iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004861

UUCD1 version

UUC-AnC-00257

Ensembl Protein ID

ENSACAP00000010742.2

UniProt Accession

H9GH07; H9GH07_ANOCA

Protein Name

Uncharacterized protein

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000010868.3	ENSACAT00000010964.2	ENSACAP00000010742.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-42	141.6	235	276
UBD/Beta-Prp	2.40e-54	184.5	189	394

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllks 38
           gH ++v cl++    +++++vsG+ D++ +vWD+rtg +++s
   Q: 235  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRTGQCIQS 276
           8***********9644499********************996 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd++tgqc++  
   Q: 189  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRTGQCIQ-S 276
           567889999*********99***************************************9777************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g  v +l g
   Q: 277  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGARVSILFG 365
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++riW
   Q: 366  HENRVSTLRVSPDGTAFCSGSWDHTLRIW 394
           ***************************** PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MCDQTFLANV FGPCDKCSQN RALREIYHKN EKVSYCSLCV GMMATEGLKE NETLASLKNE 60
AESLKGKLEE ERAKLHDVEL HQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGACC AGACGTTTTT GGCCAATGTG TTTGGCCCAT GCGACAAATG TTCCCAAAAC 60
AGAGCCCTCC GGGAGATTTA CCACAAAAAT GAGAAAGTCA GCTACTGCTC ACTATGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	86.33	0.00e+00	726.00
IUUC-Apl-003399	Anas platyrhynchos	98.08	0.00e+00	646.00
IUUC-Ame-011851	Astyanax mexicanus	91.45	0.00e+00	683.00
IUUC-Bta-012438	Bos taurus	96.60	0.00e+00	718.00
IUUC-Cel-018408	Caenorhabditis elegans	65.99	8.00e-142	496.00
IUUC-Cja-019086	Callithrix jacchus	93.38	0.00e+00	775.00
IUUC-Cfa-021255	Canis familiaris	91.35	0.00e+00	724.00
IUUC-Cpo-021398	Cavia porcellus	90.91	0.00e+00	761.00
IUUC-Csa-023776	Chlorocebus sabaeus	97.17	0.00e+00	721.00
IUUC-Cin-025305	Ciona intestinalis	59.29	2.00e-133	468.00
IUUC-Csv-026058	Ciona savignyi	57.87	4.00e-130	457.00
IUUC-Dre-028432	Danio rerio	87.09	0.00e+00	695.00
IUUC-Dno-029958	Dasypus novemcinctus	78.97	1.00e-135	475.00
IUUC-Dor-031013	Dipodomys ordii	96.88	2.00e-151	528.00
IUUC-Dme-031889	Drosophila melanogaster	67.73	3.00e-148	517.00
IUUC-Eca-033977	Equus caballus	88.61	0.00e+00	737.00
IUUC-Eeu-035079	Erinaceus europaeus	91.84	0.00e+00	759.00
IUUC-Fca-035693	Felis catus	86.65	0.00e+00	728.00
IUUC-Fal-037345	Ficedula albicollis	98.30	0.00e+00	726.00
IUUC-Gmo-039222	Gadus morhua	89.69	0.00e+00	658.00
IUUC-Gga-040320	Gallus gallus	98.30	0.00e+00	726.00
IUUC-Gac-042644	Gasterosteus aculeatus	90.73	0.00e+00	687.00
IUUC-Ggo-044489	Gorilla gorilla	89.65	0.00e+00	738.00
IUUC-Hsa-046434	Homo sapiens	93.42	0.00e+00	780.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	91.77	9.00e-175	605.00
IUUC-Loc-052790	Lepisosteus oculatus	91.84	0.00e+00	731.00
IUUC-Laf-054255	Loxodonta africana	91.86	0.00e+00	765.00
IUUC-Mcc-055610	Macaca mulatta	93.38	0.00e+00	775.00
IUUC-Meu-056819	Macropus eugenii	82.65	0.00e+00	669.00
IUUC-Mga-059740	Meleagris gallopavo	87.53	0.00e+00	721.00
IUUC-Mmr-061221	Microcebus murinus	93.42	0.00e+00	779.00
IUUC-Mdo-062619	Monodelphis domestica	96.88	0.00e+00	717.00
IUUC-Mmu-064266	Mus musculus	92.66	0.00e+00	777.00
IUUC-Mpu-065766	Mustela putorius furo	97.01	2.00e-179	621.00
IUUC-Mlu-067221	Myotis lucifugus	86.15	0.00e+00	718.00
IUUC-Nle-069515	Nomascus leucogenys	97.47	0.00e+00	653.00
IUUC-Opr-070195	Ochotona princeps	85.24	0.00e+00	689.00
IUUC-Ont-071535	Oreochromis niloticus	80.51	7.00e-176	609.00
IUUC-Oan-072899	Ornithorhynchus anatinus	98.38	8.00e-108	382.00
IUUC-Ocu-074666	Oryctolagus cuniculus	98.01	2.00e-180	624.00
IUUC-Ola-086578	Oryzias latipes	92.33	0.00e+00	652.00
IUUC-Oga-089090	Otolemur garnettii	92.44	0.00e+00	773.00
IUUC-Oar-090017	Ovis aries	87.06	0.00e+00	709.00
IUUC-Ptr-091280	Pan troglodytes	84.56	0.00e+00	694.00
IUUC-Pan-092198	Papio anubis	96.86	0.00e+00	654.00
IUUC-Psi-093030	Pelodiscus sinensis	85.57	0.00e+00	722.00
IUUC-Pma-094140	Petromyzon marinus	79.34	4.00e-99	353.00
IUUC-Pfo-097182	Poecilia formosa	92.63	0.00e+00	667.00
IUUC-Pab-098157	Pongo abelii	97.45	0.00e+00	725.00
IUUC-Pca-100988	Procavia capensis	71.39	5.00e-160	556.00
IUUC-Pva-102232	Pteropus vampyrus	84.29	1.00e-173	602.00
IUUC-Rno-105526	Rattus norvegicus	93.24	0.00e+00	683.00
IUUC-Sce-106298	Saccharomyces cerevisiae	35.50	1.00e-67	249.00
IUUC-Sha-106754	Sarcophilus harrisii	93.16	0.00e+00	734.00
IUUC-Ssc-115390	Sus scrofa	93.18	0.00e+00	776.00
IUUC-Tgu-117377	Taeniopygia guttata	86.01	0.00e+00	696.00
IUUC-Tru-117938	Takifugu rubripes	92.63	0.00e+00	654.00
IUUC-Tsy-119392	Tarsius syrichta	78.73	0.00e+00	627.00
IUUC-Tni-119834	Tetraodon nigroviridis	74.68	1.00e-169	588.00
IUUC-Tbe-127469	Tupaia belangeri	91.22	0.00e+00	707.00
IUUC-Ttr-128252	Tursiops truncatus	90.91	0.00e+00	744.00
IUUC-Vpa-130173	Vicugna pacos	75.30	2.00e-149	521.00
IUUC-Xtr-131803	Xenopus tropicalis	94.68	0.00e+00	740.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence