iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000005740.3	ENSMMUT00000008060.3	ENSMMUP00000007577.3
ENSMMUG00000005740.3	ENSMMUT00000064324.1	ENSMMUP00000056274.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-78	266.0	1688	2040

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +Gl+N g+tCYmN+v Q+L++ p l e ll+     ++++  ++p+ ++  ++q+lf +l++sk +++ p++++k++k++++e+   
   Q: 1688 VGLRNGGATCYMNAVFQQLYMQPGLPESLLS-----VDDD-TDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVR 1768
           6******************************.....5444.468999**************************************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           eqqDa Ef++ l+dq++e+l                          kk+  +++ +++Fqg +++q +c++c ++++ree f+ l+l
   Q: 1769 EQQDAYEFFTSLIDQMDEYL--------------------------KKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNL 1829
           ********************..........................78999************************************ PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
            v + +     sl+ +L++f++ e leg+n+yycekck+k+ ++k++ +k+lP vL++hL+Rf f+ e ++++k ++++ fp +L++
   Q: 1830 GVTSCQ-----SLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNM 1911
           ******.....9*************************************************************************** PP
   S: 262  spfcts.....peekqke.........................kkkYeLiavvvHsGslssGHYvayvkn....ekgkWllfdDskV 314
           +p+++s     +     +                         +++YeL++v+vHsG+++ GHY++++k+     kgkW++f+D+ +
   Q: 1912 EPYTVSgmarqD-----SssevgengrsmdqggggsprkkvalTENYELVGVIVHSGQAHAGHYYSFIKDrrgcGKGKWYKFNDTVI 1993
           ******666550.....34445555566666666666666666***************************55555666********* PP
   S: 315  tevk.eeevleetg.......................staYvlfYkr 337
           +e +  +e le +                        ++aY+lfY+r
   Q: 1994 EEFDlNDETLEYECfggeyrpkvydqtnpytdvrrryWNAYMLFYQR 2040
           ***844666664449******************************98 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MESEEEQHMT TLLCMGFSDP ATIRKALRLA KNDINEAVAL LTNERPGLDY GGYEPMDSGG 60
GPSPGPGGGP RGDGGGDGGG GPSRGGSTGG GGGFDPPPAY HEVVDAEKND ENGNCSGEGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCCAACAT GGCGGCGCGC AGGGCTGGGC CGGGCAGCCG CCGCGCCTGA GCGCCCCACC 60
GCCCTAGCTC GGCTCGCAGA ACCCACGCCC GCACCCAGCC TGGCCTGCGG CTGCGGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR033382--USP24
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mcc:717178

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002266	Ailuropoda melanoleuca	98.93	0.00e+00	4839.00
IUUC-Apl-003203	Anas platyrhynchos	74.72	0.00e+00	3502.00
IUUC-Aca-004396	Anolis carolinensis	90.10	0.00e+00	4508.00
IUUC-Acl-008140	Aspergillus clavatus	28.67	8.00e-58	220.00
IUUC-Afl-008381	Aspergillus flavus	29.70	4.00e-56	214.00
IUUC-Afu-008857	Aspergillus fumigatus	29.88	2.00e-55	213.00
IUUC-Ang-009759	Aspergillus niger	30.37	2.00e-59	225.00
IUUC-Aor-009931	Aspergillus oryzae	29.70	5.00e-56	214.00
IUUC-Ate-010246	Aspergillus terreus	24.18	8.00e-52	200.00
IUUC-Ame-011886	Astyanax mexicanus	84.62	0.00e+00	1770.00
IUUC-Bta-013381	Bos taurus	98.01	0.00e+00	4900.00
IUUC-Cel-018352	Caenorhabditis elegans	29.97	5.00e-62	234.00
IUUC-Cja-018955	Callithrix jacchus	99.20	0.00e+00	4451.00
IUUC-Cfa-020720	Canis familiaris	98.93	0.00e+00	4832.00
IUUC-Cpo-022430	Cavia porcellus	96.12	0.00e+00	3450.00
IUUC-Csa-024180	Chlorocebus sabaeus	99.88	0.00e+00	4682.00
IUUC-Cho-025074	Choloepus hoffmanni	92.94	0.00e+00	1848.00
IUUC-Dre-027696	Danio rerio	80.79	0.00e+00	4090.00
IUUC-Dno-029307	Dasypus novemcinctus	96.04	0.00e+00	4778.00
IUUC-Dor-030889	Dipodomys ordii	95.34	0.00e+00	4622.00
IUUC-Ete-032294	Echinops telfairi	92.94	0.00e+00	2325.00
IUUC-Eca-033823	Equus caballus	92.99	0.00e+00	4520.00
IUUC-Eeu-035178	Erinaceus europaeus	89.07	0.00e+00	2125.00
IUUC-Fca-035444	Felis catus	98.89	0.00e+00	4770.00
IUUC-Fal-037555	Ficedula albicollis	92.87	0.00e+00	4529.00
IUUC-Fso-038108	Fusarium solani	31.59	4.00e-52	201.00
IUUC-Gmo-038587	Gadus morhua	80.25	0.00e+00	2496.00
IUUC-Gga-041231	Gallus gallus	92.33	0.00e+00	4640.00
IUUC-Gac-041584	Gasterosteus aculeatus	80.25	0.00e+00	2463.00
IUUC-Ggo-044502	Gorilla gorilla	99.39	0.00e+00	4913.00
IUUC-Hsa-045851	Homo sapiens	99.20	0.00e+00	4925.00
IUUC-Itr-048746	Ictidomys tridecemlineatus	98.44	0.00e+00	1586.00
IUUC-Lch-049999	Latimeria chalumnae	79.69	0.00e+00	3924.00
IUUC-Loc-051767	Lepisosteus oculatus	82.54	0.00e+00	4125.00
IUUC-Laf-054139	Loxodonta africana	98.40	0.00e+00	4889.00
IUUC-Meu-056659	Macropus eugenii	81.68	0.00e+00	2258.00
IUUC-Mga-059267	Meleagris gallopavo	93.16	0.00e+00	4569.00
IUUC-Mmr-060971	Microcebus murinus	97.08	0.00e+00	4840.00
IUUC-Mdo-061925	Monodelphis domestica	94.24	0.00e+00	4643.00
IUUC-Mmu-064019	Mus musculus	96.83	0.00e+00	4950.00
IUUC-Mpu-066652	Mustela putorius furo	98.89	0.00e+00	4947.00
IUUC-Mlu-067518	Myotis lucifugus	98.49	0.00e+00	4764.00
IUUC-Nfi-068259	Neosartorya fischeri	30.22	4.00e-56	214.00
IUUC-Nle-069763	Nomascus leucogenys	99.44	0.00e+00	4799.00
IUUC-Opr-071031	Ochotona princeps	91.80	0.00e+00	4419.00
IUUC-Ont-072136	Oreochromis niloticus	78.47	0.00e+00	4000.00
IUUC-Oan-072908	Ornithorhynchus anatinus	84.97	0.00e+00	965.00
IUUC-Ocu-073880	Oryctolagus cuniculus	97.29	0.00e+00	4893.00
IUUC-Ola-086544	Oryzias latipes	77.55	0.00e+00	3849.00
IUUC-Oga-088695	Otolemur garnettii	98.74	0.00e+00	4954.00
IUUC-Oar-089401	Ovis aries	98.17	0.00e+00	4749.00
IUUC-Ptr-091657	Pan troglodytes	99.64	0.00e+00	4819.00
IUUC-Pan-092394	Papio anubis	99.96	0.00e+00	4943.00
IUUC-Psi-093813	Pelodiscus sinensis	93.24	0.00e+00	4541.00
IUUC-Pma-094698	Petromyzon marinus	53.63	3.00e-137	481.00
IUUC-Pfo-096811	Poecilia formosa	79.10	0.00e+00	3986.00
IUUC-Pab-097814	Pongo abelii	99.66	0.00e+00	4932.00
IUUC-Pca-101135	Procavia capensis	93.34	0.00e+00	2230.00
IUUC-Pva-102334	Pteropus vampyrus	93.50	0.00e+00	4645.00
IUUC-Pte-104235	Pyrenophora teres	29.86	3.00e-50	195.00
IUUC-Rno-105040	Rattus norvegicus	96.64	0.00e+00	4900.00
IUUC-Sha-106658	Sarcophilus harrisii	94.72	0.00e+00	4658.00
IUUC-Sar-113153	Sorex araneus	87.04	0.00e+00	2751.00
IUUC-Ssc-115641	Sus scrofa	97.05	0.00e+00	4611.00
IUUC-Tgu-117467	Taeniopygia guttata	93.60	0.00e+00	3321.00
IUUC-Tru-118074	Takifugu rubripes	72.44	0.00e+00	3454.00
IUUC-Tsy-119165	Tarsius syrichta	94.51	0.00e+00	4531.00
IUUC-Tni-119923	Tetraodon nigroviridis	68.82	0.00e+00	3218.00
IUUC-Tbe-127910	Tupaia belangeri	91.15	0.00e+00	1819.00
IUUC-Ttr-128218	Tursiops truncatus	97.29	0.00e+00	4757.00
IUUC-Vpa-130090	Vicugna pacos	98.96	0.00e+00	1735.00
IUUC-Xtr-131911	Xenopus tropicalis	86.20	0.00e+00	1710.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence