iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055888

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

JSUE03018629

Gene Name

UCHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000003560.3	ENSMMUT00000005031.3	ENSMMUP00000004740.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	2.30e-67	228.9	3	228

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 5    vkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakq 93
           +++wl+Le++P++   +++++g++ ++q+ ++y++dpe l+++++pv+++lllF+i+ek+e +r+++   ++++++++ ++++++f+kq
   Q: 3    GQRWLPLEANPEV--GFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEE--EEKIKSQGQAVTSSVYFMKQ 87
           589*********9..699**********************************************766..5589**************** PP
   S: 94   vigNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfv 181
           +i+N+C+t++l+++++n++dk+ ++ G+tl++++e++ ++spe++a+ l+n ++++++h++ a+++++++p+ +       +k  +hf+
   Q: 88   TISNACGTIGLIHAIANNKDKMhFESGSTLKKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTEAPNID-------EKVDLHFI 169
           ***********************************************************************877.......7899**** PP
   S: 182  syvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           ++v+++g+lyeldg+kpfP+++g++++++ l+d+++v+++f+er    + de+rfn++a++a+
   Q: 170  ALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMER----DPDELRFNAIALSAA 228
           ********************************************....***********9875 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MEGQRWLPLE ANPEVGFLKQ LGLHPNWQFV DVYGMDPELL SMVPRPVCAV LLLFPITEKY 60
EVFRTEEEEK IKSQGQAVTS SVYFMKQTIS NACGTIGLIH AIANNKDKMH FESGSTLKKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGGAAGAGT CCAAGCGTGA GGGGACAGGA CTGTGAATTC AGATACTGTT TTTCTCCCGA 60
AATAGGTATT TGGCTTCTAT TTTTTTCCTC CTCGACAGCA TCTTAATTTG AAATATGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000360	Aegilops tauschii	43.22	3.00e-50	191.00
IUUC-Aml-001344	Ailuropoda melanoleuca	97.83	1.00e-132	464.00
IUUC-Atr-002931	Amborella trichopoda	48.11	3.00e-48	184.00
IUUC-Apl-003949	Anas platyrhynchos	86.32	1.00e-102	365.00
IUUC-Aca-004924	Anolis carolinensis	80.95	3.00e-112	397.00
IUUC-Aly-005721	Arabidopsis lyrata	49.34	5.00e-57	214.00
IUUC-Ath-006827	Arabidopsis thaliana	50.00	2.00e-57	215.00
IUUC-Ago-007950	Ashbya gossypii	35.14	2.00e-26	112.00
IUUC-Acl-008305	Aspergillus clavatus	39.82	7.00e-40	157.00
IUUC-Afl-008611	Aspergillus flavus	40.25	6.00e-42	164.00
IUUC-Afu-008945	Aspergillus fumigatus	40.34	1.00e-41	162.00
IUUC-Ani-009339	Aspergillus nidulans	40.51	3.00e-42	164.00
IUUC-Ang-009691	Aspergillus niger	38.72	3.00e-41	161.00
IUUC-Aor-009961	Aspergillus oryzae	40.25	6.00e-42	164.00
IUUC-Ate-010316	Aspergillus terreus	40.85	1.00e-42	166.00
IUUC-Ame-011157	Astyanax mexicanus	71.74	1.00e-97	349.00
IUUC-Bgr-012125	Blumeria graminis	36.17	1.00e-37	149.00
IUUC-Bta-012673	Bos taurus	97.83	1.00e-132	464.00
IUUC-Bci-013734	Botrytis cinerea	38.03	1.00e-41	162.00
IUUC-Bdi-014330	Brachypodium distachyon	45.81	1.00e-53	202.00
IUUC-Bol-015214	Brassica oleracea	51.54	3.00e-60	224.00
IUUC-Bra-017491	Brassica rapa	51.98	9.00e-60	223.00
IUUC-Cfa-020371	Canis familiaris	96.32	5.00e-106	376.00
IUUC-Cpo-022036	Cavia porcellus	95.22	2.00e-127	447.00
IUUC-Cre-022599	Chlamydomonas reinhardtii	44.19	4.00e-36	144.00
IUUC-Csa-023854	Chlorocebus sabaeus	98.70	4.00e-133	467.00
IUUC-Cin-025545	Ciona intestinalis	49.33	1.00e-63	236.00
IUUC-Cgl-026659	Colletotrichum gloeosporioides	34.63	5.00e-30	124.00
IUUC-Cne-026914	Cryptococcus neoformans	35.50	1.00e-30	125.00
IUUC-Cme-027216	Cyanidioschyzon merolae	36.49	1.00e-24	106.00
IUUC-Dre-028356	Danio rerio	73.48	7.00e-100	356.00
IUUC-Dse-031461	Dothistroma septosporum	40.51	1.00e-37	149.00
IUUC-Dme-032146	Drosophila melanogaster	51.11	4.00e-61	227.00
IUUC-Eca-033220	Equus caballus	97.39	2.00e-131	461.00
IUUC-Fca-036421	Felis catus	97.83	1.00e-132	464.00
IUUC-Fal-036773	Ficedula albicollis	86.32	2.00e-102	364.00
IUUC-Fox-037830	Fusarium oxysporum	36.80	2.00e-39	155.00
IUUC-Fso-038259	Fusarium solani	36.68	9.00e-38	152.00
IUUC-Gmo-039468	Gadus morhua	68.42	2.00e-83	301.00
IUUC-Ggr-039832	Gaeumannomyces graminis	37.12	1.00e-35	142.00
IUUC-Gga-041205	Gallus gallus	84.35	2.00e-108	384.00
IUUC-Gac-041629	Gasterosteus aculeatus	67.98	1.00e-85	309.00
IUUC-Gma-043057	Glycine max	48.90	6.00e-50	190.00
IUUC-Ggo-044533	Gorilla gorilla	97.40	2.00e-132	464.00
IUUC-Hsa-046754	Homo sapiens	97.83	1.00e-132	464.00
IUUC-Hvu-047176	Hordeum vulgare	39.74	5.00e-40	157.00
IUUC-Itr-047992	Ictidomys tridecemlineatus	96.84	4.00e-88	316.00
IUUC-Kpa-049123	Komagataella pastoris	35.68	2.00e-30	125.00
IUUC-Lch-049685	Latimeria chalumnae	77.19	2.00e-106	377.00
IUUC-Lpe-051377	Leersia perrieri	44.33	3.00e-43	167.00
IUUC-Loc-051988	Lepisosteus oculatus	75.22	3.00e-102	364.00
IUUC-Lma-053316	Leptosphaeria maculans	40.26	5.00e-41	160.00
IUUC-Laf-053985	Loxodonta africana	96.10	7.00e-131	459.00
IUUC-Mor-057271	Magnaporthe oryzae	37.12	2.00e-39	155.00
IUUC-Mpo-057343	Magnaporthe poae	32.34	4.00e-21	94.00
IUUC-Mtr-057713	Medicago truncatula	47.58	2.00e-50	191.00
IUUC-Mla-058942	Melampsora laricipopulina	44.93	6.00e-45	173.00
IUUC-Mga-059702	Meleagris gallopavo	85.85	4.00e-102	363.00
IUUC-Mvi-060249	Microbotryum violaceum	43.86	3.00e-40	158.00
IUUC-Mmr-061284	Microcebus murinus	97.47	1.00e-87	316.00
IUUC-Mdo-062639	Monodelphis domestica	77.99	9.00e-118	416.00
IUUC-Mmu-063299	Mus musculus	96.09	1.00e-130	458.00
IUUC-Mac-065075	Musa acuminata	44.54	2.00e-50	192.00
IUUC-Mpu-066769	Mustela putorius furo	97.83	1.00e-132	464.00
IUUC-Mlu-066937	Myotis lucifugus	95.65	1.00e-128	452.00
IUUC-Nfi-068320	Neosartorya fischeri	40.76	2.00e-42	166.00
IUUC-Ncr-068673	Neurospora crassa	38.96	9.00e-44	170.00
IUUC-Nle-069175	Nomascus leucogenys	99.06	5.00e-124	436.00
IUUC-Opr-070652	Ochotona princeps	99.13	4.00e-63	234.00
IUUC-Ont-072170	Oreochromis niloticus	70.18	5.00e-87	313.00
IUUC-Oan-073247	Ornithorhynchus anatinus	90.27	8.00e-55	204.00
IUUC-Ocu-074422	Oryctolagus cuniculus	96.96	4.00e-132	463.00
IUUC-Oba-075098	Oryza barthii	41.15	3.00e-47	181.00
IUUC-Obr-076041	Oryza brachyantha	43.86	7.00e-51	193.00
IUUC-Ogl-076980	Oryza glaberrima	44.30	1.00e-50	192.00
IUUC-Ogu-078978	Oryza glumaepatula	37.94	1.00e-44	172.00
IUUC-Oin-079285	Oryza indica	40.71	2.00e-46	178.00
IUUC-Olo-080671	Oryza longistaminata	41.15	1.00e-46	179.00
IUUC-Ome-081428	Oryza meridionalis	40.27	3.00e-45	174.00
IUUC-Oni-082406	Oryza nivara	41.15	3.00e-47	181.00
IUUC-Opu-083305	Oryza punctata	41.15	1.00e-45	176.00
IUUC-Oru-084969	Oryza rufipogon	41.15	3.00e-47	181.00
IUUC-Osa-085830	Oryza sativa	44.30	1.00e-50	192.00
IUUC-Ola-086893	Oryzias latipes	67.98	2.00e-83	301.00
IUUC-Olu-087858	Ostreococcus lucimarinus	44.49	2.00e-50	192.00
IUUC-Oga-088055	Otolemur garnettii	97.40	2.00e-132	464.00
IUUC-Oar-090319	Ovis aries	97.39	5.00e-132	462.00
IUUC-Pan-092714	Papio anubis	98.27	8.00e-134	468.00
IUUC-Psi-094036	Pelodiscus sinensis	86.32	8.00e-103	366.00
IUUC-Pma-094412	Petromyzon marinus	62.99	3.00e-51	193.00
IUUC-Pno-094997	Phaeosphaeria nodorum	36.22	2.00e-33	136.00
IUUC-Ppa-095519	Physcomitrella patens	50.22	2.00e-61	228.00
IUUC-Pfo-096182	Poecilia formosa	67.39	3.00e-86	311.00
IUUC-Pab-098216	Pongo abelii	99.31	1.00e-82	298.00
IUUC-Pop-099282	Populus trichocarpa	47.79	7.00e-50	190.00
IUUC-Ppe-101332	Prunus persica	47.35	1.00e-52	199.00
IUUC-Pgr-103430	Puccinia graminis	47.48	1.00e-48	186.00
IUUC-Ptt-103955	Puccinia triticina	48.28	3.00e-49	188.00
IUUC-Pte-104414	Pyrenophora teres	39.32	3.00e-39	155.00
IUUC-Pyt-104753	Pyrenophora triticirepentis	33.19	6.00e-32	130.00
IUUC-Rno-105096	Rattus norvegicus	95.22	2.00e-129	454.00
IUUC-Sce-106412	Saccharomyces cerevisiae	36.08	5.00e-27	114.00
IUUC-Sha-106677	Sarcophilus harrisii	93.40	1.00e-117	415.00
IUUC-Sja-107753	Schizosaccharomyces japonicus	30.95	2.00e-25	108.00
IUUC-Spo-108322	Schizosaccharomyces pombe	30.57	4.00e-24	104.00
IUUC-Ssl-108641	Sclerotinia sclerotiorum	36.64	2.00e-37	149.00
IUUC-Smo-109283	Selaginella moellendorffii	48.07	6.00e-51	193.00
IUUC-Sit-110163	Setaria italica	46.55	3.00e-52	198.00
IUUC-Sly-111613	Solanum lycopersicum	48.46	1.00e-58	219.00
IUUC-Stu-112526	Solanum tuberosum	49.56	4.00e-54	204.00
IUUC-Sbi-114545	Sorghum bicolor	46.29	7.00e-51	193.00
IUUC-Sre-114961	Sporisorium reilianum	41.63	1.00e-38	152.00
IUUC-Ssc-115255	Sus scrofa	97.64	1.00e-122	431.00
IUUC-Tgu-117003	Taeniopygia guttata	85.15	6.00e-109	386.00
IUUC-Tru-118330	Takifugu rubripes	62.30	3.00e-66	246.00
IUUC-Tsy-119488	Tarsius syrichta	97.37	3.00e-62	231.00
IUUC-Tni-120042	Tetraodon nigroviridis	63.04	1.00e-67	250.00
IUUC-Tca-120976	Theobroma cacao	47.35	5.00e-52	197.00
IUUC-Tre-122149	Trichoderma reesei	38.70	2.00e-42	165.00
IUUC-Tvi-122450	Trichoderma virens	38.70	5.00e-42	164.00
IUUC-Tae-122693	Triticum aestivum	43.91	7.00e-50	191.00
IUUC-Tur-126250	Triticum urartu	43.22	8.00e-50	189.00
IUUC-Tme-126961	Tuber melanosporum	36.60	1.00e-34	139.00
IUUC-Uma-129382	Ustilago maydis	41.38	6.00e-42	164.00
IUUC-Vda-129678	Verticillium dahliae	31.22	6.00e-29	120.00
IUUC-Vpa-130783	Vicugna pacos	98.26	1.00e-62	233.00
IUUC-Vvi-131661	Vitis vinifera	47.16	1.00e-53	202.00
IUUC-Xtr-132428	Xenopus tropicalis	73.04	2.00e-103	368.00
IUUC-Xma-134245	Xiphophorus maculatus	66.67	3.00e-86	311.00
IUUC-Yli-134570	Yarrowia lipolytica	36.32	6.00e-36	144.00
IUUC-Zma-134740	Zea mays	45.41	2.00e-52	199.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence