iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106754

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01009487

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017321.1	ENSSHAT00000020582.1	ENSSHAP00000020421.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-42	141.2	235	276
UBD/Beta-Prp	3.20e-54	184.3	189	394

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllks 38
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++s
   Q: 235  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCIQS 276
           8***********9644499********************986 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 189  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCIQ-S 276
           567889999*********99***************************************9777************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 277  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 365
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 366  HENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
           ***************************** PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RALRPVFIRS QQLSYCAVCV ALMAAEGLHE NETLASLKSE 60
AESLKSKLEE ERAKLHDVEL HQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGCGATC AGACATTTTT GGTTAATGTA TTTGGATCCT GTGACAAATG TTTCAAGCAA 60
AGAGCTTTGA GACCAGTTTT TATCCGATCT CAACAACTCA GCTACTGTGC AGTATGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	90.38	0.00e+00	754.00
IUUC-Apl-003399	Anas platyrhynchos	99.36	0.00e+00	652.00
IUUC-Aca-004861	Anolis carolinensis	93.16	0.00e+00	779.00
IUUC-Ame-011851	Astyanax mexicanus	92.88	0.00e+00	691.00
IUUC-Bta-012438	Bos taurus	98.58	0.00e+00	728.00
IUUC-Cel-018408	Caenorhabditis elegans	64.93	1.00e-139	489.00
IUUC-Cja-019086	Callithrix jacchus	97.20	0.00e+00	802.00
IUUC-Cfa-021255	Canis familiaris	95.17	0.00e+00	749.00
IUUC-Cpo-021398	Cavia porcellus	94.70	0.00e+00	786.00
IUUC-Csa-023776	Chlorocebus sabaeus	98.58	0.00e+00	727.00
IUUC-Cin-025305	Ciona intestinalis	58.47	3.00e-132	464.00
IUUC-Csv-026058	Ciona savignyi	58.13	1.00e-128	452.00
IUUC-Dre-028432	Danio rerio	84.30	0.00e+00	680.00
IUUC-Dno-029958	Dasypus novemcinctus	83.79	1.00e-143	501.00
IUUC-Dor-031013	Dipodomys ordii	98.44	1.00e-152	532.00
IUUC-Dme-031889	Drosophila melanogaster	68.60	1.00e-149	521.00
IUUC-Ete-033033	Echinops telfairi	77.99	5.00e-95	340.00
IUUC-Eca-033977	Equus caballus	91.65	0.00e+00	757.00
IUUC-Eeu-035079	Erinaceus europaeus	96.17	0.00e+00	786.00
IUUC-Fca-035693	Felis catus	90.18	0.00e+00	750.00
IUUC-Fal-037345	Ficedula albicollis	98.02	0.00e+00	726.00
IUUC-Gmo-039222	Gadus morhua	91.01	0.00e+00	660.00
IUUC-Gga-040320	Gallus gallus	98.58	0.00e+00	728.00
IUUC-Gac-042644	Gasterosteus aculeatus	91.29	0.00e+00	691.00
IUUC-Ggo-044489	Gorilla gorilla	93.18	0.00e+00	766.00
IUUC-Hsa-046434	Homo sapiens	97.22	0.00e+00	807.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.04	3.00e-176	610.00
IUUC-Loc-052790	Lepisosteus oculatus	91.58	0.00e+00	728.00
IUUC-Laf-054255	Loxodonta africana	95.42	0.00e+00	790.00
IUUC-Mcc-055610	Macaca mulatta	96.69	0.00e+00	798.00
IUUC-Meu-056819	Macropus eugenii	87.76	0.00e+00	702.00
IUUC-Mga-059740	Meleagris gallopavo	87.53	0.00e+00	721.00
IUUC-Mmr-061221	Microcebus murinus	96.46	0.00e+00	802.00
IUUC-Mdo-062619	Monodelphis domestica	99.43	0.00e+00	731.00
IUUC-Mmu-064266	Mus musculus	96.46	0.00e+00	803.00
IUUC-Mpu-065766	Mustela putorius furo	98.67	0.00e+00	627.00
IUUC-Mlu-067221	Myotis lucifugus	89.42	0.00e+00	741.00
IUUC-Nle-069515	Nomascus leucogenys	99.05	0.00e+00	659.00
IUUC-Opr-070195	Ochotona princeps	88.55	0.00e+00	713.00
IUUC-Ont-071535	Oreochromis niloticus	78.99	5.00e-173	600.00
IUUC-Oan-072899	Ornithorhynchus anatinus	98.92	7.00e-108	382.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.00	0.00e+00	628.00
IUUC-Ola-086578	Oryzias latipes	92.90	0.00e+00	654.00
IUUC-Oga-089090	Otolemur garnettii	95.97	0.00e+00	798.00
IUUC-Oar-090017	Ovis aries	90.10	0.00e+00	734.00
IUUC-Ptr-091280	Pan troglodytes	88.35	0.00e+00	719.00
IUUC-Pan-092198	Papio anubis	98.43	0.00e+00	659.00
IUUC-Psi-093030	Pelodiscus sinensis	86.07	0.00e+00	726.00
IUUC-Pma-094140	Petromyzon marinus	83.10	1.00e-104	371.00
IUUC-Pfo-097182	Poecilia formosa	91.85	0.00e+00	669.00
IUUC-Pab-098157	Pongo abelii	98.87	0.00e+00	731.00
IUUC-Pca-100988	Procavia capensis	75.19	1.00e-167	582.00
IUUC-Pva-102232	Pteropus vampyrus	85.43	2.00e-175	607.00
IUUC-Rno-105526	Rattus norvegicus	94.65	0.00e+00	689.00
IUUC-Sce-106298	Saccharomyces cerevisiae	35.43	1.00e-67	250.00
IUUC-Ssc-115390	Sus scrofa	97.22	0.00e+00	803.00
IUUC-Tgu-117377	Taeniopygia guttata	86.77	0.00e+00	702.00
IUUC-Tru-117938	Takifugu rubripes	92.92	0.00e+00	655.00
IUUC-Tsy-119392	Tarsius syrichta	82.78	0.00e+00	654.00
IUUC-Tni-119834	Tetraodon nigroviridis	72.91	2.00e-166	578.00
IUUC-Tbe-127469	Tupaia belangeri	93.62	0.00e+00	719.00
IUUC-Ttr-128252	Tursiops truncatus	93.94	0.00e+00	765.00
IUUC-Vpa-130173	Vicugna pacos	78.57	4.00e-155	540.00
IUUC-Xtr-131803	Xenopus tropicalis	91.65	0.00e+00	731.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence