iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093884

Ensembl Protein ID

ENSPSIP00000017270.1

UniProt Accession

K7GAF9; K7GAF9_PELSI

Genbank Protein ID

ENSPSIP00000017270

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01004450

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000015370.1	ENSPSIT00000017348.1	ENSPSIP00000017270.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.40e-19	67.7	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.80e-08	32.0	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es   ++v+++d + pe ++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGNRSFPCHRAVLAASSRYFEAMFSNGLRESL-DDEVNFHDsLHPEILELLLDFAYSSQIIINE 114
           7************************************9.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d ++c++L++   +++l +F+
   Q: 146  PSNCLGMMLLSDVHQCRRLYELSWRMCLVNFE 177
           89****************************95 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MSVSVHENRK SRTSTGSMNI LLFHKTSHPD CVLSHLNTFR KCCMFTDVTL WAGNRSFPCH 60
RAVLAASSRY FEAMFSNGLR ESLDDEVNFH DSLHPEILEL LLDFAYSSQI IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATACCTCTG TCATCATGTC GGTCAGCGTC CACGAGAACC GTAAATCCCG AACGAGCACC 60
GGCTCGATGA ATATCTTGCT TTTCCACAAA ACCTCCCACC CAGATTGTGT CCTGTCCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

KEGG

pss:102453449

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	89.98	0.00e+00	1128.00
IUUC-Apl-003543	Anas platyrhynchos	95.08	0.00e+00	1149.00
IUUC-Aca-004729	Anolis carolinensis	92.02	0.00e+00	1120.00
IUUC-Ame-011020	Astyanax mexicanus	86.42	0.00e+00	1049.00
IUUC-Bta-012955	Bos taurus	88.12	0.00e+00	1111.00
IUUC-Cja-018839	Callithrix jacchus	89.13	0.00e+00	1115.00
IUUC-Cfa-020224	Canis familiaris	90.15	0.00e+00	1126.00
IUUC-Cpo-021593	Cavia porcellus	86.42	0.00e+00	1045.00
IUUC-Csa-023276	Chlorocebus sabaeus	89.81	0.00e+00	1123.00
IUUC-Cho-024542	Choloepus hoffmanni	75.38	0.00e+00	932.00
IUUC-Dre-028053	Danio rerio	86.76	0.00e+00	1027.00
IUUC-Dno-029287	Dasypus novemcinctus	87.44	0.00e+00	1099.00
IUUC-Dor-030908	Dipodomys ordii	81.32	0.00e+00	996.00
IUUC-Dse-031490	Dothistroma septosporum	28.08	6.00e-06	43.90
IUUC-Ete-032817	Echinops telfairi	71.99	0.00e+00	878.00
IUUC-Eca-033651	Equus caballus	75.55	0.00e+00	933.00
IUUC-Fca-035897	Felis catus	89.98	0.00e+00	1126.00
IUUC-Fal-037036	Ficedula albicollis	95.42	0.00e+00	1154.00
IUUC-Gmo-039345	Gadus morhua	85.57	0.00e+00	1009.00
IUUC-Gga-040404	Gallus gallus	95.59	0.00e+00	1159.00
IUUC-Gac-042447	Gasterosteus aculeatus	85.74	0.00e+00	1024.00
IUUC-Ggo-045060	Gorilla gorilla	89.81	0.00e+00	1122.00
IUUC-Hsa-046494	Homo sapiens	89.98	0.00e+00	1124.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	90.49	0.00e+00	1128.00
IUUC-Lch-050211	Latimeria chalumnae	87.59	0.00e+00	1065.00
IUUC-Loc-052578	Lepisosteus oculatus	85.91	0.00e+00	1052.00
IUUC-Laf-053498	Loxodonta africana	89.98	0.00e+00	1077.00
IUUC-Mcc-055033	Macaca mulatta	89.81	0.00e+00	1124.00
IUUC-Meu-056893	Macropus eugenii	93.04	0.00e+00	1152.00
IUUC-Mga-060025	Meleagris gallopavo	95.93	0.00e+00	1162.00
IUUC-Mmr-060658	Microcebus murinus	88.79	0.00e+00	1117.00
IUUC-Mdo-062667	Monodelphis domestica	93.38	0.00e+00	1153.00
IUUC-Mmu-063125	Mus musculus	87.95	0.00e+00	1064.00
IUUC-Mpu-066209	Mustela putorius furo	89.64	0.00e+00	1124.00
IUUC-Mlu-068237	Myotis lucifugus	86.93	0.00e+00	1067.00
IUUC-Nle-069454	Nomascus leucogenys	89.71	0.00e+00	1108.00
IUUC-Opr-070238	Ochotona princeps	75.38	0.00e+00	929.00
IUUC-Ont-072138	Oreochromis niloticus	86.76	0.00e+00	1018.00
IUUC-Oan-073320	Ornithorhynchus anatinus	84.21	0.00e+00	1057.00
IUUC-Ocu-073765	Oryctolagus cuniculus	84.72	0.00e+00	1041.00
IUUC-Ome-081176	Oryza meridionalis	29.59	2.00e-07	50.10
IUUC-Oga-088002	Otolemur garnettii	88.96	0.00e+00	1109.00
IUUC-Oar-089481	Ovis aries	87.61	0.00e+00	1106.00
IUUC-Ptr-091200	Pan troglodytes	89.81	0.00e+00	1120.00
IUUC-Pan-092098	Papio anubis	75.55	0.00e+00	933.00
IUUC-Pma-094515	Petromyzon marinus	58.96	0.00e+00	659.00
IUUC-Pno-095143	Phaeosphaeria nodorum	27.31	7.00e-14	71.20
IUUC-Pfo-097496	Poecilia formosa	75.04	0.00e+00	947.00
IUUC-Pab-098388	Pongo abelii	75.55	0.00e+00	933.00
IUUC-Pca-100511	Procavia capensis	69.61	0.00e+00	842.00
IUUC-Pva-102321	Pteropus vampyrus	88.96	0.00e+00	1112.00
IUUC-Pyt-104594	Pyrenophora triticirepentis	38.33	4.00e-04	40.00
IUUC-Rno-104835	Rattus norvegicus	87.78	0.00e+00	1061.00
IUUC-Sha-107528	Sarcophilus harrisii	93.21	0.00e+00	1154.00
IUUC-Sar-113403	Sorex araneus	75.21	0.00e+00	954.00
IUUC-Ssc-116161	Sus scrofa	89.64	0.00e+00	1121.00
IUUC-Tgu-116569	Taeniopygia guttata	95.25	0.00e+00	1150.00
IUUC-Tru-117890	Takifugu rubripes	74.87	0.00e+00	947.00
IUUC-Tni-120525	Tetraodon nigroviridis	76.31	0.00e+00	887.00
IUUC-Ttr-129297	Tursiops truncatus	89.13	0.00e+00	1118.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence