iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004924

UUCD1 version

UUC-AnC-00973

Ensembl Protein ID

ENSACAP00000002037.2

UniProt Accession

G1KA98; G1KA98_ANOCA

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000002035.3	ENSACAT00000002086.3	ENSACAP00000002037.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	2.20e-63	214.6	4	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftl.lvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakq 93
           ++wl+Le++P++ ++ +++++g++  +q+ ++y++dpe l+++++pv+++lllF+++ek+e++r+++   n+++  ++++  t++f+kq
   Q: 4    HRWLPLEANPDVTNQqFLKQLGIQPSWQFVDVYGMDPELLSMVPRPVCAILLLFPVTEKYETFRTEE--ENKIKAEGQEVKPTVYFMKQ 90
           58***********95489**********************************************555..7899**************** PP
   S: 94   vigNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfv 181
           +i+N+C+t++l+++++n+ dk+ ++  + l+++++ +  + pe++a+ l++ ++++++h+s a+++++++p+ +       +k  +hf+
   Q: 91   TISNACGTIGLIHAIANNRDKItFEADSSLKKFLDDSVHMNPEERAKFLETYEAIRVTHESSAHEGQTEAPSID-------EKVDLHFI 172
           ***********************************************************************888.......8899**** PP
   S: 182  syvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaiva 243
           ++vn++g lyeldg+kpfP+++g++++++ l+d+++v+++f+er    + de+rfn++a++ 
   Q: 173  ALVNVGGILYELDGRKPFPINHGQSSDDTFLEDAIEVCKKFMER----DPDELRFNAIALST 230
           ********************************************....**********9875 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MEPHRWLPLE ANPDVTNQQF LKQLGIQPSW QFVDVYGMDP ELLSMVPRPV CAILLLFPVT 60
EKYETFRTEE ENKIKAEGQE VKPTVYFMKQ TISNACGTIG LIHAIANNRD KITFEADSSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAACCCC ACCGCTGGCT GCCGCTGGAG GCGAACCCTG ACGTGAGAGC CGGGGAGGGG 60
GAAGGGAAGG GAGGAGAAGA GAGGAGGGAG GGGGCGTGGC TTTCCCAGCG CGAGGCGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	42.13	2.00e-47	181.00
IUUC-Aml-001344	Ailuropoda melanoleuca	82.68	2.00e-115	407.00
IUUC-Atr-002931	Amborella trichopoda	47.20	2.00e-47	181.00
IUUC-Apl-003949	Anas platyrhynchos	87.32	6.00e-104	369.00
IUUC-Aly-005939	Arabidopsis lyrata	50.44	3.00e-55	207.00
IUUC-Ath-006827	Arabidopsis thaliana	50.88	3.00e-56	211.00
IUUC-Ago-007950	Ashbya gossypii	34.21	4.00e-27	114.00
IUUC-Acl-008305	Aspergillus clavatus	37.22	2.00e-35	142.00
IUUC-Afl-008611	Aspergillus flavus	39.57	3.00e-40	157.00
IUUC-Afu-008945	Aspergillus fumigatus	37.87	6.00e-38	150.00
IUUC-Ani-009339	Aspergillus nidulans	38.14	8.00e-39	153.00
IUUC-Ang-009691	Aspergillus niger	37.18	4.00e-38	150.00
IUUC-Aor-009961	Aspergillus oryzae	39.57	4.00e-40	157.00
IUUC-Ate-010316	Aspergillus terreus	38.14	3.00e-39	154.00
IUUC-Ame-011157	Astyanax mexicanus	74.46	7.00e-102	362.00
IUUC-Bgr-012125	Blumeria graminis	35.04	8.00e-38	150.00
IUUC-Bta-012673	Bos taurus	81.82	2.00e-114	404.00
IUUC-Bci-013734	Botrytis cinerea	38.03	7.00e-40	156.00
IUUC-Bdi-014330	Brachypodium distachyon	45.13	1.00e-51	196.00
IUUC-Bol-015214	Brassica oleracea	50.88	3.00e-57	214.00
IUUC-Bra-017491	Brassica rapa	51.33	5.00e-57	213.00
IUUC-Cel-018302	Caenorhabditis elegans	38.12	5.00e-33	134.00
IUUC-Cfa-020371	Canis familiaris	80.53	3.00e-91	327.00
IUUC-Cpo-022036	Cavia porcellus	80.95	2.00e-111	394.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	43.26	5.00e-35	140.00
IUUC-Csa-023854	Chlorocebus sabaeus	82.25	3.00e-114	404.00
IUUC-Cin-025545	Ciona intestinalis	51.75	7.00e-68	249.00
IUUC-Cgl-026659	Colletotrichum gloeosporioides	32.76	4.00e-29	120.00
IUUC-Cne-026914	Cryptococcus neoformans	36.97	8.00e-34	136.00
IUUC-Cme-027216	Cyanidioschyzon merolae	39.01	1.00e-28	119.00
IUUC-Dre-028356	Danio rerio	72.29	3.00e-99	353.00
IUUC-Dse-031461	Dothistroma septosporum	38.82	3.00e-34	138.00
IUUC-Dme-032146	Drosophila melanogaster	47.58	5.00e-59	220.00
IUUC-Eca-033220	Equus caballus	82.25	3.00e-114	404.00
IUUC-Fca-036421	Felis catus	82.68	2.00e-115	407.00
IUUC-Fal-036773	Ficedula albicollis	87.10	5.00e-104	370.00
IUUC-Fox-037830	Fusarium oxysporum	36.64	1.00e-39	155.00
IUUC-Fso-038259	Fusarium solani	34.93	6.00e-35	142.00
IUUC-Gmo-039468	Gadus morhua	71.43	5.00e-88	316.00
IUUC-Ggr-039832	Gaeumannomyces graminis	35.50	3.00e-34	138.00
IUUC-Gga-041205	Gallus gallus	86.58	3.00e-112	397.00
IUUC-Gac-041629	Gasterosteus aculeatus	69.87	5.00e-89	319.00
IUUC-Gma-043057	Glycine max	46.90	2.00e-47	182.00
IUUC-Ggo-044533	Gorilla gorilla	83.12	2.00e-117	414.00
IUUC-Hsa-046754	Homo sapiens	82.68	2.00e-115	407.00
IUUC-Hvu-047176	Hordeum vulgare	38.60	1.00e-39	156.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	77.99	3.00e-74	270.00
IUUC-Kpa-049123	Komagataella pastoris	34.55	3.00e-27	114.00
IUUC-Lch-049685	Latimeria chalumnae	78.17	3.00e-107	380.00
IUUC-Lpe-051377	Leersia perrieri	44.06	3.00e-42	164.00
IUUC-Loc-051988	Lepisosteus oculatus	76.19	2.00e-105	374.00
IUUC-Lma-053316	Leptosphaeria maculans	39.66	3.00e-42	164.00
IUUC-Laf-053985	Loxodonta africana	83.12	1.00e-117	415.00
IUUC-Mcc-055888	Macaca mulatta	80.95	3.00e-112	397.00
IUUC-Mor-057271	Magnaporthe oryzae	37.39	1.00e-40	159.00
IUUC-Mtr-057713	Medicago truncatula	47.35	7.00e-52	196.00
IUUC-Mla-058942	Melampsora laricipopulina	45.61	1.00e-46	179.00
IUUC-Mga-059702	Meleagris gallopavo	86.85	2.00e-103	367.00
IUUC-Mvi-060249	Microbotryum violaceum	41.92	6.00e-37	147.00
IUUC-Mmr-061284	Microcebus murinus	79.87	3.00e-75	274.00
IUUC-Mdo-062639	Monodelphis domestica	71.64	4.00e-110	390.00
IUUC-Mmu-063299	Mus musculus	83.12	2.00e-115	407.00
IUUC-Mac-065075	Musa acuminata	47.41	6.00e-53	200.00
IUUC-Mpu-066769	Mustela putorius furo	82.68	2.00e-115	407.00
IUUC-Mlu-066937	Myotis lucifugus	82.25	4.00e-115	406.00
IUUC-Nfi-068320	Neosartorya fischeri	38.72	8.00e-39	153.00
IUUC-Ncr-068673	Neurospora crassa	37.77	3.00e-42	164.00
IUUC-Nle-069175	Nomascus leucogenys	83.02	7.00e-106	376.00
IUUC-Opr-070652	Ochotona princeps	78.26	4.00e-52	197.00
IUUC-Ont-072170	Oreochromis niloticus	72.05	1.00e-89	322.00
IUUC-Oan-073247	Ornithorhynchus anatinus	82.46	5.00e-52	195.00
IUUC-Ocu-074422	Oryctolagus cuniculus	82.68	4.00e-115	406.00
IUUC-Oba-075098	Oryza barthii	42.22	2.00e-47	181.00
IUUC-Obr-076041	Oryza brachyantha	44.05	1.00e-49	189.00
IUUC-Ogl-076980	Oryza glaberrima	44.93	2.00e-49	188.00
IUUC-Ogu-078978	Oryza glumaepatula	38.89	2.00e-44	172.00
IUUC-Oin-079285	Oryza indica	41.78	1.00e-46	178.00
IUUC-Olo-080671	Oryza longistaminata	42.22	9.00e-47	179.00
IUUC-Ome-081428	Oryza meridionalis	41.33	2.00e-45	174.00
IUUC-Oni-082406	Oryza nivara	42.22	2.00e-47	181.00
IUUC-Opu-083305	Oryza punctata	41.78	3.00e-45	174.00
IUUC-Oru-084969	Oryza rufipogon	42.22	2.00e-47	181.00
IUUC-Osa-085830	Oryza sativa	44.93	2.00e-49	188.00
IUUC-Ola-086893	Oryzias latipes	68.56	7.00e-85	306.00
IUUC-Olu-087858	Ostreococcus lucimarinus	41.92	7.00e-48	183.00
IUUC-Oga-088055	Otolemur garnettii	83.12	2.00e-117	414.00
IUUC-Oar-090319	Ovis aries	81.82	4.00e-114	403.00
IUUC-Pan-092714	Papio anubis	82.68	1.00e-116	412.00
IUUC-Psi-094036	Pelodiscus sinensis	87.32	2.00e-104	370.00
IUUC-Pma-094412	Petromyzon marinus	62.58	1.00e-52	197.00
IUUC-Pno-094997	Phaeosphaeria nodorum	36.22	1.00e-31	129.00
IUUC-Ppa-095519	Physcomitrella patens	50.67	6.00e-62	229.00
IUUC-Pfo-096182	Poecilia formosa	70.13	7.00e-90	322.00
IUUC-Pab-098216	Pongo abelii	84.03	1.00e-70	257.00
IUUC-Pop-099282	Populus trichocarpa	46.46	7.00e-48	183.00
IUUC-Ppe-101332	Prunus persica	49.12	1.00e-55	208.00
IUUC-Pgr-103430	Puccinia graminis	44.35	1.00e-44	172.00
IUUC-Ptt-103955	Puccinia triticina	46.78	6.00e-46	176.00
IUUC-Pte-104414	Pyrenophora teres	39.74	2.00e-38	151.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	33.75	1.00e-30	125.00
IUUC-Rno-105096	Rattus norvegicus	81.82	7.00e-114	402.00
IUUC-Sce-106412	Saccharomyces cerevisiae	31.65	1.00e-22	99.80
IUUC-Sha-106677	Sarcophilus harrisii	79.57	2.00e-107	381.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	28.44	9.00e-22	96.30
IUUC-Ssl-108641	Sclerotinia sclerotiorum	36.91	2.00e-37	149.00
IUUC-Smo-109283	Selaginella moellendorffii	46.98	1.00e-49	189.00
IUUC-Sit-110163	Setaria italica	46.09	2.00e-50	191.00
IUUC-Sly-111613	Solanum lycopersicum	49.12	8.00e-58	216.00
IUUC-Stu-112526	Solanum tuberosum	49.12	7.00e-53	199.00
IUUC-Sbi-114545	Sorghum bicolor	45.18	2.00e-48	184.00
IUUC-Sre-114961	Sporisorium reilianum	39.22	1.00e-34	139.00
IUUC-Ssc-115255	Sus scrofa	82.08	1.00e-106	378.00
IUUC-Tgu-117003	Taeniopygia guttata	87.01	1.00e-112	398.00
IUUC-Tru-118330	Takifugu rubripes	64.13	9.00e-69	254.00
IUUC-Tsy-119488	Tarsius syrichta	78.95	6.00e-52	197.00
IUUC-Tni-120042	Tetraodon nigroviridis	65.41	1.00e-71	263.00
IUUC-Tca-120976	Theobroma cacao	47.35	3.00e-51	194.00
IUUC-Tre-122149	Trichoderma reesei	38.53	2.00e-40	159.00
IUUC-Tvi-122450	Trichoderma virens	38.10	4.00e-40	157.00
IUUC-Tae-122693	Triticum aestivum	44.10	1.00e-48	186.00
IUUC-Tur-126250	Triticum urartu	42.13	6.00e-47	180.00
IUUC-Tme-126961	Tuber melanosporum	36.44	7.00e-33	133.00
IUUC-Uma-129382	Ustilago maydis	37.77	1.00e-37	149.00
IUUC-Vda-129678	Verticillium dahliae	32.35	5.00e-30	124.00
IUUC-Vpa-130783	Vicugna pacos	77.39	1.00e-51	196.00
IUUC-Vvi-131661	Vitis vinifera	45.13	1.00e-51	196.00
IUUC-Xtr-132428	Xenopus tropicalis	71.86	2.00e-102	364.00
IUUC-Xma-134245	Xiphophorus maculatus	68.56	1.00e-88	318.00
IUUC-Yli-134570	Yarrowia lipolytica	36.25	9.00e-34	136.00
IUUC-Zma-134740	Zea mays	44.30	3.00e-49	187.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence