iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033791

Ensembl Protein ID

ENSECAP00000022840.1

UniProt Accession

F6R1H4; F6R1H4_HORSE

Protein Name

Uncharacterized protein

Gene Name

ARHGAP26

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000012336.2	ENSECAT00000013220.1	ENSECAP00000010475.1
ENSECAG00000012336.2	ENSECAT00000013257.1	ENSECAP00000010509.1
ENSECAG00000012336.2	ENSECAT00000028861.1	ENSECAP00000022840.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-12	47.4	760	812

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           k ++ly  +a++d eL++++G v + + + +q+ gWl+g  +l+gk Gl+Pen+ve
   Q: 760  KAKALYACKAEHDSELSFTAGTVFDNV-HPSQEPGWLEG--TLNGKTGLIPENYVE 812
           679************************.***********..8*************8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

GAPALEFSDC CLDSPHFRET LKSHEAELDK TNKFIKELIK DGKSLISALK NLSSAKRKFA 60
DSLNEFKFQC IGDAETDDEM CIARSLQEFA TVLRNLEDER IRMIENASEV LITPLEKFRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCTCCCG CTCTCGAATT CAGCGACTGC TGCCTCGACA GCCCGCACTT CCGAGAGACG 60
CTCAAGTCGC ACGAAGCGGA GCTGGACAAG ACCAACAAAT TCATCAAGGA GCTCATCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR030061--RHG26
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005096--F:GTPase activator activity
GO:0005543--F:phospholipid binding
GO:0030036--P:actin cytoskeleton organization
GO:0051056--P:regulation of small GTPase mediated signal transduction
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001613	Ailuropoda melanoleuca	98.53	0.00e+00	1390.00
IUUC-Apl-003321	Anas platyrhynchos	86.10	0.00e+00	1145.00
IUUC-Aca-004570	Anolis carolinensis	89.55	0.00e+00	1162.00
IUUC-Ame-011422	Astyanax mexicanus	78.48	0.00e+00	849.00
IUUC-Bta-013262	Bos taurus	98.52	0.00e+00	1113.00
IUUC-Cel-018542	Caenorhabditis elegans	43.19	5.00e-131	462.00
IUUC-Cja-019208	Callithrix jacchus	99.35	0.00e+00	1199.00
IUUC-Cfa-020928	Canis familiaris	98.48	0.00e+00	1213.00
IUUC-Cpo-021338	Cavia porcellus	96.93	0.00e+00	1423.00
IUUC-Csa-023570	Chlorocebus sabaeus	99.02	0.00e+00	1196.00
IUUC-Cin-025725	Ciona intestinalis	43.79	3.00e-131	462.00
IUUC-Dno-029143	Dasypus novemcinctus	98.16	0.00e+00	1424.00
IUUC-Dor-030697	Dipodomys ordii	96.68	0.00e+00	1407.00
IUUC-Dme-032147	Drosophila melanogaster	44.26	2.00e-138	486.00
IUUC-Ete-032645	Echinops telfairi	88.89	0.00e+00	1046.00
IUUC-Eeu-035202	Erinaceus europaeus	84.92	0.00e+00	631.00
IUUC-Fca-036131	Felis catus	98.50	0.00e+00	1402.00
IUUC-Fal-037129	Ficedula albicollis	91.50	0.00e+00	1130.00
IUUC-Gga-041023	Gallus gallus	91.96	0.00e+00	1171.00
IUUC-Ggo-044863	Gorilla gorilla	97.06	0.00e+00	1412.00
IUUC-Hsa-046471	Homo sapiens	96.93	0.00e+00	1407.00
IUUC-Itr-049060	Ictidomys tridecemlineatus	96.44	0.00e+00	1440.00
IUUC-Lch-050300	Latimeria chalumnae	76.19	0.00e+00	1037.00
IUUC-Loc-052782	Lepisosteus oculatus	80.37	0.00e+00	1048.00
IUUC-Laf-053585	Loxodonta africana	97.17	0.00e+00	1390.00
IUUC-Mcc-055458	Macaca mulatta	99.19	0.00e+00	1200.00
IUUC-Meu-056107	Macropus eugenii	77.52	0.00e+00	1080.00
IUUC-Mga-059914	Meleagris gallopavo	89.41	0.00e+00	1043.00
IUUC-Mmr-060728	Microcebus murinus	96.72	0.00e+00	1310.00
IUUC-Mdo-062387	Monodelphis domestica	90.18	0.00e+00	1336.00
IUUC-Mmu-063756	Mus musculus	97.89	0.00e+00	1210.00
IUUC-Nle-069043	Nomascus leucogenys	93.75	0.00e+00	881.00
IUUC-Opr-071168	Ochotona princeps	83.54	0.00e+00	1194.00
IUUC-Ont-072338	Oreochromis niloticus	77.31	0.00e+00	894.00
IUUC-Oan-073441	Ornithorhynchus anatinus	92.64	0.00e+00	979.00
IUUC-Ocu-073915	Oryctolagus cuniculus	94.72	0.00e+00	1387.00
IUUC-Ola-086319	Oryzias latipes	76.24	0.00e+00	929.00
IUUC-Oar-089349	Ovis aries	98.17	0.00e+00	1208.00
IUUC-Ptr-091027	Pan troglodytes	97.05	0.00e+00	1410.00
IUUC-Pan-092791	Papio anubis	99.19	0.00e+00	1198.00
IUUC-Psi-093144	Pelodiscus sinensis	91.96	0.00e+00	1214.00
IUUC-Pab-097783	Pongo abelii	96.93	0.00e+00	1413.00
IUUC-Pva-102980	Pteropus vampyrus	97.54	0.00e+00	1466.00
IUUC-Rno-105142	Rattus norvegicus	97.26	0.00e+00	1234.00
IUUC-Sha-107213	Sarcophilus harrisii	93.29	0.00e+00	1118.00
IUUC-Tgu-117313	Taeniopygia guttata	83.00	0.00e+00	779.00
IUUC-Tru-117767	Takifugu rubripes	76.63	0.00e+00	969.00
IUUC-Tsy-119150	Tarsius syrichta	94.35	0.00e+00	1376.00
IUUC-Tni-119893	Tetraodon nigroviridis	76.32	0.00e+00	687.00
IUUC-Ttr-129028	Tursiops truncatus	88.09	0.00e+00	1128.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence