iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071664

Ensembl Protein ID

ENSONIP00000007255.1

UniProt Accession

I3JEG4; I3JEG4_ORENI

Genbank Protein ID

ENSONIP00000007255

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01007839

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000005755.1	ENSONIT00000007260.1	ENSONIP00000007255.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.70e-134	448.2	618	948

Active Site

Position(s)	Description	Evidence
918	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           + lk+rl+vef gE+gld+gGv+re+++l+ske++np++glf+ys++d++tlq+np+sgl+n++hl +F+f+Gr+ g+a+++g+lld++
   Q: 618  DLLKARLWVEFDGEKGLDYGGVAREWFFLMSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLTYFKFIGRVAGMAVFHGKLLDAF 706
           66899************************************************************************************ PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           + ++fyk++lgk+++l+d+e+vd+e+++slk+i+en   d ++  ld++f+++ee++g+t++++Lkp+G++i VtneNk+eY++lv+++
   Q: 707  FIRPFYKMMLGKPITLQDMESVDSEYFNSLKWILEN---DPTD--LDMRFTIDEELFGQTHQHDLKPDGSEIVVTNENKDEYIHLVIQW 790
           **********************************99...6666..68999999************************************ PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+ ++i++q++af+eGf e++p++l+++F+e+elell+cG  ++dv+d++++tkyk+gy +++ +iqwFw+++  +++e+r ++LqFvT
   Q: 791  RFVNRIQKQMTAFKEGFFELVPQDLIKIFDENELELLMCGLGDVDVNDWRANTKYKNGYCSNHMVIQWFWKAVLLMDAEKRIRLLQFVT 879
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           g+sr+P++Gfael     p+lf+i+ +++ ++lP+++TCfn+L+LP+Y+s e+l+ekL +Aie+++gF+
   Q: 880  GTSRVPMNGFAELYgsngPQLFTIELWGTREKLPRAHTCFNRLDLPPYESFEELREKLNIAIENAQGFD 948
           ********************************************************************8 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

IMASVSSQIS GLQTDEEDNR ILKVKVIAGI GLAKKDILGA SDPYTRLSLY DPVTGEIASL 60
QTKTIKKTLD PKWNEEFFFR VDPKKHRLLF EVFDENRLTR DDFLGQVDVP LNQIPTENPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCATGGCTT CAGTTTCTTC ACAGATCTCA GGACTTCAGA CAGATGAGGT AAACTTGGCG 60
GTTTGTAAAC GAGGCCGCTG TCGTTAGCCA GCTAACCAAC GCCAGCTAAC CTAGAAACTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003886	Anas platyrhynchos	66.56	0.00e+00	1251.00
IUUC-Acl-008273	Aspergillus clavatus	48.33	8.00e-159	554.00
IUUC-Afl-008713	Aspergillus flavus	47.82	1.00e-154	540.00
IUUC-Afu-009103	Aspergillus fumigatus	48.49	4.00e-159	555.00
IUUC-Ani-009259	Aspergillus nidulans	48.25	5.00e-157	548.00
IUUC-Ang-009738	Aspergillus niger	48.50	2.00e-155	543.00
IUUC-Ate-010529	Aspergillus terreus	48.24	2.00e-157	550.00
IUUC-Ame-011138	Astyanax mexicanus	89.79	0.00e+00	896.00
IUUC-Bta-012453	Bos taurus	82.96	0.00e+00	855.00
IUUC-Cel-018564	Caenorhabditis elegans	51.77	3.00e-177	615.00
IUUC-Cpo-021648	Cavia porcellus	67.16	0.00e+00	1244.00
IUUC-Cin-025157	Ciona intestinalis	63.08	0.00e+00	797.00
IUUC-Csv-026098	Ciona savignyi	58.13	0.00e+00	655.00
IUUC-Dre-027924	Danio rerio	70.13	0.00e+00	1123.00
IUUC-Dse-031241	Dothistroma septosporum	46.52	4.00e-157	548.00
IUUC-Ete-032409	Echinops telfairi	75.76	0.00e+00	789.00
IUUC-Eca-033441	Equus caballus	67.33	0.00e+00	1217.00
IUUC-Fca-036384	Felis catus	67.67	0.00e+00	1122.00
IUUC-Fal-037547	Ficedula albicollis	68.12	0.00e+00	1259.00
IUUC-Fox-037774	Fusarium oxysporum	48.99	8.00e-159	554.00
IUUC-Fso-038393	Fusarium solani	47.31	3.00e-153	535.00
IUUC-Gmo-039679	Gadus morhua	71.40	0.00e+00	1347.00
IUUC-Gga-040524	Gallus gallus	67.64	0.00e+00	1261.00
IUUC-Gac-042607	Gasterosteus aculeatus	75.89	0.00e+00	1444.00
IUUC-Itr-048383	Ictidomys tridecemlineatus	66.93	0.00e+00	843.00
IUUC-Lch-050445	Latimeria chalumnae	69.94	0.00e+00	1170.00
IUUC-Loc-052645	Lepisosteus oculatus	73.78	0.00e+00	1387.00
IUUC-Meu-056897	Macropus eugenii	87.80	2.00e-157	550.00
IUUC-Mla-058996	Melampsora laricipopulina	54.45	4.00e-150	525.00
IUUC-Mga-059362	Meleagris gallopavo	68.87	0.00e+00	1267.00
IUUC-Mpu-066567	Mustela putorius furo	68.97	0.00e+00	1278.00
IUUC-Mlu-068148	Myotis lucifugus	68.07	0.00e+00	1126.00
IUUC-Nfi-068427	Neosartorya fischeri	48.49	2.00e-159	556.00
IUUC-Ncr-068918	Neurospora crassa	47.88	1.00e-155	543.00
IUUC-Oan-073019	Ornithorhynchus anatinus	69.32	0.00e+00	1212.00
IUUC-Pno-095118	Phaeosphaeria nodorum	47.47	2.00e-156	546.00
IUUC-Pfo-097145	Poecilia formosa	77.36	0.00e+00	1392.00
IUUC-Pab-098394	Pongo abelii	68.69	0.00e+00	1252.00
IUUC-Pca-100568	Procavia capensis	60.54	0.00e+00	907.00
IUUC-Pte-104016	Pyrenophora teres	48.56	8.00e-158	551.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	48.56	8.00e-158	551.00
IUUC-Tgu-117474	Taeniopygia guttata	68.51	0.00e+00	1280.00
IUUC-Tru-117675	Takifugu rubripes	75.87	0.00e+00	1398.00
IUUC-Tni-119993	Tetraodon nigroviridis	73.83	0.00e+00	1345.00
IUUC-Tbe-127408	Tupaia belangeri	62.64	0.00e+00	862.00
IUUC-Vda-129753	Verticillium dahliae	47.16	7.00e-154	538.00
IUUC-Vpa-130503	Vicugna pacos	82.57	0.00e+00	839.00
IUUC-Xtr-132431	Xenopus tropicalis	66.32	0.00e+00	1238.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence