iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011915

Ensembl Protein ID

ENSAMXP00000008351.1

UniProt Accession

W5KL89; W5KL89_ASTMX

Genbank Protein ID

ENSAMXP00000008351

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01111531

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000008128.1	ENSAMXT00000008351.1	ENSAMXP00000008351.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-18	65.8	502	533
UBD/Beta-Prp	5.30e-44	150.8	389	593

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd..tllvsGsdDgtikvWDl 30
           gHtd v++la+s+  ++l+s+s Dgt+k+WD+
   Q: 502  GHTDAVWGLAYSGikNRLLSCSADGTVKLWDP 533
           8**********666689**************6 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdls...........tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirv 120
           ++  +l +h ++v+a+ f+p +++lvt+seD+t+k+w+l+           + ++++t+++h   vlsl++ +sg+   sG+ d+ti+ 
   Q: 389  NAKYTLRSHFDGVRALAFHPVEPVLVTVSEDHTLKLWNLQktvpakksasfDVEPIYTFRAHVGPVLSLAVTASGEQCFSGGIDSTIQW 477
           5556899********************************************************************************** PP
   S: 121  wdletgqclee..........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.ktgkllrtltgghtdsv.yslsfdsng.kelv 196
           w++++  +              l gh+++v+++++++ +n l s+s+D+tv+lWd  + + +l t+ ++ ++ + + ++f+     ++v
   Q: 478  WNIPSSNVDPYdtydpsvlagSLLGHTDAVWGLAYSGIKNRLLSCSADGTVKLWDPqEKMPCLCTFNSEREHGIpTAVDFNGCDpAYMV 566
           ***998877667899****************************************9888899****77666666255566654459999 PP
   S: 197  sgsldgtvklwdlqtgecvrtlnghtd 223
           +  + g+  ++dl+t++ v+++ +++d
   Q: 567  ASFNTGSAVIYDLETSQSVVEFSAQKD 593
           99999*****************99987 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MDEHPGGGGG AAAGGGMATA RQQQAPQQGN HNAVNPQIGP GGTAPAVQQQ DEMPRPQQYT 60
IPGILHYIQH EWARFEMERA HWEVERAELQ ARIAFLQGER KGQENLKNDL VRRIKMLEYA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGAAC ACCCCGGCGG AGGAGGAGGA GCAGCAGCAG GGGGAGGAAT GGCCACCGCC 60
AGACAGCAGC AAGCGCCGCA GCAGGGAAAC CATAACGCCG TTAATCCCCA GATCGGACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008170	Aspergillus clavatus	24.08	5.00e-19	90.10
IUUC-Ang-009868	Aspergillus niger	31.63	1.00e-15	79.00
IUUC-Dre-027566	Danio rerio	88.91	0.00e+00	1131.00
IUUC-Dme-032158	Drosophila melanogaster	48.99	1.00e-163	570.00
IUUC-Ete-032770	Echinops telfairi	73.29	0.00e+00	867.00
IUUC-Gmo-039653	Gadus morhua	69.90	0.00e+00	809.00
IUUC-Gac-042142	Gasterosteus aculeatus	74.49	0.00e+00	986.00
IUUC-Mga-059885	Meleagris gallopavo	84.27	1.00e-151	528.00
IUUC-Mpu-066348	Mustela putorius furo	79.88	0.00e+00	997.00
IUUC-Opr-070496	Ochotona princeps	83.58	4.00e-146	511.00
IUUC-Ont-072075	Oreochromis niloticus	77.99	0.00e+00	1004.00
IUUC-Pca-101047	Procavia capensis	75.38	2.00e-130	459.00
IUUC-Spo-108015	Schizosaccharomyces pombe	27.09	3.00e-16	80.10
IUUC-Sar-113296	Sorex araneus	71.88	0.00e+00	756.00
IUUC-Tru-118134	Takifugu rubripes	79.43	0.00e+00	977.00
IUUC-Tni-120791	Tetraodon nigroviridis	73.04	0.00e+00	941.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence