iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-070085

Ensembl Protein ID

ENSNLEP00000013752.1

UniProt Accession

G1RKJ5; G1RKJ5_NOMLE

Genbank Protein ID

ENSNLEP00000013752

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

ADFV01122152

Gene Name

KMT2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000011306.1	ENSNLET00000014430.1	ENSNLEP00000013752.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.00e-30	103.0	1245	1298

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++++  wiC+ C ++
   Q: 1245 KFCHVCGRKGRGSKHLLECERCRHAYHPACLGPS-YPTRATRKRrhWICSACVRC 1298
           58********************************.88888877777******876 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MAAAAGGGSC PGPGSARGRF PGRPRGAGGG GGRGGRGNGA ERVRVALRRG GGATGPGGAE 60
PGEDTALLRL LGLRRGLRRL RRLWAGPRVQ RGRGRGRGRG WGPSRGCVPE EESSDGESDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG CGGCGGGCGG CGGCAGTTGC CCCGGGCCTG GCTCCGCGCG GGGCCGCTTC 60
CCGGGCCGGC CGCGGGGCGC CGGCGGGGGC GGGGGCCGCG GCGGACGGGG CAACGGGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002367	Ailuropoda melanoleuca	89.61	0.00e+00	2281.00
IUUC-Aca-004718	Anolis carolinensis	64.11	0.00e+00	1379.00
IUUC-Ame-011927	Astyanax mexicanus	44.28	0.00e+00	852.00
IUUC-Bta-013578	Bos taurus	92.82	0.00e+00	2038.00
IUUC-Bdi-014882	Brachypodium distachyon	33.33	3.00e-27	116.00
IUUC-Bra-017422	Brassica rapa	33.50	1.00e-27	117.00
IUUC-Cja-019138	Callithrix jacchus	91.72	0.00e+00	2340.00
IUUC-Cfa-020020	Canis familiaris	90.49	0.00e+00	2175.00
IUUC-Cpo-021552	Cavia porcellus	87.10	0.00e+00	2176.00
IUUC-Csa-024216	Chlorocebus sabaeus	95.95	0.00e+00	2423.00
IUUC-Dre-027440	Danio rerio	44.68	0.00e+00	907.00
IUUC-Dno-029583	Dasypus novemcinctus	94.29	0.00e+00	2125.00
IUUC-Dor-030903	Dipodomys ordii	84.55	0.00e+00	2119.00
IUUC-Dme-032023	Drosophila melanogaster	47.56	5.00e-93	337.00
IUUC-Eca-034026	Equus caballus	95.18	0.00e+00	1880.00
IUUC-Eeu-034687	Erinaceus europaeus	93.36	0.00e+00	1136.00
IUUC-Fca-036311	Felis catus	88.70	0.00e+00	2271.00
IUUC-Gmo-039265	Gadus morhua	45.00	0.00e+00	811.00
IUUC-Gac-042202	Gasterosteus aculeatus	47.95	0.00e+00	741.00
IUUC-Ggo-044791	Gorilla gorilla	99.19	0.00e+00	2052.00
IUUC-Hsa-046988	Homo sapiens	96.44	0.00e+00	2290.00
IUUC-Hvu-047762	Hordeum vulgare	36.57	4.00e-20	92.80
IUUC-Itr-048907	Ictidomys tridecemlineatus	89.71	0.00e+00	2344.00
IUUC-Lpe-051476	Leersia perrieri	31.51	4.00e-24	106.00
IUUC-Loc-052252	Lepisosteus oculatus	53.73	0.00e+00	778.00
IUUC-Laf-053703	Loxodonta africana	92.15	0.00e+00	2051.00
IUUC-Mcc-054782	Macaca mulatta	94.72	0.00e+00	2474.00
IUUC-Meu-056046	Macropus eugenii	78.76	0.00e+00	1835.00
IUUC-Mmr-061316	Microcebus murinus	94.06	0.00e+00	1974.00
IUUC-Mdo-062648	Monodelphis domestica	80.58	0.00e+00	1872.00
IUUC-Mmu-063579	Mus musculus	88.61	0.00e+00	2246.00
IUUC-Mac-064935	Musa acuminata	32.02	9.00e-30	125.00
IUUC-Mpu-066710	Mustela putorius furo	90.01	0.00e+00	2229.00
IUUC-Mlu-067559	Myotis lucifugus	88.29	0.00e+00	2244.00
IUUC-Opr-071148	Ochotona princeps	85.90	0.00e+00	2222.00
IUUC-Ont-071626	Oreochromis niloticus	48.54	0.00e+00	780.00
IUUC-Ocu-074475	Oryctolagus cuniculus	88.37	0.00e+00	2185.00
IUUC-Obr-076458	Oryza brachyantha	34.48	6.00e-28	119.00
IUUC-Ogl-077851	Oryza glaberrima	36.26	4.00e-28	119.00
IUUC-Ogu-078706	Oryza glumaepatula	36.26	3.00e-28	120.00
IUUC-Oin-079802	Oryza indica	31.43	3.00e-23	103.00
IUUC-Osa-085421	Oryza sativa	36.26	6.00e-28	119.00
IUUC-Ola-086609	Oryzias latipes	51.04	0.00e+00	751.00
IUUC-Oga-088140	Otolemur garnettii	90.34	0.00e+00	2208.00
IUUC-Oar-089447	Ovis aries	91.13	0.00e+00	2034.00
IUUC-Ptr-090902	Pan troglodytes	96.19	0.00e+00	2294.00
IUUC-Pan-091930	Papio anubis	95.95	0.00e+00	2353.00
IUUC-Ppa-095221	Physcomitrella patens	36.54	8.00e-31	128.00
IUUC-Pfo-096884	Poecilia formosa	45.46	0.00e+00	875.00
IUUC-Pab-098404	Pongo abelii	98.36	0.00e+00	925.00
IUUC-Pop-099585	Populus trichocarpa	33.50	1.00e-26	114.00
IUUC-Pca-100949	Procavia capensis	86.11	0.00e+00	1220.00
IUUC-Ppe-101920	Prunus persica	33.01	1.00e-27	118.00
IUUC-Pva-102634	Pteropus vampyrus	88.58	0.00e+00	2249.00
IUUC-Rno-105870	Rattus norvegicus	88.42	0.00e+00	2330.00
IUUC-Sit-110552	Setaria italica	34.33	9.00e-29	121.00
IUUC-Sar-113289	Sorex araneus	89.87	0.00e+00	1656.00
IUUC-Ssc-115509	Sus scrofa	89.98	0.00e+00	2241.00
IUUC-Tru-118413	Takifugu rubripes	52.31	0.00e+00	779.00
IUUC-Tca-121624	Theobroma cacao	33.33	1.00e-27	118.00
IUUC-Tae-125629	Triticum aestivum	36.57	3.00e-20	93.20
IUUC-Tbe-127825	Tupaia belangeri	85.98	0.00e+00	1546.00
IUUC-Ttr-128754	Tursiops truncatus	94.15	0.00e+00	1240.00
IUUC-Xtr-132838	Xenopus tropicalis	49.50	0.00e+00	1013.00
IUUC-Xma-133119	Xiphophorus maculatus	44.68	0.00e+00	929.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence