e+00	1325.00
IUUC-Csa-024035	Chlorocebus sabaeus	69.38	0.00e+00	1363.00
IUUC-Cho-025036	Choloepus hoffmanni	71.28	0.00e+00	631.00
IUUC-Cin-025451	Ciona intestinalis	40.47	2.00e-80	294.00
IUUC-Dre-028556	Danio rerio	73.54	0.00e+00	1516.00
IUUC-Dno-029240	Dasypus novemcinctus	65.55	0.00e+00	1269.00
IUUC-Dor-030495	Dipodomys ordii	64.62	0.00e+00	852.00
IUUC-Ete-032741	Echinops telfairi	68.77	0.00e+00	1330.00
IUUC-Eca-033661	Equus caballus	66.76	0.00e+00	1365.00
IUUC-Eeu-034648	Erinaceus europaeus	54.99	0.00e+00	679.00
IUUC-Fca-035646	Felis catus	69.36	0.00e+00	1333.00
IUUC-Fal-037094	Ficedula albicollis	64.41	0.00e+00	1428.00
IUUC-Gmo-038869	Gadus morhua	73.45	0.00e+00	1623.00
IUUC-Gga-041170	Gallus gallus	63.72	0.00e+00	1396.00
IUUC-Ggo-044708	Gorilla gorilla	67.65	0.00e+00	1374.00
IUUC-Hsa-046791	Homo sapiens	60.47	0.00e+00	1474.00
IUUC-Itr-048892	Ictidomys tridecemlineatus	66.91	0.00e+00	1304.00
IUUC-Lch-050456	Latimeria chalumnae	65.96	0.00e+00	1046.00
IUUC-Loc-052861	Lepisosteus oculatus	64.26	0.00e+00	1191.00
IUUC-Laf-053788	Loxodonta africana	68.02	0.00e+00	1365.00
IUUC-Mcc-055693	Macaca mulatta	69.18	0.00e+00	1355.00
IUUC-Meu-055921	Macropus eugenii	69.18	0.00e+00	1138.00
IUUC-Mga-059879	Meleagris gallopavo	66.10	0.00e+00	1391.00
IUUC-Mmr-060802	Microcebus murinus	64.85	0.00e+00	1368.00
IUUC-Mdo-061856	Monodelphis domestica	59.36	0.00e+00	1445.00
IUUC-Mmu-063874	Mus musculus	66.94	0.00e+00	1355.00
IUUC-Mpu-066166	Mustela putorius furo	68.73	0.00e+00	1324.00
IUUC-Nle-070161	Nomascus leucogenys	65.76	0.00e+00	1371.00
IUUC-Opr-071015	Ochotona princeps	59.96	0.00e+00	1400.00
IUUC-Ont-072308	Oreochromis niloticus	83.61	0.00e+00	1766.00
IUUC-Oan-072723	Ornithorhynchus anatinus	64.23	0.00e+00	1349.00
IUUC-Ocu-073938	Oryctolagus cuniculus	69.55	0.00e+00	1329.00
IUUC-Ola-086375	Oryzias latipes	83.57	0.00e+00	1624.00
IUUC-Oga-088297	Otolemur garnettii	66.31	0.00e+00	1353.00
IUUC-Oar-089675	Ovis aries	68.97	0.00e+00	1175.00
IUUC-Ptr-091621	Pan troglodytes	60.25	0.00e+00	1471.00
IUUC-Pan-092118	Papio anubis	69.38	0.00e+00	1362.00
IUUC-Pfo-097246	Poecilia formosa	81.50	0.00e+00	1654.00
IUUC-Pab-098551	Pongo abelii	60.10	0.00e+00	1454.00
IUUC-Pca-100158	Procavia capensis	64.36	0.00e+00	1293.00
IUUC-Pva-103160	Pteropus vampyrus	66.46	0.00e+00	1329.00
IUUC-Rno-105355	Rattus norvegicus	66.03	0.00e+00	1319.00
IUUC-Sha-107057	Sarcophilus harrisii	71.08	0.00e+00	1326.00
IUUC-Sar-113011	Sorex araneus	61.27	0.00e+00	998.00
IUUC-Ssc-115761	Sus scrofa	67.78	0.00e+00	1327.00
IUUC-Tgu-116956	Taeniopygia guttata	57.23	0.00e+00	770.00
IUUC-Tru-118739	Takifugu rubripes	81.31	0.00e+00	1653.00
IUUC-Tsy-118827	Tarsius syrichta	76.55	0.00e+00	673.00
IUUC-Tni-119921	Tetraodon nigroviridis	78.23	0.00e+00	1590.00
IUUC-Tbe-128017	Tupaia belangeri	64.63	0.00e+00	1306.00
IUUC-Ttr-128869	Tursiops truncatus	67.06	0.00e+00	1342.00
IUUC-Uma-129498	Ustilago maydis	29.79	2.00e-91	331.00
IUUC-Vpa-130427	Vicugna pacos	63.12	9.00e-171	594.00
IUUC-Xtr-132734	Xenopus tropicalis	69.28	0.00e+00	1332.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence