iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000017296.4	ENSCAFT00000049082.2	ENSCAFP00000036514.1
ENSCAFG00000017296.4	ENSCAFT00000027404.3	ENSCAFP00000025484.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-09	38.8	633	670

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC++d+k   +++pC H+fha Cl+kw       + + +CPlC
   Q: 633  CAICYQDMKS-AVITPCSHFFHAGCLKKW------LYVQETCPLC 670
           ********99.888***************......********** PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MQRDVNNSRS RFGHDGRKAK SQVSCLPSFL DKTNAIAMPF LVLCLERADF WGQFLTEPAG 60
VSRLLAFPAP SLRNMKQKEN PGNSLPCLLR SAPRKNMAAK EKLEAVLNVA LRVPSIMLLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAACGGT AAACTGAGGA CCCGCAGAAA AGGGAAGGGG TGAGCCTAAG TCACTCCGAG 60
AACCAAAGAA GCAGATCTCA GTACGAGAGC TGCCATCGAG GTCACTAAAG TAGGGCATCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002354	Ailuropoda melanoleuca	98.21	0.00e+00	1254.00
IUUC-Apl-003823	Anas platyrhynchos	89.57	0.00e+00	1120.00
IUUC-Aca-004944	Anolis carolinensis	93.20	0.00e+00	1107.00
IUUC-Ame-011578	Astyanax mexicanus	89.12	0.00e+00	1009.00
IUUC-Bta-012560	Bos taurus	89.83	0.00e+00	1180.00
IUUC-Cel-018539	Caenorhabditis elegans	28.33	4.00e-63	236.00
IUUC-Cja-018929	Callithrix jacchus	94.46	0.00e+00	1202.00
IUUC-Cpo-022452	Cavia porcellus	94.55	0.00e+00	1176.00
IUUC-Csa-024116	Chlorocebus sabaeus	96.52	0.00e+00	1216.00
IUUC-Csv-025845	Ciona savignyi	41.14	8.00e-33	132.00
IUUC-Dre-027493	Danio rerio	82.49	0.00e+00	1023.00
IUUC-Dno-029615	Dasypus novemcinctus	95.07	0.00e+00	1212.00
IUUC-Ete-032551	Echinops telfairi	70.74	0.00e+00	853.00
IUUC-Eca-033349	Equus caballus	97.75	0.00e+00	1127.00
IUUC-Eeu-035349	Erinaceus europaeus	97.34	0.00e+00	717.00
IUUC-Fca-035696	Felis catus	97.46	0.00e+00	1250.00
IUUC-Fal-037495	Ficedula albicollis	88.52	0.00e+00	1094.00
IUUC-Gmo-039374	Gadus morhua	84.52	0.00e+00	1001.00
IUUC-Gga-040146	Gallus gallus	91.50	0.00e+00	1112.00
IUUC-Gac-041731	Gasterosteus aculeatus	84.16	0.00e+00	1024.00
IUUC-Ggo-045158	Gorilla gorilla	96.79	0.00e+00	1209.00
IUUC-Hsa-045787	Homo sapiens	96.68	0.00e+00	1221.00
IUUC-Itr-048928	Ictidomys tridecemlineatus	95.86	0.00e+00	1102.00
IUUC-Lch-050499	Latimeria chalumnae	91.43	0.00e+00	1060.00
IUUC-Loc-052482	Lepisosteus oculatus	91.04	0.00e+00	1045.00
IUUC-Laf-053362	Loxodonta africana	96.23	0.00e+00	1209.00
IUUC-Mcc-055779	Macaca mulatta	96.49	0.00e+00	1202.00
IUUC-Meu-056130	Macropus eugenii	71.98	1.00e-148	520.00
IUUC-Mga-059742	Meleagris gallopavo	91.36	0.00e+00	1109.00
IUUC-Mmr-060812	Microcebus murinus	95.56	0.00e+00	1231.00
IUUC-Mdo-063045	Monodelphis domestica	91.08	0.00e+00	1131.00
IUUC-Mmu-064377	Mus musculus	94.40	0.00e+00	1193.00
IUUC-Mpu-066637	Mustela putorius furo	98.23	0.00e+00	1271.00
IUUC-Mlu-066985	Myotis lucifugus	95.30	0.00e+00	1196.00
IUUC-Nle-069833	Nomascus leucogenys	96.49	0.00e+00	1204.00
IUUC-Opr-070210	Ochotona princeps	85.61	3.00e-138	485.00
IUUC-Ont-072116	Oreochromis niloticus	83.54	0.00e+00	1038.00
IUUC-Oan-073730	Ornithorhynchus anatinus	90.80	0.00e+00	1138.00
IUUC-Ocu-074958	Oryctolagus cuniculus	95.16	0.00e+00	1200.00
IUUC-Ola-087368	Oryzias latipes	89.29	0.00e+00	1023.00
IUUC-Oga-088301	Otolemur garnettii	96.63	0.00e+00	1206.00
IUUC-Oar-089745	Ovis aries	94.77	0.00e+00	1198.00
IUUC-Ptr-091397	Pan troglodytes	96.53	0.00e+00	1220.00
IUUC-Pan-092817	Papio anubis	96.67	0.00e+00	1218.00
IUUC-Psi-093820	Pelodiscus sinensis	87.09	0.00e+00	1072.00
IUUC-Pma-094457	Petromyzon marinus	66.87	3.00e-171	594.00
IUUC-Pfo-097173	Poecilia formosa	83.41	0.00e+00	1029.00
IUUC-Pab-097630	Pongo abelii	96.52	0.00e+00	1212.00
IUUC-Pca-100472	Procavia capensis	91.43	0.00e+00	1173.00
IUUC-Pva-102485	Pteropus vampyrus	94.74	0.00e+00	1132.00
IUUC-Rno-106029	Rattus norvegicus	95.01	0.00e+00	1159.00
IUUC-Sha-106580	Sarcophilus harrisii	91.34	0.00e+00	1154.00
IUUC-Ssc-116438	Sus scrofa	93.37	0.00e+00	1087.00
IUUC-Tgu-116638	Taeniopygia guttata	89.59	0.00e+00	1091.00
IUUC-Tru-117779	Takifugu rubripes	84.47	0.00e+00	1031.00
IUUC-Tsy-119541	Tarsius syrichta	93.69	0.00e+00	1142.00
IUUC-Tni-119862	Tetraodon nigroviridis	85.48	0.00e+00	1030.00
IUUC-Tbe-127328	Tupaia belangeri	90.02	0.00e+00	1058.00
IUUC-Ttr-129066	Tursiops truncatus	95.60	3.00e-180	625.00
IUUC-Xtr-132826	Xenopus tropicalis	87.65	0.00e+00	1087.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence