iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054240

Ensembl Protein ID

ENSLAFP00000005980.3

UniProt Accession

G5E6Y1; G5E6Y1_LOXAF

Protein Name

Uncharacterized protein

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000007110.3	ENSLAFT00000007113.3	ENSLAFP00000005980.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.60e-27	92.6	910	944
UBD/Beta-Prp	1.40e-61	208.6	863	1041

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtg 33
           gHt++v+c++ f  +tl +s+s D+t+++W+l +g
   Q: 910  GHTGEVRCVKvFaKGTLAISASKDHTLRLWNLLSG 944
           8********9778669***************9776 PP

UBD/Beta-Prp

   S: 87   vhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllr 173
            +tl+g  + ++++++s +   lv+G++d t+ vwd+++ q+++ +l+gh+g v+cv+v  +g l +s+s+D t+rlW+l +g+   
   Q: 863  RVTLTGCHKGITAMAWSLEELLLVVGTQDGTVAVWDMKEHQVIH-ILAGHTGEVRCVKVFAKGTLAISASKDHTLRLWNLLSGQEKF 948
           56677777777777777777777777777777777777777777.777777777777777777777777777777777776666666 PP
   S: 174  tl.tgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlng.htdnvksvrfspnderlvsgssDgsiriWdlrsgd 255
           t   gg +d+ +s       ++ + +v+    ++v+ w+l+t e v    g  +d   + +++  + rl+ +s  g++++W + +g+
   Q: 949  TIrDGGSKDPTESQFwnlHLDEANKVVYSTSGSKVNAWNLETAEPVFHILGdASDAWVCTAVFASQARLLMVSVRGVVSLWSSATGK 1035
           664333444444433223223347777777777777777776666544443244444445555577777777777777777777777 PP
   S: 256  llktlq 261
           + ++ q
   Q: 1036 PQGKQQ 1041
           666555 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MDTEREALQK SAYPEVQTFC QKHGLMFEVV DLRWGVRNTE ATDHLTTELC LEEIDRCQKT 60
SIGPTFVALV GDQYGPCVVP PLIEEKEWEA LRAQLKTRPR DLELVARRFR KDENAVPPAY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACACAG AGAGGGAAGC CCTGCAAAAG TCAGCCTACC CCGAAGTGCA AACCTTCTGC 60
CAGAAGCACG GCCTGATGTT CGAGGTAAGT GCCTACCTGC TCCTCCCTGC CTCAGTTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

KEGG

lav:100654136

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	83.78	0.00e+00	2628.00
IUUC-Apl-003467	Anas platyrhynchos	62.66	1.00e-87	315.00
IUUC-Ame-011400	Astyanax mexicanus	36.35	0.00e+00	983.00
IUUC-Bta-013223	Bos taurus	82.19	0.00e+00	2216.00
IUUC-Cel-018404	Caenorhabditis elegans	28.67	2.00e-99	357.00
IUUC-Cja-018773	Callithrix jacchus	80.10	0.00e+00	1529.00
IUUC-Cfa-020334	Canis familiaris	84.02	0.00e+00	2626.00
IUUC-Cpo-022316	Cavia porcellus	66.88	0.00e+00	1946.00
IUUC-Csa-023631	Chlorocebus sabaeus	82.25	0.00e+00	2543.00
IUUC-Cin-025646	Ciona intestinalis	32.19	4.00e-126	445.00
IUUC-Csv-026191	Ciona savignyi	24.74	8.00e-25	107.00
IUUC-Dre-028241	Danio rerio	36.28	0.00e+00	949.00
IUUC-Dno-029990	Dasypus novemcinctus	80.54	0.00e+00	718.00
IUUC-Dor-030869	Dipodomys ordii	62.08	4.00e-177	615.00
IUUC-Ete-033059	Echinops telfairi	88.61	0.00e+00	897.00
IUUC-Eca-033718	Equus caballus	78.89	0.00e+00	2464.00
IUUC-Fca-035748	Felis catus	82.66	0.00e+00	2393.00
IUUC-Gac-041507	Gasterosteus aculeatus	35.64	0.00e+00	740.00
IUUC-Ggo-044551	Gorilla gorilla	78.76	0.00e+00	2415.00
IUUC-Hsa-046787	Homo sapiens	81.57	0.00e+00	2543.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	65.26	0.00e+00	1850.00
IUUC-Lch-049578	Latimeria chalumnae	47.94	0.00e+00	1421.00
IUUC-Loc-052039	Lepisosteus oculatus	41.94	0.00e+00	1237.00
IUUC-Mcc-054657	Macaca mulatta	74.97	0.00e+00	2190.00
IUUC-Meu-056591	Macropus eugenii	64.40	0.00e+00	1176.00
IUUC-Mmr-061577	Microcebus murinus	79.24	0.00e+00	2432.00
IUUC-Mdo-062895	Monodelphis domestica	62.35	0.00e+00	1778.00
IUUC-Mmu-063866	Mus musculus	77.33	0.00e+00	2393.00
IUUC-Mpu-066510	Mustela putorius furo	82.89	0.00e+00	2620.00
IUUC-Mlu-067855	Myotis lucifugus	83.27	0.00e+00	2543.00
IUUC-Nle-069557	Nomascus leucogenys	77.66	0.00e+00	2333.00
IUUC-Opr-071196	Ochotona princeps	62.39	0.00e+00	635.00
IUUC-Ont-072070	Oreochromis niloticus	36.08	0.00e+00	818.00
IUUC-Oan-073437	Ornithorhynchus anatinus	58.34	0.00e+00	1269.00
IUUC-Ocu-074941	Oryctolagus cuniculus	81.82	2.00e-52	198.00
IUUC-Ola-086624	Oryzias latipes	33.31	0.00e+00	674.00
IUUC-Oga-088313	Otolemur garnettii	83.66	0.00e+00	2352.00
IUUC-Oar-090123	Ovis aries	81.74	0.00e+00	2552.00
IUUC-Ptr-090552	Pan troglodytes	84.40	0.00e+00	1113.00
IUUC-Psi-093963	Pelodiscus sinensis	54.55	0.00e+00	1613.00
IUUC-Pfo-096197	Poecilia formosa	35.40	0.00e+00	818.00
IUUC-Pab-097755	Pongo abelii	83.39	0.00e+00	936.00
IUUC-Pca-100809	Procavia capensis	87.69	0.00e+00	1350.00
IUUC-Pva-102554	Pteropus vampyrus	79.27	0.00e+00	2216.00
IUUC-Rno-105174	Rattus norvegicus	70.63	0.00e+00	2111.00
IUUC-Sha-107304	Sarcophilus harrisii	62.01	0.00e+00	1986.00
IUUC-Sar-113168	Sorex araneus	65.96	0.00e+00	1386.00
IUUC-Tru-118251	Takifugu rubripes	36.28	0.00e+00	661.00
IUUC-Tsy-119276	Tarsius syrichta	81.23	2.00e-124	441.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence