iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073977

UUCD1 version

UUC-OrC-00810

Ensembl Protein ID

ENSOCUP00000004286.3

UniProt Accession

G1SMW1; G1SMW1_RABIT

Protein Name

Uncharacterized protein

Gene Name

MEFV

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000004951.3	ENSOCUT00000004953.3	ENSOCUP00000004286.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	31.25	9.40e-01	30.80	IUUC-Sce-106201

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MEHFLCLFHY FTSSLSSPTL GAAWADGLFS WRGQAPAQTL LVSAMAKTPS DHLLNTLEEL 60
VPYDFEKFKF KLQNTSLEKE HSRIPRGQLQ MARPVRLATL LVTHYGEEHA VRLTLQVLRA 120

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Nucleotide Sequence
(Fasta)

ATGGAGCACT TCCTGTGCCT TTTCCATTAT TTCACAAGCA GCCTCTCCTC ACCCACCCTC 60
GGGGCTGCCT GGGCAGATGG CTTATTCTCC TGGAGAGGGC AGGCGCCGGC TCAGACTCTG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR004020--DAPIN
IPR011029--DEATH-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50188--B302_SPRY
PS50824--DAPIN
PS50119--ZF_BBOX

Pfam

PF13765--PRY
PF02758--PYRIN
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM01289--PYRIN
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005875--C:microtubule associated complex
GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0006954--P:inflammatory response
GO:1900016--P:negative regulation of cytokine production involved in inflammatory response
GO:0032691--P:negative regulation of interleukin-1 beta production
GO:0032695--P:negative regulation of interleukin-12 production
GO:0071641--P:negative regulation of macrophage inflammatory protein 1 alpha production
GO:1900226--P:negative regulation of NLRP3 inflammasome complex assembly
GO:0010508--P:positive regulation of autophagy
GO:2001056--P:positive regulation of cysteine-type endopeptidase activity
GO:0034341--P:response to interferon-gamma

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gmo-039308	Gadus morhua	30.40	2.00e-46	180.00
IUUC-Ont-071801	Oreochromis niloticus	29.00	1.00e-54	207.00
IUUC-Sce-106201	Saccharomyces cerevisiae	31.25	2.10e-01	30.80
IUUC-Tru-117950	Takifugu rubripes	30.30	5.00e-46	179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence