iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052853

Ensembl Protein ID

ENSLOCP00000001862.1

UniProt Accession

W5M0F5; W5M0F5_LEPOC

Genbank Protein ID

ENSLOCP00000001862

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01003344

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000001608.1	ENSLOCT00000001867.1	ENSLOCP00000001862.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-30	104.1	368	401
UBD/Beta-Prp	5.50e-52	176.9	329	553

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           Htd+v +++f ++ +++vsGs+Dgt ++W l ++
   Q: 368  HTDKVDSIQFcNTgDRFVSGSRDGTARIWKLQQQ 401
           ***********777****************9765 PP

UBD/Beta-Prp

   S: 56   tavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee........... 131
            + +fsp g +l+tgs+D++i+++ l   +++  + l++h+d+v s++f+ +gd++vsGs+d t+r+w+l+++ + +            
   Q: 329  VCSSFSPGGMFLATGSTDHVIRIYYLGggSPERCSELEAHTDKVDSIQFCNTGDRFVSGSRDGTARIWKLQQQRWRSIlldmatnlpgs 417
           5788********************88855777899999*************************************9999********** PP
   S: 132  .....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtg 212
                 +s  ++ v++v+++  +  ++++ ++  +++W++ tg+ll+ l+g h+d v  l+   fds  + l+s+++dg v +wd+ +g
   Q: 418  apaaaEESFFKSKVTMVAWDRHDHSVITAVNNHLLKVWNSYTGQLLHVLKG-HEDEVFVLEphpFDS--RILLSAGHDGNVFIWDVVRG 503
           *999878888899*************************************9.*********877777..9*****************88 PP
   S: 213  ecvrtlnght.....dnvksvrfspnderlvsgssDgsiriWdlrsgdll 257
           +  + + +         v + +fsp++++++++ s+g + i+   s+++ 
   Q: 504  TKTQHYFNMIegqghGAVFDCKFSPDGQHFACTDSHGHLIIFGFGSSKPY 553
           884444443333334567778999*********99999988877666665 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MAGTTAKSQS VSLLESELYY LISRFLTTGP CRRAAQVLAS ELEEYEKLLP RRLDWRGDEH 60
PRSYEDLVRA NSHVAPDHLL QICRQLGPLL DRQVPSCVPG VGSLLGAGRH SALRLDKDFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCACGA GCACCCTCGG CGGTGACGTC ACCCCCCCAG GGCGGGCCGA ACCACAGCGC 60
GGAAAAACAC GGCCAGGCAG CGTCTCCCAA CCAGCCCGGC ATCGCCAGTG CGCGGCGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	32.41	8.00e-63	236.00
IUUC-Apl-004083	Anas platyrhynchos	59.91	0.00e+00	1616.00
IUUC-Ame-010718	Astyanax mexicanus	75.95	0.00e+00	1301.00
IUUC-Bdi-014797	Brachypodium distachyon	29.29	2.00e-58	221.00
IUUC-Bra-017961	Brassica rapa	31.12	9.00e-71	262.00
IUUC-Cja-019966	Callithrix jacchus	66.88	0.00e+00	1842.00
IUUC-Cpo-021934	Cavia porcellus	67.18	0.00e+00	1862.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	36.36	2.00e-33	137.00
IUUC-Cho-024690	Choloepus hoffmanni	78.12	2.00e-178	620.00
IUUC-Dre-028205	Danio rerio	74.42	0.00e+00	1283.00
IUUC-Fal-037307	Ficedula albicollis	66.24	0.00e+00	1888.00
IUUC-Gga-040865	Gallus gallus	66.55	0.00e+00	1901.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	65.37	0.00e+00	710.00
IUUC-Meu-056739	Macropus eugenii	62.94	0.00e+00	885.00
IUUC-Mmr-061227	Microcebus murinus	66.41	0.00e+00	1865.00
IUUC-Mdo-062074	Monodelphis domestica	71.41	0.00e+00	1161.00
IUUC-Mmu-064075	Mus musculus	66.64	0.00e+00	1850.00
IUUC-Nle-069402	Nomascus leucogenys	66.46	0.00e+00	1828.00
IUUC-Ont-072298	Oreochromis niloticus	72.79	0.00e+00	2075.00
IUUC-Oan-072954	Ornithorhynchus anatinus	66.71	0.00e+00	1902.00
IUUC-Ocu-074456	Oryctolagus cuniculus	66.45	0.00e+00	1840.00
IUUC-Oba-075709	Oryza barthii	29.46	2.00e-60	228.00
IUUC-Oru-085195	Oryza rufipogon	29.46	3.00e-60	228.00
IUUC-Olu-087745	Ostreococcus lucimarinus	26.17	4.00e-54	206.00
IUUC-Psi-093271	Pelodiscus sinensis	66.46	0.00e+00	1682.00
IUUC-Ppa-095793	Physcomitrella patens	29.51	7.00e-70	259.00
IUUC-Pfo-097318	Poecilia formosa	71.32	0.00e+00	1937.00
IUUC-Rno-105687	Rattus norvegicus	65.97	0.00e+00	1820.00
IUUC-Sit-110017	Setaria italica	28.39	6.00e-57	216.00
IUUC-Tgu-116513	Taeniopygia guttata	65.52	0.00e+00	1885.00
IUUC-Tru-117824	Takifugu rubripes	65.31	0.00e+00	1812.00
IUUC-Tni-120656	Tetraodon nigroviridis	65.22	0.00e+00	1813.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence